- The one that started it all: "Maybe" by the Ink Spots, which perfectly fits the opening and ending of Fallout.
- "Metallic Monks". A haunting, eerie piece that combines an air raid siren, Morse code-like beeping and faint male chanting to create a bleak, foreboding sense of exploring a devastated nuclear wasteland. "Immersive" does not do it any kind of justice.
- The relaxing alternate world map theme that plays when driving the car, "My Chrysalis Highwayman". It's a shame that you won't hear it very often since you'll probably reach your destination before the intro is finished playing. Of course, you don't need to leave the map screen immediately after you arrive at your destination
- "I Don't Want to Set the World on Fire," especially if you take its lyrics and apply them to the events of the game.note
- Many of the songs from Fallout 3 are deliciously ironic. "Let's Go Sunning" comes to mind.
- And for sheer catchiness, "Butcher Pete". Which is now stuck in your head and will be for the next fifteen hours. You're welcome. Even better if you're using a knife to attack opponents.
- Also notable for getting stuck in your head and refusing to leave: "Bongo, bongo, bongo, I don't wanna leave the Congo, oh no no no no..."
- And not just songs, soundtracks are awesome too. Take "Battle 1" playing when fighting a Super Mutant Behemoth with a Fat Man. And "Battle 5", which is actually titled "Behemoth" on the soundtrack.
- There are few things more satisfying than roaming the Wasteland and blasting the monster's heads while listening to Cole Porter's "Anything Goes". Soundtrack Dissonance at its best!
- This game is not without its Ear Worms. See: "Jingle Jangle Jingle", "Something's Gotta Give", and "Ain't That A Kick In the Head".
- The main theme. Really fits the western feel of the game.
- If ever there were a song to make headshots by, "Big Iron" is it.
- "Lone Star" is always a good one to listen while roaming the Mojave Wasteland.I know my home is waiting for me by the river shore!
I know that all the ones I love will welcome me once more!
In dreams I see them now, though it seems I'm bound to roam
My thoughts are still of Texas and of Home!
- "Dam Nation", the Final Dungeon theme. The song has a heavy beat as the drums of war are struck as both the NCR and Caesar's Legion fight high above the Colorado.
- "Blue Moon", The first song that plays in the game, has the classic Vegas feel to it.
- "Begin Again", featured in the Dead Money expansion pack, is a haunting song that espouses the main theme of the Sierra Madre - letting go.
- The main theme is very atmospheric and packs some serious punches. An epic rock cover made it more wild with guitar riffing.
- "Rebuild, Renew" and "Of the People, for the People", two of the city themes, both of which convey the feeling of a wasteland society that is rugged, but with hope for rebuilding.
- "Still Standing", one of the Minutemen themes, which strikes just the right chord between hopeful, militaristic, and heroic.
- The Institute's theme ("Imagine Utopia"), which has a fittingly futuristic and hopeful sound with an also fittingly sinister, mysterious, and apprehensive hint to it.
- "Dominant Species", one of the combat tracks, is an epic remix of the main theme. There's a good reason it was used for the game's launch trailer.
- "The End of the World" by Skeeter Davis. A somber song that greatly fits the apocalyptic setting and the Sole Survivor's situation.
- "Atom Bomb Baby" is a great song to listen to while wreaking havoc in the wasteland.
- "The Wanderer" by Dion & The Del Satins. Fairly catchy on its own, but it also acts as an ironic, and tragic, contrast to the main character's situation. It adds to the emotional depth of the game.
- Lynda Carter, who voices the Third Rail's lounge singer, Magnolia, recorded some fantastic songs for the game, like the upbeat "Baby, It's Just You" or the sultry, innuendo-laden "Good Neighbor"
- "Rise and Prevail" is one of the more epic combat tracks, perfect for taking out Raiders and Gunners to.
- "Uranium Fever" by Elton Britt. This song is really catchy, and will now be stuck in your head for a damn long time.Uraaaanium fever has done and got me down
Uraaaanium fever is spreadin' all around
With a Geiger counter in my hand
I'm goin' out to stake me some government land
Uranium fever has done and got me down!"
- The Nuka World theme is delightfully cheesy and caricatured for a theme park jingle, and as always gives off the skewed disconnect between Pre-War America and the horrific Raider-infested reality.
- All of the Far Harbor soundtrack, but most notably "Our Island". It nails down the lonely, desolate tone and mysterious atmosphere of the DLC perfectly.
- "The Children Of Atom" has both a haunting tone along with ethereal echoing Gregorian-style chanting, as if one of the Children of Atom is singing a hymn to their holy god. It has a very foreboding feel to it and even calls to mind "Acolytes of a New God" from Fallout. Really makes you realize how those silly kooks in Megaton aren't just whistlin' Dixie anymore, huh?
- The Filk Songs are also worthy of mention.
- First and foremost, there's "Going Nuclear" and "Some Things Never Change", both from Miracle of Sound. The first is an upbeat swing piece about the singer "going nuclear" out in the Wasteland and having fun, while the second is a much more somber piece about the state that the world has fallen into and how the Sole Survivor is perceiving it through the filter of their Pre-War life. Both greatly fit with the story's themes and tone - "Going Nuclear" sounds like it could be heard right after "Baby, It's Just You" on Diamond City Radio, while the somber and tragic tone of "Some Things" would fit perfectly with the background OST. "Some Things" also carries several stylistic choices and a lyrical callback to his earlier piece for Fallout 3, "Beauty Bleak."
- J.T. Machinima's incredible "Welcome To My Apocalypse," which more or less consists of an epic Boastful Rap from the Sole Survivor as they tear through the Commonwealth like a hot knife through butter, bragging about their numerous acts of badassery while trying to rebuild their lives.
- Dan Bull's SPECIAL Rap, which lays out each SPECIAL stat with plenty of Added Alliterative Appeal, all backed by an instrumental that sounds like it came right out of the '50s.
- The absolutely gorgeous cover of Take Me Home, Country Roads by John Denver used in the game's reveal trailer. The original was one of Denver's Signature Songs and one of the official state songs of West Virginia for a good reason, but the cover by a features a baritone lead singer which makes it noticeably different from the Denver original. The full cover was eventually released on iTunes, and you can listen to it here. The song was used as a fundraiser for Habitat For Humanity.