Billing Displacement: The Gecko Brothers (George Clooney and Quentin Tarantino) are the main characters, yet Harvey Keitel (Jacob Fuller) gets top billing. Though, it could be the fact that this is Clooney's first major starring role, and Keitel was the bigger star at the time.
The Danza: Kelly Preston plays the newscaster Kelly Houge.
Deleted Scene: A scene was filmed featuring a make-up effect where one of the stripper vampires has her stomach open into a large mouth - before shoving a victim's head into it and getting bitten off. The effect was so graphic that even Tarantino didn't want to see it.
Dueling Dubs: From Dusk Till Dawn has been dubbed into Brazilian Portuguese five times, with two versions being recorded at the same studio (Sigma) almost 20 years apart.
Harpo Does Something Funny: The first scene where the vampires reveal themselves and a massive battle ensues was simply marked in the script as "All Hell breaks loose". Also, Salma Hayek's dance as Satanico Pandemonium had no choreographer. Robert Rodriguez just brought her in and let the music move her as it would.
George Clooney was famous for playing a doctor in ER before being cast in this role as a murdering thief. Almost an example of Playing with Character Type, as Seth does have more of conscience than a lot of criminal characters in films like a lot of Clooney's hero characters, but he has rarely played a character before or since that could be described as immoral.
Tough Brooklyn-born Jew Harvey Keitel is a soft-spoken Southern preacher... and a vampire.
The "Ezekiel" speech from Pulp Fiction was originally supposed to be Jacob preparing his stand against the vampires.
Quentin Tarantino was originally set to direct the movie, but decided not to, so that he could focus more on the screenplay and his role as Richard Gecko. Renny Harlin and Tony Scott both expressed interest in directing.
In addition, Roth and Buscemi were approached to play Pete Bottoms, but neither could fit it into their schedules.
The characters of Sex Machine and Frost were originally written the other way around: Sex Machine was to be the muscular, scarred, leather-wearing biker while Frost was to be a more slender (yet deadly) individual.
In the screenplay, Frost was supposed to face off Razor Charlie with the pool cue and Sex Machine was supposed to hurl vampires onto the legs of a table to kill them. In the finished film, their actions are reversed.
Dawson Casting: Averted with 17-year-old Kate, played by 17-year-old Madison Davenport; played somewhat straight with her younger brother Scott, played by 18-year-old Brandon Soo Hoo.
Recycled: The Series: Retells and expands the events in the movie with an entirely new cast. A peculiar example in that it premiered 18 years after the movie did.
Romance on the Set: D.J. Cotrona (Seth) met and dated Eiza González (Santanico) onset from 2014-2016. Prior to this he'd dated Adrianne Palicki from 2011 to 2013 - amusingly, she plays his wife Vanessa in the show.