Erfworld gives us Prince Tramennis and, to a lesser extent, Foolamancer Jack Snipe. Justified in Jack's case. He's a Foolamancer. It's his job to see the world as it is so that he can manipulate it. Prince Tramennis is just balancing out the rest of his family.
Every main and supporting character in both Michael Poe's Errant Story have their moments of this, but the males seem especially prone to it. Jon and Ellis probably have a Snark/Strip ratio of 2:1.
Harold Eastwood:(on Virus smoking in his intro page) You mean it was a lame attempt to look badass. Syrus "The Virus" Zuviel: Did it work? Eastwood: No, you just looked like a regular ass. Virus: Ha. And indeed, ha. Don't quit your day job Harry.
Most of the cast of Fletcher Apts except for Kia and Mr.Fletcher.
Daniel from Footloose, which can result in his receiving a smack (or boot) upside the head from his twin sister Jin.
So, so, so many examples from Homestuck. Just within the main characters, Dave, Rose, and occasionally John all qualify, and beyond that, practically half the cast qualifies. There's a reason the verbal competition between Kanaya and Rose is measured by the "Flighty Broads and their Snarky Horseshit-o-Meter." And that said "Horseshit-o-Meter" explodes.
Rayne of Least I Could Do goes so far over the top with the Idiot Hero and Handsome Lech routines that most of the rest of the cast are divided into those who can use deadpan snarking to survive his bombastic ways (Issa and Noel), and those who turn into his punching bags (Jon and Mick). Noel is probably the best example.
Artax: She Who Must Not Be Named has taken That Which Man Was Not Meant To Know! Nodwick: Did she say where She Who went? Artax: To The Lands Which Know No Name! Nodwick: Uh-huh... let me know if we find any proper nouns in all this mess.
Crystal: Arrgh! You little twit, I'm gonna kill you! Belkar: Yeah, and I'm going to drop a house on you and sing about how I represent the Lollipop Guild. C'mon, let's keep our threats realistic, shall we?
Redcloak: I'm on my way to finish zombifying the monsters we killed up in the tower. MitD: Yeah, I can help with that. Redcloak: Really? So, I guess those three boxes of mallomars you finished off somehow earned you enough XP to gain 5 levels in cleric overnight. MitD: Well, they were especially chewy.... Redcloak: Then unless you are volunteering your services as raw materials, I don't think you are going to be much help.
Captain:(in front of a computer with a destroyed monitor) Hello computer... I'd like one free internet please. Maybe if I twiddle these wires... Mr. Snippy: You are an idiot. Captain: What? No... Why? Mr. Snippy:(holding up a cell phone with a destroyed screen) To illustrate, I shall take a photo of your epic failure with my phone.
Ruby, in Sticky Dilly Buns, has a bumpy start as a snarker, being too neurotic to manage the deadpan well and living in a fairly snark-light comic. However, by this strip it seems that she's beginning to develop the skill. The male disguise may help her relax enough, but mostly it's the golden opportunities that she's offered; the comic may turn out to be about the creation of a competent snarker.
Cassie, Chris and Alan are all snarkers in Sunstone.
Also many people in another of the author's comics, Super Stupor. Come to think of it, perhaps every character R. K. Milholland creates. And thus, probably Milholland himself, as well.
Bert and Darby from TRU-Life Adventures are the most consistently snarky among the toy store staff, but almost everyone working there gets a moment. It must be a survival technique for dealing with the customers.