Tomo, though the characters tend to treat her appropriately. Yomi occasionally hits her, but probably not as often as she deserves. Although there are quite a few examples that show Tomo does care.Getting scratched by Maya is taken as an opportunity for Yomi and Kagura to point out several times over that she should learn a lesson about how she treats others. It goes over her head.
Also Yukari. You can just tell she's got no other friends apart from Nyamo. But then, strangely, neither does Nyamo. This may be justified, though, because they work at a Three ...ish Teacher School, and the third teacher, Kimura, is a Dirty Old Man. And then there's that one no one remembers who made Chiyo freak out.
Kamineko surpasses them all. That cat is evil. Perhaps its worst act is when, near the end of the series, it responds to Sakaki's apology for offending it by trying to pet it many times by offering to let her pet it, and then biting her hand again.
Ishizawa is incredibly arrogant, thinking he's better than Mashiro when he can't draw anything other than cutesy girls in the same pose. After he insults Mashiro's artwork despite not having tried anything like Mashiro did, Takagi becomes enraged and punches him. Ishizawa later ends up being the one to publicize the news about Mashiro and Azuki's relationship, thus causing her great difficulty in getting the lead role in Mashiro's anime.
Nakai becomes one over time, such as by making becoming his girlfriend a condition of collaborating with a fellow mangaka. He later ends up as Nanamine's assistant and tends to treat the others poorly unless they're women and attractive.
Nanamine plans on rising to the top of Jump with online collaborators, and later, using out of work mangaka to test his new method, but views everyone as utterly expendable, blackmails his editor, Kosugi, into accepting his proposal by threatening to go elsewhere, and is fairly arrogant and short-tempered. Sasaki gives him a This Is Unforgivable speech after learning about him casting his mangaka aside, and Kosugi gives him a "The Reason You Suck" Speech, saying that because he has no empathy for others, he can't write believable characters.
Black Lagoon has a cast that's almost all villains, but even among them, Chaka stands out for sheer Jerkassery. From the moment we see him he gets a call on his cell when he's supposed to be in a meeting, and tells his girlfriend that for calling him when he said not to call, he's going to knock some of her teeth out to later when he beats Rock without any provocation on Rock's part, to try to get Revy either interested in him or into a gunfight — the concepts are mixed in his mind and his final exploit where he kidnaps Yukio, strips her half-naked with the help of his Mooks and plans to rape her and sell her into sexual slavery, he goes on in the same old way. He gets his comeuppance big-time when Ginji Matsuzaki, the Badass guardian of Yukio, slices up his gun, chops off his hands, and sends him into a swimming pool to drown.
Sosuke Aizen, Nnoitra, Szayel, Yammy, Loly and the Vandereich, especially the leader.
Candy's bitchy stepsister Eliza from Candy Candy, who gets a kick out of using her money and status (among other things) to humiliate Candy and those of lesser status than her. For the lulz. The only thing that prevents her from being a monster is that she doesn't send Candy into deadly slave labor.
The whole soccer club in CLANNAD are made of douchebags, it is no wonder why Sunohara left the club since day one. This gets even worse in the Sunohara path (and in After Story anime adaptation), when Youhei's sister Mei asks to let her brother rejoin to get his spirit back, they instantly dismiss him roughly. Then when Tomoya helps out in requesting, they tell him, Mei and Nagisa to be ball-catcher, and purposely throw the ball out just so they can see the three struggle. And when Mei begs about it again, they start bullying her on purpose.
Tsuchimikaido A Certain Magical Index is a fair bit of this, especially in the light novels where he picks on Kanzaki and her love for Touma and the way he gets Touma's help in a couple international incidents.
Kanda Yu, from D.Gray-Man, is the sort of guy who threatens to kill his allies when they try to help him out with a fight. Or steal his hair tie. But since he's freaking gorgeous and incrediblytraumatized, we tend to cut him some slack. Kanda gets a lot better in later arcs (threatening to kill his friends starts sounding pretty unconvincing), but his real Jerkass moment was when he callously considered all non-exorcists cannon fodder in the first volume of the manga and bullies a weaker man (granted, the weaker man looked stronger, but it's obvious that Kanda's more powerful).
Ruki Makino (Rika Nonaka) in Digimon Tamers was absolutely unsufferable at first, mocking poor Takato and Jenrya for being friendly to their Digimon, putting them down every chance she got, and ordering her partner Renamon to kill Guilmon and absorb his data, only so that Renamon could get stronger. Later Character Development mellows her out, turning her into a Defrosting Ice Queen.
Vegeta from Dragon Ball Z. In the early stages of the anime, the arrogant prince of the Saiyans is a complete genocidal asshole with nary a nice bone in his body, constantly insulting his teammates even after doing the Heel-Face Turn, and being perpetually jealous of his Future Badass son Trunks. He does mellow out once the sense of family with Bulma and Trunks sets in for him. Which takes some time.
Izaya Orihara from Durarara!!. The first time you properly see him in the anime, he spends most of the episode orchestrating the kidnapping and rescue of a girl he spoke to online, only to hold her over the side of a building, toy with her desire (or lack thereof) to actually commit suicide, and then wander off to watch from a distance as the girl decides to jump anyway. (Luckily for her, someone else was a little more worried about her safety and saves her.) Anyone who meets him in the series is wary of him, has a number of tales to tell about how manipulative and dangerous he is to be around, or just skip the talking completely and throw vending machines in his face.
Bando from Elfen Lied. In his introduction, he casually backhands a woman for the hell of it, laughs, then calls her an idiot for "sneaking up on him". And all she was doing was bringing him some tea. He later punches a doctor in the face with his new prosthetic hand moments after the doctor installs it in order to "test it out".
In Eyeshield21 it sure seems like Hiruma is going to be the (only) resident jerkass, until Jerk Jock Agon comes along. The only area where Agon doesn't fit this trope's definition of jerkass perfectly is that he knows his behavior is inappropriate, excessive and/or cruel, and he's fine with that.
Luxus from Fairy Tail. One of the most powerful mages in the guild (the most powerful, according to him, but he's pretty full of himself so that might not be very accurate), he has absolutely no redeeming features and seems to exist solely to anger other people, and try to get into the pants of the guild's female members. His accomplishments thus far include goading the protagonists into putting themselves into life-threatening danger, refusing to help in the conflict with rival guild Phantom Lord, even after the Guild Master, Makarov, was badly injured in the fight, and afterwards mocking the people who got hurt in the conflict, calling them weaklings. When he succeeds Makarov as the guild's master, he fully intends to rid the guild of anyone he deems too weak. He's quite certain he'll be named the next guild master, as not only is he the only qualified mage in the guild at the moment, he's also Makarov's flesh-and-blood grandson. This is, in fact, precisely the reason why Makarov hasn't retired yet: because he knows that if he does so, Fairy Tail will be left in his Jerk Ass grandson's hands. Tired of waiting for his inheritance, he as pit the entirety of Fairy Tail against itself in an Involuntary Battle to the Death situation. This is accomplished by turning the guild's female members to stone, threatening that they'll turn to dust if not healed soon, then setting up various traps that won't fade unless the male members fight one another. When this fails, by virtue of the hostages being freed, Luxus ups the ante and takes the entire town hostage. All to force Makarov to step down as master and place himself there instead. Although, it turns out he has a Freudian Excuse. Afterwards, Laxus improves inpersonality.
In the Time Skip, Sabertooth is a guild full of such people with their former Guild Master Jiemma and Minerva taking the trope and running with it to escalating levels.
Envy is not only one of the more evil homunculi, but he also enjoys taunting and insulting his enemies, prisoners, allies and fellow homunculi.
Basque Grand is also a huge one in the first anime, to the point that it's actually surprising when in the manga, he turns out to have been a far more reasonable man. Case in point, during this Ishvalan War, he stands up for all his fellow comrades and shoots his own jerkass superior dead when he tries to prevent the Ishbalan religious leader from negotiating with the Fuhrer to end the conflict - and everyone around implicitly agrees with this action.
Futana from Futaba-kun Change!. She even attempts to sexually molest her own brother and at one point vomits into his mouth simply because he is closer than the toilet is.
Kei Kurono. He gets better though. Then he dies. Then he, un-dies.
And Nishi when, after gaining 100 points, instead of choosing to revive Inaba, he chooses a new weapon, leaving him dead.
Kirie Kojima in season 1 of Girls Bravo as shown by her frequently (and unfairly) beating up her 'best friend' Yukinari, despite knowing he's scared of girls because of her actions and developed a rash to girls because of it. Really, acts of kindness on her part don't really hold much water when she just immediately follows these acts of kindness with frequent beatings and verbal abuse. She's only a Jerkass in season 1, as she becomes much nicer in season 2. However, even in the second season her actions are questionable, like when she emotionally manipulated Yukinari into cross-dressing for an event and allowed him to get molested by Fukuyama since it meant Fukuyama would pay her.
Erika Itsumi, Maho's vice captain and Miho's successor in that position. She's introduced mocking Miho and the rest of Oarai as a no-name school that shouldn't even enter the tournament, complains about Maho letting Mako and Saori borrow their team's helicopter to quickly get to Mako's grandmother in the hospital, and shoots a nasty glare at one of her teammates when she goes over to thank Miho for saving them, an act that resulted in Black Forest losing the tournament for the first time in a decade. She gets slightly better after her defeat by Miho in the final, smiling and swearing that they'll beat them next time.
Miho's mother, Shiho Nishizumi has a cold and abrasive personality, and after one meeting with her in Little Army, Miho's friends consider her "a scary mother", and immediately notice that Maho acts differently when Shiho's around, unable to oppose her. Shiho considers Miho a disgrace to the family and is planning to disown her.
Anchovy, commander of Anzio Academy's tankery crew, goes up to Miho before the match and calls her way of tankery weak. After her defeat, she's so far the only commander who is not a Graceful Loser, and accuses Miho of causing her own team's defeat in the last tournament by way of the aforementioned rescue of a teammate.
Anzu Kadotani, the Student Council President of Ōarai Girls' Academy, comes off as this when she's introduced by pressuring Miho to take Tankery ( Though the reason for going to extremes was because the school was in danger of being shut down if they didn't win the Tankery tournament) and acting manipulative and high hosed.
Emi Nakasuka of the Little Army prequel manga starts out as this, being someone who speaks whatever is on her mind no matter how much it hurts others, causing friction within her group of friends, and is bitter toward Maho because she shot her older sister's team's flag tank when it went to rescue one of Maho's teammates. Over time, Emi becomes a Jerk with a Heart of Gold who is able to force Miho to confront her own problems.
Amuro Ray, Kamille Bidan, Judau Ashta, Setsuna F. Seiei, etc... you name it!
Nena Trinity from 00 especially deserves mentioning, being The Fake Cutie who enjoys killing people simply out of boredom.
Mamoru Takamura from Hajime No Ippo has always been portrayed as being serious and knowledgeable when it came to boxing, but a big jerk in anything not related to it. This is the guy who actually pranks the new boxers by surprising them in the showers and grabbing their cocks, after all. He hits kids who want an autograph from him.
In Happy Yarou Wedding, Kazuki is none too nice to his brother-in-law Yuuhi, especially over his sexuality. On the flip side he's a good uncle to Shouta which is why Yuuhi tolerates him at all.
Sakuya is a textbook example. Her cousin and main heroine Nagi treats her like The Idiot from Osaka that she is. She does get better, or rather, it's shown that she has her Pet the Dog moments. It's revealed in chapter 90 of the manga that in her year, there were three places for students skipping grades from elementary school to high school. Those places had been awarded to Sakuya, Nagi and Isumi, but Sakuya gave up her place to Wataru so that he could be in the same class as Isumi (whom he has a crush on).
Miki, Risa and Izumi are shown to be examples of this.
Shingo in Initial D is one of these at first. But after an attempt to destroy Takumi's AE86 in a race ends in disaster for him, he develops a change of heart when Itsuki and Iketani take him to the hospital. He remains a Jerk, but his until then almost non-existent heart of gold does shine through more than one. (And, well, his interactions with Nakazatoare funny.)
Sesshomaru from Inuyasha. The guy is a cold-hearted, emotionless killer who tried to kill his own brother simply because he's half-human! It's only when he gets a Morality Pet that he finally starts to care for something other than himself, and that's an understatement. The guy went into hell, of which there is no return, killed the hell god and then purified hell to save the little girl.
Ryouhei Ogawara in Jinki Extend fits this trope pretty nicely; he starts out the series looking like a clear villain, dressing up like a woman and headbutting Aoba in order to kidnap her. He insultingly calls her "Ahobaka" (a nickname made up of two Japanese words for "stupid"). He then starts genuinely hating her after an accident of hers ends up permanently crippling his grandfather. Later, as she matures and becomes more reliable, he starts warming up to her (and "Ahobaka" becomes a sort of term of endearment), but he doesn't quite become a Jerk with a Heart of Gold; he's still quite snide and impatient. He's also often shown to be surrounded by women but never shows any of them any interest.
Both Leon Oswald and May Wong from the second season of Kaleido Star start like this. Oswald is an arrogant French headliner who seems to think because he is the headliner he now runs the Kaleido Stage, and Wong is a bitchy baby diva whose attempts to supplant Sora barely stop short of getting herself adopted by Sora's parents. To their merit, once they do get to see how devoted Sora is to her dreams, they start getting better.
Hibari. The school is his life, and he will bite you to death if you do anything to hurt the school in any way, disrupt its functioning, or really just irritate him.
Byakuran, Xanxus, Mukuro, and Reborn.
Nijima of Kenichi: The Mightiest Disciple, otherwise known as "that guy who could solve all of Kenichi's problems by shutting the hell up and not attracting attention". Although he does have some moments that prove that he's not all bad.
Kururu/Kululu in Keroro Gunsou. He's far more interested in dicking around with anyone and everyone around him, than actually doing anything useful.
Prince Baka from Level E. He constantly trolls the main character and guilt-trips him, plays sadistic games with his own loyal subordinates, and is generally a gigantic jerk on purpose towards everyone purely because It Amused Me: It's so bad that he has interstellar renown as a gigantic selfish jerk. Episode 5 of the anime sees him kidnap a random bunch of schoolkids off the street and forces them to become a sentai team to fight their homeroom teacher (who is a disguised alien, but hasn't actually done anything) for his amusement. When the kids grow wise to his schemes, he instead sics the kids on his own second-in-command (who is completely unaware of the whole thing), as said second-in-command holds the only way for the kids to get the suits off again.
Naru from Love Hina can come across as this at times, especially in the anime.
Arisa Bunnings was initially a bully who was unwilling to consider others' feelings before Nanoha slapped her (her first "befriending") for stealing Suzuka's ribbon.
In one of the StrikerS sound stages, Vita admits to having been constantly abrasive and rude to the rest of the Wolkenritter out of battle during the first Reinforce's existence. She mellowed out somewhat between when Hayate became her mistress and StrikerS, but still has a fairly hot temper.
Precia Testarossa systematically batters and abuses Fate for lack of progress on a mission - she whips the poor eight year old magical girl with a bullwhip! All Fate wanted to do was see her mommy smile again. No matter how much suffering was involved, as long her "mommy dearest" becomes nice again. Too bad, Precia reveals that Fate was just a clone complete with the fake memories of Precia's dead daughter, Alicia, and proceeds to call her a tool to her face, admits to have hated her all along! When Fate is in position to give one last chance for Precia to stand down and repent for crimes, telling her that while not being her daughter, Fate still cares for Precia, who brought Fate into the world. And the queen bitch laughs and chooses to die instead!
Pick any Eclipse infectee outside of Tohma/Touma in Force, but special mention goes to the Huckebein. Prime examples include:
Almost entire cast, save for the protagonist and his love interest.
Notable jerkass-exceptions aside from those two: Grandpa Otonashi, the Godai family (save for Grandma Godai, who can be a jerkass just for kicks), Asuna Kujo (she's just sheltered and somewhat naive... if she's ever being a jerkass, it's entirely unintentional) and possibly Ikuko Otonashi, who isn't able to keep her attention focused on anything for longer than half a minute. Oh, and Soichiro (Otonashi, anways; the dog, most of the time)
Yotsuya takes the cake, though. The entire reason of his existence seems to be making life miserable for others, parasitism, causing massive property damage, hurling insults, mind screwing, and not only never providing the tiniest benefit whatsoever to society but making it a point not to, and flaunting it.
The title character from Nadia: The Secret of Blue Water comes across like this for scenes where she loses her temper and says nasty things to Jean and occasionally Nemo (both of whom obviously don't deserve it). Nonetheless, she does apologize numerous times to Jean for her outbursts and does something reconciliatory (e.g. comforting him about his father, bringing him something to eat, or going on walks with him) but she never gets to do so with Nemo, until she realizes, too late, that she could have been nicer.
Neji Hyuuga is introduced as this, looking down on those he saw as weaker than himnote Virtually every genin-level ninja, but especially Lee, Hinata and Naruto until Naruto beats it out of him. Before this happened, the nicest thing we have seen him do is offer his cousin a chance to surrender before their match. And then, for all intents and purposes, he tries to kill her and only fails because the adults in charge are quick enough to jump in and stop him. And then he has the audacity to get upset and cry favoritism when they stop him from essentially murdering his defenseless cousin.
Kurenai: (thinking while looking at Hinata) Oh no, she's going into cardiac arrest... (glares at Neji) Was he really trying to kill her?
Neji: (smugly) I wouldn't waste time glaring at me when you really should be taking care of her.
When he isn't killing everything in sight, Hidan is a godawful fucking dick to everyone he's not supposed to kill. For example, he taunts Team 10 and their dead sensei, whom he killed in order to provoke them.
Madara Uchiha. Or, more specifically, both the real Madara Uchiha and Tobi/Obito Uchiha. The former is exceptionally arrogant and enjoys talking down to his opponents. The latter launched a deadly attack at Naruto, and when Neji ended up dying from Taking the Bullet for him (as well as for Hinata, who was also planning on doing so), he mocked Naruto for failing to live up to his promise not to let his comrades die.
The real Madara Uchiha is such a dick that not even Kurama, the nine-tailed fox, can stand him. The moment the man came on to the scene, Kurama immediately initiated an Enemy Mine with Naruto, who he has served as an Enemy Within for most of the series. It's to the point where one could easily argue that anybody halfway decent and had the displeasure of meeting him hates his guts.
Chief: Fool!!!! I had eight... UNTIL YOUR FATHER KILLED THEM! We took pity on the baby... it was dumb luck that saved you. Now you're a friendless, sullen brat.
Naruto: If friends are so important... why don't you go join yours?
Asuka Langley Soryu of Neon Genesis Evangelion is practically the epitome of a jerkass who regularly announces that she hates everyone and everything at times of emotional intensity (which is mostly when she fails due to her own fault and tries to blame it on something else). She is not even trying to be playful or joking when she says she hates people; she almost always means it, especially in the case of Shinji or Rei for merely not being nice to her, despite the fact that they did absolutely nothing to deserve it; in other words, she hates them just for being there. There is a good reason for this, though: like all the main characters, she has an extremely traumatic past, which has instilled her with a severe inferiority complex, for which she compensates by aggressively attempting to keep the people around her from getting too close to her, as she does not want anyone controlling or pitying her.
Ryoji Kaji starts off as quite a jerkass himself, coming off as completely self-centered and his behavior toward Misato borders on sexual harassment. He's even introduced in the same episode as Asuka is, and while his debonair demeanor is more pleasant than her's, his actions for his first few episodes actually surpass her in sheer jerkassery. Once he and Misato's past together is uncovered and a misunderstanding between them cleared up, he drops the Jerkass Façade and reveals that he's actually more of a Jerk with a Heart of Gold.
The eponymous character of Niea_7 is a lazy, loudmouthed freeloader who seems to care so little about other people that it sometimes crosses into full-fledged sociopath territory. Why the other characters put up with this is a mystery; strange enough, it's the other aliens who have the most trouble with her. Human Mayuko seems to genuinely care for her, despite their differences.
Wapol. While every other Big Bad has a fundamental goal or Freudian Excuse when they do what they do, Wapol doesn't have any, other than to be the king of Drum Island, and he was born to the throne. He partakes in acts of cruelty, most notably gathering up twenty of the island's best doctors, for which it was famous, and then banishing all of the rest just because he wanted the citizens to beg him to let them see one of the Twenty, and also because he could, and there was still no guarantee that he'd let them. This is just the start. He did get some Character Development in the side story title pages, however. He was hungry and tried to eat garbage and reshape them into toys to keep him entertained, except kids loved them so he started selling them to everyone. Then he made a factory, married a model, and was last seen doing some good in the world. Actually, it seems that he's turned into a full-blown Corrupt Corporate Executive, as the final chapter of his cover story was entitled "The Rebirth of Evil". And now he's once again the ruler of his own country, called the Evil Black Drum Kingdom.
As shown in recent flashbacks, Arlong seems to have always been a Jerk AssAnti-human racist. Fisher Tiger's death and his stint in Impel Down just made him even worse.
Sanji has been called a jerk on occassion due to treating the women members of the crew better than anyone else, but when it comes down to it he'd gladly give his life if it meant saving his friends and other innocents regardless of gender. So more of a Jerk with a Heart of Gold than a real Jerk Ass.
While James and Meowth have been played sympathetically many times since their first character development episodes, Jessie has always been the "nasty one" of the trio and doesn't get many episodes to herself. To her credit, she has had Pet the Dog moments, like when she let Dustox go away to mate or her bond with a certain Blissey...but these are somewhat sparse.
There's also Ash's Sinnoh rival Paul...whose methods of training make Kanto Gary seem tame by comparison. This was so bad even Jessie was appalled by it.
Dawn's rival Ursula was also pretty bad, she was a total jerk from the very beginning and her arrogance made her especially annoying.
Being the character Paul was based on, Silver is also this in the GSC chapter of the Pokémon Special manga. Both go through a bit of character development.
Unova rival Trip didn't really care about Pikachu currently lacking access to its Electric attacks, though he's a bit more friendly than Paul. However, this is subverted later when he has more of a Jerkass Façade as shown when he does care about Ash's Pokemon as saving Ash's Pidove from Venipede that attacked her and then later telling Ash that his Oshawott needs to open his eyes when using Aqua Jet.
The Black and White series also gives us Burgundy and Georgia, respectively the rivals to Cilan and Iris. To be fair, Burgundy isn't that dislikeable, because despite her obnoxious attitude, she is too much of a screw-up to be taken seriously. Georgia, on the other hand, spent her whole time onscreen being a bitch to both Cilan and Iris. And it is also hard to get mad at Georgia when her rival is almost if not just as rude and petty as her. Iris herself may or may not be a jerkass but the fact of the matter is in her very first episode as part of the main cast she insulted Ash for getting knock on his ass by Patrat when he was pre occupied with Deerling, and she acted condescending towards Ash in many episodes by calling him a "kid". The two of them get bettereventually as shown during the Dynomite arc.
Gary Oak from the original saga, who spent most of his appearances taunting Ash. He becomes less of a jerk as the series goes on, and by the end of the Johto arc, a lot of his Jerk Ass status is more or less gone.
Harley, the Pokemon Coordinator, from the Advanced Generation is a jerkass towards May and her friends. He manipulated a naive Max into telling an embarrassing story about May to air it while May was competing against him in a competition. He also manipulated May with "tips" to help her win a competition, only to be exposed by Drew for his stunt.
Jin Akutsu is a big, scary jerkass who hits people from other teams, treats his mom rather badly, humiliates his childhood friend when he attempts to call him out on his jerkiness, almost hits his coach when the old man tries to recruit him, and in flashbacks he picks on other guys several times. Still, after losing his official match with Ryoma he evolves more into a Jerk with a Heart of Gold.
Ryoma Echizen himself is already a big jerkass to start with, frequently taunting his opponents with the phrase "Mada mada dane (You still have a lot to learn)". In fact, Prince of Tennis is ripe with jerkasses, including the narcissist Keigo Atobe.
Lilie sometimes gets dangerously close to this trope. When she's first introduced, she merely seems a little gossipy and quick to assume the worst. But by the second season she's downright sadistic, to the point where she tries to push two friends into a fight over a boy, and freaks out when they tell her they're too good of friends to fight. In fact, most fans consider her sadistic to the point of comparing with Drosselmeyer, the series' Big Bad.
Everyone in Ranma ½ has fallen into this at least once.
Remote: The novelist, Maria Ishizuka manages to rub almost everybody at the hot springs spa the wrong way very quickly. Later on, the motive for her murder is that she used a friend's sister's disease as the basis for a best-selling novel, driving the sister to suicide and her friend to murder her.
And the male members of the Wong family seem to be more-or-less decent guys. Kinda weird, but nice. Which is ironic, considering they're a 'family' in both the blood-related sense and the Mafia sense...
Makoto Ito from School Days starts out as a fairly typical loser protagonist only to turn into one of the biggest jerks of all time by the end of the series, first cheating on his girlfriend Kotonoha with his classmate Sekai, then cheating on her with most of the rest of the female cast - and, when Sekai reveals that she is pregnant with his child, Makoto ditches her for Kotonoha. It does not end well. He isn't as much of an asshole in the OVAs or the spin-offs though.
Hatori from Sekai Ichi Hatsukoi mainly due to his yandere tendencies that seems to extend not just to his rival Yanase but also to Chiaki (his boyfriend) and to a certain extent Ritsu. (Kisa and Mino like to pick on Ritsu too but given his yandere tendencies, it's probably intentional unlike Kisa who admits to like teasing Ritsu since he's the newbie.) Some of his actions include brutally raping Chiaki, constantly harassing Yanase for being near Chiaki and almost beating the shit out of him in his own house after Yanase breaks down from being rejected by Chiaki a second time.
Sekirei has quite a few characters with a serious case of jerkassery, on both sides of the morality spectrum.
The Sahashi women are both enormous jerkasses, which probably examples why Minato is such an Extreme Doormat. Mother Takami enjoys being a Troll, while little sister Yukari regularly kicks men in the balls if they annoy her.
Izumi Higa is probably one of the biggest examples in the series, being a Smug Snake that mistreats his own Sekirei and blackmails Uzume and Shiina into working for him. He has no problem doing anything necessary to get what he wants, whether it's forcefully winging Sekirei against their will or ordering assassinations.
Seo and Hikari both fall into the Hidden Heart of Gold variation, balancing their jerkass tendencies with kinder moments. Miya can also be quite the jerkass, but is skilled enough at Passive Aggressive Combat to make it easily missed.
Zelgadis Graywords of the Slayers franchise, though only in the original novel series. It really doesn't help that he was shipped off without any justification after the first eight novels were over. ''Gourry'' showed scant shades of this trope in the novels; justified because he isn't The Ditz in that media.
Dr. Eggman in Sonic X. Lampshaded in the final episode of series 1, where he's yelling for Sonic over a microphone (keeping everyone in the forest up at an unreasonable hour) he says 'This world will have to face the music!' before disco lights come on in his ship and he starts doing a dance that his robots call 'The Jerk'.
Excalibur from Soul Eater is an absurdly powerful being, his weapon form once wielded by King Arthur. But his fame seems to have gone to his head, turning him into an insufferable jerkass, with a list of 1000 rules you must follow if you want to wield him. Yes, 1000. On the other hand, it's hard to tell how much of this is intentional. Excalibur spends most of his time being too incoherent to give the impression of intentionally being a jerk, rather than just obnoxious as a result of his eccentric personality.
The agents of the O'Hara Foundation tend to act this way towards Ray Steam in the movie Steamboy. By the end, it seems that they're trying to kill him out of sheer spite, despite having no particular reason to do so and much, much better things to do with their time (such as trying to escape the giant, flying steam-powered castle that's about to self-destruct around them).
Miu from Strawberry Marshmallow, to whom the other characters respond accordingly. Cutting to Miu lying face down and sprawled after a Jerkass moment is a Running Gag of the anime series.
In the OAVs, Princess Ayeka's petty rivalry with Ryoko was a humorous chink in her formal armor, deflating her pomposity. Through several TV series — especially Shin Tenchi Muyo (Tenchi In Tokyo in the US) - made it so noticeable that she became rather ditzy.
Ryoko pushes this, especially in the TV adaptations. Many times she goes after Tenchi just to provoke Ayeka, including when Ayeka and Sasami were about to leave Earth forever. She once left the entire team to almost starve to death in space when she spent the money that was supposed to buy them food on partying. However, even in her more selfish adaptations, she still truly loves Tenchi and proves under tougher circumstances to be more of a Jerk with a Heart of Gold, especially by the time period of the third movie (set in the first TV series timeline) in which she and Ayeka still haves squabbles, but now live together and actually respect each other.
Tenchi in Tokyo ramps this up towards everyone. In fact, it seems like the anime's entire plot hinges on the idea that everyone has to be complete assholes.
Eguchi in Wa Ga Na Wa Umishi isn't content with being an arrogant genius. No, he's gotta go out of his way to ruin other people's efforts as sneakily as possible just so he can keep being better than them. Even his bosses don't like him, even though he's their best worker.
Kirisaki Yuichi and Yukino Azusagawa of Yakitate!! Japan. To the point where they're like terrorists.
Yanda from Yotsuba&! seems to genuinely enjoy picking on a five-year-old girl. Koiwai probably wouldn't have anything to do with him if he had a choice (he doesn't; Yanda is his kohei and thus he's socially expected to let him hang around). As it stands, Yanda does get put in his place - a lot.
Seto Kaiba starts out as this, forcing Yugi's grandpa to duel and mocking anyone, especially Joey, who he considers beneath him in terms of dueling skills.
Weevil Underwood, an annoying little dweeb who is willing to do anything to get ahead of the competition, from asking Yugi to see his Exodia set in order to chuck it overboard to finding out about the tournament rules before anyone else.
Bandit Keith is like the above, only worse. When Bones fails to beat Joey in a duel, he not only has his cronies block the exit to a cave where Yugi and Co. are in, but beats the crap out of said cronies and steals their star chips.
Many of the opponents that Gash and Kiyomaro encounter in Zatch Bell! are assholes, though some more so than others. While it's a given they're all just doing whatever they can to become King of the Demon world, some are just unforgivable. Zophise in particular robs that whole damn bakery.
Zero no Tsukaima: So far it's shown nobles of Louise's world are this, including our pink haired main character, although there are exceptions but too few. Louise herself comes off as such a bitchy, whiny and violent Tsundere that her antics against Saitou are less funnyandmore disturbing as time passes.