Lucy is sweet, dorky, excitable, and appears to have the mind of a child at times.
The Minions are 10,400 cuddly, accident-prone, small, and yellow humanoids that you want to hug all day, to the point they became Breakout Characters.
Margo gains some tendencies in the sequel when she gets her first crush. Much of her behavior around him is so awkward it's impossible not to love.
Alternative Character Interpretation: Did Mr. Perkins set Vector up to steal the moon instead of Gru to help his son remain the most successful villain, just to spite Gru, or to help cover the loss of money loaned to Gru, considering how he mentions how "lucrative" stealing the moon would be, not to mention him seeming legitimately unconvinced that Gru could pull off the heist?
Base-Breaking Character: The minions are either the best or worst parts of the franchise, based on how much (or how little) you enjoy their brand of physical comedy. The fact that they have spawned many copies only adds fuel to the fire.
Big-Lipped Alligator Moment: After Gru steals the moon, a werewolf turns back to normal. This is the only supernatural element in any of the three films, by the way, and doesn't really fit in other than being Played for Laughs.
Crack Ship: An odd case with Margo and Vector. At most, Vector is 10+ years older than her in terms of age. Not mention that he kidnapped her and her sisters and planned to keep them for who knows what.
Crossing the Line Twice: Most of the visual gags qualify as a child-friendly version of the trope. A rocket landing on a playground? Not funny. A rocket landing on the spinner thing causing it to spin incredibly fast while the children cheer? Hilarious.
Ensemble Dark Horse: The minions. The studio saw this coming, and gave them featured roles in all the promotion. Kevin and Dave in particular.
Esoteric Happy Ending: Barring the possibility that Miss Hattie was simply too pissed off with Gru over his insulting her in Spanish to bother with any formalities, let alone verify who called to return the kids, between the climax and the epilogue with Gru and the kids which serves as the happy ending there had to have been some legal proceedings between Gru and Miss Hattie over custody of the kids which, for all the film's irreverent humor and Getting Crap Past the Radar, Illumination Entertainment apparently decided weren't worth depicting.
"Funny Aneurysm" Moment: The film has a bank that invests in supervillany. Two years after the movie's release, it was revealed that HSBC had been knowingly laundering money for terrorists, drug smugglers, and tinpot dictators the world over.
The Minions are also massive in the Philippines, and there are even claims that some of the gibberish they mutter is actually Tagalog.
The franchise is also big in South America. In the countries on that continent, whenever a new Despicable Me film comes out, it will usually top the box office for at least three weeks. The Minions spin-off is also the highest-grossing film of all time in Chile.
The minion's cheering for Gru in their first appearance is a lot nicer after seeing their struggles to finding a boss and meeting Gru as a child.
In the first film, Kristen Wiig voices the cruelMiss Hanniganexpy Miss Hattie, who despises the girls and does everything she can to make their lives with her miserable. As the character doesn't appear in any of the sequels, Wiig was recast as Lucy Wilde, who loves the girls just as much as Gru does.
There have been some comparisons between this and Megamind; showing a Villain Protagonist, his loyal minion named Minion, and then finding a love interest (which didn't happen to Gru until the sequel). Then in 2016, Universal, owner of Illumination and Despicable Me, acquired rights to DreamWorks Animation—the studio that made Megamind.
The way Vector introduces himself to Gru is...either very socially awkward, a bad attempt at flirting or both.
It's Popular, Now It Sucks!: The Minions are a source of bile in various circles for all of the popularity and overuse they have gotten. In Minions and in Despicable Me 3 they were accused of ruining the franchise and stealing the spotlight that should have gone to Gru and the girls.
Jerkass Woobie: Gru himself qualifies as this. Sure, he's a mean guy, but look at all his flashbacks to him as a kid with his mom dismissing his claims that he'll go to the moon (and not being encouraging overall to begin with) and the utterly crushed looks on his little face. Not to mention his reaction to his adopted girls been taken away to keep it from being a distraction to him.
The sequel also revealed that Gru was a social outcast in school. The other kids completely avoided him and feared that if he touches them, they will get "Gruties." Seeing his heartbroken expression from this is just agonizing.
The minions. Somehow, they've mutated from a Mascot Mook to the symbol of "Facebook wine moms" everywhere.
Gru's presentationExplanation Gru presents a slideshow to Mr. Perkins in an attempt to get funding for his scheme, with the girls messing with the third part. "I fly to the moon... I shrink the moon... I sit on the toilet... with-- what?)". This has been snowcloned to hell and back, most commonly having someone do a double-take at a blatantly idiotic third step of their plan.
Hella Gay Explanation Commonly on Reddit and Discord, images of Gru have been used to call other users "hella gay" depending on their positions in posts. Many variations have spawned, examples including "Ultra Gru", "Infinite Gay", and Cuphead's "Triple Gay" meme.
"Seinfeld" Is Unfunny: The Minions were lauded as the movie's funniest characters and became the series' Ensemble Dark Horse group. This, of course, wound up leading to other companies wanting a piece of the pie and coming up with their own Minion-like characters themselves. (i.e. McDonald's Happy Meal creatures, the elves in Dreamworks' Rise of the Guardians, and the lemmings in Norm of the North, etc.) The verbally-impaired-friends/helpers-of-the-protagonist trope has seen so much use that anyone who went back to watch the movie that broke it into the mainstream will likely fail to see the appeal of the quirky Minions.
Ships That Pass in the Night: Justin, the rambunctious kid from the movie's opening, is a decent match for Edith, given their love for destruction and mischief. However, they don't interact at all, Justin is never seen again after the opening, and they presumably live in different countries.
The revelation that Vector is Mr. Perkins' son doesn't really amount to anything aside from Vector finding out that Gru stole back the shrink ray. This is made even more jarring by the fact that Perkins does not appear any later in the movie. Or even in any of the sequels, either, where it would have made perfect sense for him to return with a larger role.
Most "villain becomes a hero" stories have a hero to rise up against them. Wreck-It Ralph had Fix-it Felix, and Megamind had Metro Man. This movie doesn't appear to have any hero to rise up against Gru. Law enforcement is mostly lacking in this universe, and the Anti-Villain League wasn't introduced until the sequel, where Gru gives up villainy entirely.
Uncanny Valley: The CGI is noticeably more rubbery here than in the sequels, causing some character designs to look plastic and kind of weird looking at times. Possibly justified given this was Illumination's first movie.
Viewer Gender Confusion: Due to her short hair (at least compared to Margo and Agnes), deep voice and general tomboyish behavior, it can be pretty easy to mistake Edith for a boy.