Chet: Pussy! Pussy! Pussy! Come on in, pussy lovers! Here at the Titty Twister, we're slashing pussy in half! Give us an offer on our vast selection of pussy! This is a pussy blowout! Alright, we got white pussy, black pussy, Spanish pussy, yellow pussy! We got hot pussy, cold pussy! We got wet pussy, we got... smelly pussy! We got hairy pussy, bloody pussy! We got snapping pussy, we got silk pussy, velvet pussy, naugahyde pussy, even got horse pussy! Dog pussy! Chicken pussy! Come on, you want pussy? Come on in, pussy lovers! If we don't got it, you don't want it! Come on in, pussy lovers!
After Kate's had an encounter with a vicious (and legless) vampire, one of the other survivors acts very gentlemanly towards her, most likely to keep her calm. Then we get this.
Kate: What's your name?
Sex Machine: Sex Machine, nice to meet you.
Sex Machine trying to hide that he's turning into a vampire.
Sex Machine: (Listening to Frost's war story when the sound is suddenly drowned out and replaced by a raspy voice)
Voice: Kill them....KILL THEM!
(Sex Machine rubs his ear trying to figure out what's going on, then notes he suddenly has fangs in his mouth. He covers it with his hand... only for it to turn into a claw. When he looks it over his other hand turns into one as well. When Scott look at him he quickly hands it behind his back and tries to act as if nothing's wrong.)
Even better is the fact that it's a Brick Joke to an earlier scene where Carlos tells his recent victim the different flavors of a soul and that they're like a variety pack of popsicles.
When Katie introduces Sex Machine she tells everyone he hit on her. Both Jacob and Seth point their guns at him simultaneously.
The rescue of Kate from the altar early in the temple, just after Frost allowed a weapons-restock from the Shopping Spree wheel-of-forktune, everything from Sex Machine's dual flashlit katana lightsaber (all of the heavily improvised weapons they sling) to the response to a pack of culebras coming in from every doorway while Seth, Jacob and Sex Machine huddle around Kate.
Sex Machine: It's chingon-stop action!
When Sex Machine's groin gun runs out of ammo:
Sex Machine: Agh! Shot my load!
This little moment from the pilot:
Seth:*calling out to Freddie* Now, my brother and I have got what you might want to call a "well-coordinated evacuation" on the way, so I don't want anybody else to die -
After the two hostages break free (and kick the ever-loving shit out of Richie), one of them turns to face Seth and says "There is something really wrong with your brother" before they turn and stalk out of the store.
The trio of Sex Machine, Burt and Scott is absolutely hilarious (and badass) at the same time, what with Scott having to play Straight Man to Burt and Sex Machine, who are constantly at each other's throats - sometimes literally.
Any time Seth and Kisa end up in Snark-to-Snark Combat is great but especially some of their moments in the season two finale.
Kisa: It's all about stealing with you.
Seth: What can I say? I'm consistent.
And later in the episode there's this:
Kisa: You know I could just bite you and make you my slave?
Seth: No thanks. Already had a wife.
After Kisa brings him back from the dead, Carlos provides exposition on where Venganza is, including the fact that the prison she uses as a safe house is rather anarchic. Leading to the Incredibly Lame Pun:
Carlos: I guess you could say... she runs it like a snake pit.
In "Rio Sangre", Kisa's injured pretty badly during a fight and Seth lets her feed off of him to heal herself, after two-plus seasons of not letting anyone feed from him. He walks into Venganza's office, still bleeding from the bite mark on his arm and Richie looks absolutely offended for a minute.
Seth: What? She needed to feed. Richie: ...Smart. You know, I haven't healed yet. Seth: Not a chance.