Well, he does lift Scooby and Shaggy with one hand at least twice. So he has the strength for it... he just tends to borrow his strategies from Leeroy Jenkins.
Scooby-Doo, Where Are You! The original Scooby Doo's Velma was definitely this. Although she's the shortest member of the gang, she can carry all the rest of the gang and run from the monster at the same time.
In the 1940s Chuck Jones directed a handful of shorts featuring an African pygmy warrior named Inki. Also appearing in these cartoons was a small, black mynah bird who walked with a signature series of rhythmic hops and skips to the tune of Felix Mendelssohn's "Fingal's Cave" overture. The instant any attacker followed this bird around a corner (or otherwise out of the audience's line of sight), the sounds and music of a serious fight would ensue for approximately ten seconds, followed by the bird continuing on his way with nary a feather out of place. The attacker(s), on the other hand, were usually battered rather severely. To give one example, in the short "Caveman Inki", which was set in the stone age (described in the introduction card as being "probably before any of you people were EVEN BORN!"), the world's first last and only carnivorous brontosaurus was tied into several knots.
There was also Rocky the gangster, of "Rocky and Mugsy" and a few other Bugs Bunny shorts, who despite being a tiny man could easily beat up people much bigger than himself.
Kid Banty the boxing rooster from the Foghorn Leghorn cartoon "Sock A Doodle Doo".
Mickey Mouse. Though not always victorious in his fights, Mickey has been known to jump into battle with much larger foes—Pete most often, but also the occasional monster spider (Gulliver Mickey, 1934), crooked Indian chief (Pioneer Days, 1930), or crew of pirates (Shanghaied, 1934).
Donald Duck. Many times, his strength isn't just due to his Unstoppable Rage, but also sheer determination. In the Quack Pack episode, "Ducks By Nature", the camping leader is jealous of Donald and calls him "city wimp" but Donald carries BOTH their camping equipment (which includes a CANOE!) and then the camp leader challenges Donald to a race to climb up a cliff. Then, he cheats by secretly tying Donald to a tree with an EXTRA-STRONG bungie cord. Donald struggles for a bit before his determination makes him so strong that he not only uproots said tree but literally SENDS IT INTO ORBIT and gets him to the cliff top faster than the camp leader! In "Bird Brained Donald", he lifts a metal rail in from its post in cement to use as a ladder! And he beats BOTH Mickey and Goofy in a pseudo tug-of-war in "Answering Service". And these are just a FEW examples!
Droopy Dog. Usually, his tactic is psyching his opponent out, or letting him beat himself up; but when push comes to shove, Droop will face down his foe, tell him "You know what? That makes me mad", and proceed to beat the ever-living crap out of him.
In the short "Droopy's Double Trouble", the audience is introduced to Droopy's stronger twin brother Drippy. The plot revolves around Spike running into Drippy (who has been instructed to keep out all strangers) and wondering why Droopy keeps beating him up for no reason.
Then in "Homesteader Droopy", his infant son ultimately thrashes the bad guy.
In the Tom and Jerry cartoon "Jerry's Cousin" the titular cousin is called Muscles Mouse, and the cats where he lives live in fear of him.
Jerry himself becomes a Pint-Sized Powerhouse after a poison concocted by Tom backfires and gives him superstrength in "Dr. Jeckyl and Mr. Mouse".
And in "The Milky Waif" Jerry becomes this after Tom starts picking on his little nephew and triggers his Papa Wolf instincts.
Stewie Griffin of Family Guy. Still a baby, but he can hold his own in a fight against Osama bin Laden and Lois in "Lois Kills Stewie", almost killing her if it wasn't for Peter's arrival.
Meg also has shades of this, in one episode she beat the crap out of a guy when he rammed into her car.
Brawn is one of the smallest Autobots (a little shorter than Bumblebee), but he's got muscle and attitude far beyond his size. Some of his exploits include picking up Soundwave and Megatron and tossing them like rag dolls.
Soundwave's Cassetticons (and later series' versions of those characters) can get pretty Badass for their size. The one everyone knows is Rumble: Human-sized, but able to shake the ground and bring giant-er bots down to Earth, as well as being able to hit as hard as any car or truck-bot. The one who takes the cake, is the Marvel comic's version of Buzzsaw, though. You probably don't remember the bird guy who was like Laserbeak but yellow if you've only seen the show, but in the comic, they were quite different characters. Laserbeak's job was a scout and spy, whereas Buzzsaw's job was to kick serious skidplate. The little guy had a habit of not just holding his own against, but curbstomping full-size bots. He considered himself an "artist" and his idea of a masterpiece was Autobots who'd been trashed with what he considered great precision and what everyone else considered "Holy Primus did he just take down OMEGA SUPREME?!"
The Transformers Prime incarnation of Laserbeak is the baddest yet. Definitely a case of Crouching Moron, Hidden Badass, he hardly seemed a character in his own right, deployed on extremely rare occasion to be Soundwave's eyes and ears and never being referred to by name. Then came Triage, when Soundwave left the dogfight he'd gotten into with Wheeljack's ship to Laserbeak. Minicon-sized bird-bot versus building-sized ship piloted by a Badass Wrecker; who would you bet on? In fact, Laserbeak brought down the Jackhammer alone and only took one hit. (The one hit, though, was enough to keep Laserbeak down long enough for Ratchet to hack him and get at some Decepticon secrets, but still, damn. Even so, by the end of the episode, Laserbeak was still mobile, and easily fixed. Not so the Jackhammer.)
Of course, don't think the Autobots can't pack a lot of mean into a little a space, too. One of Blaster's tape buddies was a rhino called Ramhorn, and he could tackle down any full-size 'con and boasted hip-mounted rocket-launchers (three missiles on each side.) Now, if only he could do something about that awful stutter. Of course, nobody who's smart gives him any crap about it...
Garfield, normally not averse to eating live birds like he is to eating mice at all, is afraid to get near Ludlow, a small bird who is naïve and kind of annoying. However, he is not (known to be) this trope, or the reason Garfield's afraid. Ludlow's father, on the other hand, packs quite a punch, and while he's bigger than his son he's quite a bit more literally pint-sized.
In another episode, one mouse's mother is inadvertently trapped in a cookie jar. He won't believe Garfield hasn't done anything with her, but since Garfield doesn't know what did happen, he's powerless to prove otherwise. This proves dangerous, as the mouse brings over a murine parody of Arnold Schwarzenegger to beat a confession out of him. The Cup-Sized Powerhouse knocks him around a while before Garfield is able to discover and subsequently produce the missing mother mouse.
In Teen Titans, Starfire is tall, but quite scrawny (though really, everyone but Cyborg is, so maybe it's down to the art style), which makes it all the more hilarious when she gets dangerous and introduces villains to the full wrath of a starbolt-wielding Flying Brick.
Klockateer Number 216 from Metalocalypse is a very small member of dethklocks bodyguards but he is a very strong and capable fighter.
Rarity. Unicorns aren't known for their strength, but she can drag carts full of gems with ease, and even carries a large boulder twice her size on her back.
Pound Cake is a pegasus that can haul ponies twice his size while zooming through the air... and he's ONE MONTH OLD!
Meap the alien from Phineas and Ferb. He's a tiny white snowman like alien with big blue eyes and a pink bunny ear hat, but is able to beat up opponents many times his own size and he is actually a police officer on his planet.
Agent Perry the Platypus too.
Also there's Agent S aka Sergei the Snail, who despite his small size and lack of limbs can somehow toss Doofenshmirtz around like it was nothing.
Nova from Super Robot Monkey Team Hyperforce Go!. She's a cute two-foot-tall cyborg monkey who can instantly transform her hands into huge Power Fists that will knock any monster silly, as well as give her a monster grip. Back that up with what may be centuries worth of martial arts training, and you've got one Cute Bruiser who will never disappoint.
From the Justice League Unlimited episode "Dead Reckoning": Some of Grodd's legion of super villains under Lex Luthor's arrive at a Buddhist temple. They encounter a child monk, maybe ten or twelve, who tells them that they cannot enter. Lex sends the Atomic Skull, one of the largest henchmen he brought, to deal with him Skull tells the young monk he won't go easy on him just because he's a kid; the boy responds that he won't either, and proceeds to kick Skull's ass.