Adaptation Displacement: Subverted. At the time, the film adaptation overshadowed the graphic novel, and the comic became more famous for having been made into a film (people were still working out that non-superhero comics even existed). Since then, the graphic novel has become an artform equally as visible as the prose novel, and Ghost World remains a defining work in the medium. The film adaptation has in hindsight become a minor (if still highly regarded) work in the '90s indie boom, and more famous for its link to the novel than vice-versa.
Granted, it ends tragically, but the whole subplot with Coon Chicken Inn poster still looks even harsher once you've seen that commercial alongside other racist ones in C.S.A.: The Confederate States of America.
Enid and Becky slowly drifting apart as they realise they have not much in common - Enid in particular being afraid that adult life is going to suck. Thora Birch's acting career would go downhill thanks to the antics of her Stage Dad, while Scarlett Johansson's would take off.
Hilarious in Hindsight: The blue and green eyeball that Enid is seen sketching in her art class early in the movie is strikingly similar to the logo that Jacksepticeye would start using more than a decade later.
When Enid shows Seymour the second half of her sketchbook, and calls him her hero... awwww.
A more bittersweet yet still heartwarming moment just after, when Enid and Rebecca hold hands on the bench.
Hollywood Homely: Enid in the comic is meant to be unappealing, but she's drawn in such a Moe way that it's hard to believe. And in the film, even though Thora Birch gained twenty pounds for the role, Enid is still quite cute, despite the thick glasses and unflattering clothes and hair she wears.
Unintentional Period Piece: The depiction of racial sensitivity is clearly a product of the pre-Obama era, as the issue of racism is treated like a Pandora's Box rather than something to directly confront and address.
The Woobie: Seymour's had it pretty rough. He does have an aggressive side, however, which sometimes leads to trouble.