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Rogues' Gallery Transplant in this franchise.
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"Who she could be is a nightmare list I don't even want to think about...but probably should. Star is an obvious choice. Moonstone. Minn-Erva. Deathbird. Mystique. All contenders. Though Mystique seems too preoccupied these days to come after me. Deathbird too."
Carol Danvers/Captain Marvel acknowledging her past arch-foes; Captain Marvel vol. 10, issue 32 (Mystique and Deathbird have both gone on to become X-Men villains)

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Comic Books

  • Wilson Fisk, the Kingpin, was introduced as a Spider-Man villain, and although very much still a part of Spidey's Rogues Gallery, you'd be hard-pressed to say that the character is not best known for being a nemesis of Daredevil, taking the place of the Owl (who is a lot harder to take seriously) among his enemies. Since he is more of a Big Bad for street-level superheroes in general, Kingpin unlike most examples on this list never completely lost his connection with Spider-Man, and across all media still opposes him on a semi-regular basis, but it's just that his beef with Daredevil is far more personal. This transition is so well accepted that Stan Lee himself confessed that in retrospect, the Kingpin is much better suited as a Daredevil villain and that was the case legally when the film license rights to Daredevil were out of Marvel's hands with Kingpin officially part of that property.
    • The majority of Kingpin's appearances in Marvel Comics have been in Daredevil titles. He made a grand total of 19 appearances in Spider-Man titles before the start of Frank Miller's run, and it was only with Daredevil that Fisk became a Breakout Villain. Fisk's later appearances in Spider-Man are often patterned on the characterization that Miller gave him in that story.
    • Referenced (but not used directly) in Spider-Man: The Animated Series; Fisk is the Big Bad for much of the show, but in the episode where Daredevil does appear, it's made very clear that for him, It's Personal, while for Spidey, it's more of your standard hero/villain thing. Greg Weisman says they wanted Kingpin to be part of The Spectacular Spiderman's Big Bad Ensemble, but couldn't because Sony only had the rights to Spider-Man characters and Marvel officially classifies him as a Daredevil villain now. (They wound up making Tombstone into an Expy of him, and left a few hints that he might be working for somebody else.)
    • On account of the fact that Spider-Man is more of an all-ages character than Daredevil and far more ubiquitous and popular, i.e. it's easier to greenlight a Spider-Man cartoon than a Daredevil one, Kingpin in multiple media still shows up as a regular part of Spider-Man's Rogues Gallery in diverse animated adaptations and video games. His two major live-action appearances have been in Daredevil properties and both of them target a PG-13 to R crowd. He is Spidey's archenemy in the continuity of the Insomniac's Spider-Man game and Big Bad of it's prequel novel (although he is just the Warmup Boss in the game proper, his defeat leading to an Evil Power Vacuum that starts the main conflict of the game), he's appeared as a Spider-Man Big Bad in Spider-Man: Into the Spider-Verse (where he murders one version of Peter), and he's part of a Big Bad Ensemble in the Ultimate Spider-Man (2000) comics and Spider-Man: The Animated Series, which still acknowledge him as being a more personal foe of Daredevil, though he's mostly seen giving Spider-Man grief. In 616 comics, Kingpin still appears as a regular foe of Spider-Man but hasn't been the Big Bad of a storyline since Back in Black, which involved Spider-Man cutting loose and mocking Kingpin for having no powers and demonstrating how powerful Peter really is, making it hard for later writers to use him in the traditional way before. As such, Kingpin shows up more as The Man Behind the Man and crime broker for other bad guys than a physical threat in his own right. However, perhaps due to his association with the more adult-oriented Daredevil, the Kingpin does not appear in the Ultimate Spider-Man (2012) or Marvel's Spider-Man cartoons, being left out in favor of different crime lord rogues that were solely Spider-Man villains, most notably Hammerhead.
    • He ends up as the final Big Bad in The Punisher MAX (along with Bullseye and Elektra), a 'verse which has no superpowers.
  • Other Spidey villains have been known to torment Daredevil from time to time, and vice-versa; the guys practically live next door to each other, so there's a ton of overlap (the Beetle being certainly the most recurring after Kingpin). Inverted with Mysterio who seems to have not so much transferred to Daredevil's gallery as branched out, via Guardian Devil, a story that saw Mysterio killed off for a time after trying to break Daredevil (copying what happened in Born Again, only this time it got Daredevil's love interest Karen Page killed), becoming an enemy of both of them. Then he ended up switching to Spider-Men. Electro was prominently considered part of both Spider-Man and Daredevil's galleries at the same time during their early years.note  Case in point: The first Amazing Spider-Man annual had various supervillains Spidey had defeated before gang up, as the Sinister Six, in order to have their revenge on him. When Daredevil got an annual, too, we saw Electro forming the Emissaries of Evil consisting of villains who wanted revenge on DD. He later went on to fight a larger variety of heroes before ultimately becoming associated with Spider-Man again, though he is well known for being hired to cause a breakout at the Raft that formed the New Avengers.
  • While primarily an enemy of Spider-Man, Doctor Octopus has had notable clashes with Iron Man, a rival genius. He's also antagonized Captain America, The Incredible Hulk and other New York based character like Daredevil and The Punisher.
  • The various Green Goblins were notable for being solely Spider-Man villains, never antagonizing other New York-based heroes as Doc Ock or Electro would. Since Secret Invasion (2008), however, Norman Osborn has been transformed into an over-riding Big Bad of the Marvel Universe, specifically clashing with the New Avengers. After trying to take the Avengers again with another team of Dark Avengers and a H.A.M.M.E.R. made up of HYDRA and A.I.M. personnel, he has gone back to being a Spidey villain. Firmly reestablished at the Grand Finale of Superior Spider Man. The run of Captain America by Ta-Nehisi Coates would then include him in the Power Elite that opposed Captain America.
  • Since his resurrection Kraven the Hunter and his daughter Ana have been seen fighting other superheroes on a daily basis, mostly related to Spider-Man like Venom, Spider-Girl or Scarlet Spider, but Black Panther and the Hulk are also fair game. It helps Kraven seems to now live in the Savage Land, a place commonly visited by various superheroes.
  • In Anya Corazón's time as Spider-Girl, most of her antagonists were minor Spider-Man villains, like the Ana Kravinoff, Screwball or Hobgoblin.
  • During Kaine's tenure as the Scarlet Spider, he seems to have inherited the Jackal, the Lobo siblings, Shathra, Kraven and Ana Kravinoff from his 'brother', Spidey (though the Jackal is his creator and therefore a long standing part of his story), the Hand from Daredevil, Belladonna Boudreaux and the Assassins Guild from Gambit, Carnage from Spider-Man/Venom and evil MegaCorp Roxxon from Iron Man — though for Roxxon, it's shared custody with Thor (and more recently the Hulk). Now, he's (reluctantly) one of the New Warriors and as a result seems to have acquired the High Evolutionary and the Evolutionaries from the X-Men.
  • Speaking of, the High Evolutionary originated in the pages of The Mighty Thor, but has since gone on to encounter the Avengers, the Fantastic Four, Adam Warlock, the Silver Surfer, the X-Men, the Guardians of the Galaxy, the Heroes for Hire, the Uncanny Avengers and even the New Warriors. What makes him somewhat unique is that he is often an ally rather than an enemy, depending on who is writing at the time. He notably appeared as the main antagonist of the Evolutionary War Crisis Crossover during the 80s, where his machinations threatened pretty much the entire Marvel Universe (including an appearance in Marvel's ALF comic, of all places, which later become semi-canon). He also played a role in the origins of Scarlet Witch, Quicksilver and Spider-Woman.
  • The Iron Man storyline Armor Wars has Tony go after a few non-Iron Man villains like the Beetle (originally an enemy of the Human Torch and later, Spider-Man) and the Gremlin (a Hulk villlain).
    • Doctor Doom is one of the villains Tony suspects might have used his stolen technology. Averted in this case as it's not true.
    • Zig-Zagging Trope with Gremlin. Gremlin uses the name and the armor of the Titanium Man, an Iron Man foe who goes way back, but Gremlin himself is primarily a Hulk villain, first appearing in The Incredible Hulk #163.
    • Stilt-Man, appearing in Iron Man #225, is a straighter example, starting out as a Daredevil villain (his first appearance in Daredevil #8), and having fought Spider-Man before this.
  • The Phoenix Force, while going back and forth through the Heel–Face Revolving Door at a rate of knots and often subject to Blue-and-Orange Morality, is usually near inextricably related to the X-Men and their associated books, such as Excalibur - and in the latter case, only because Rachel Summers was on the roster. Recently, however, the entity first became a global threat in Avengers vs. X-Men, then shuffled over to the Thor books under Jason Aaron's pen, making an important appearance in Thor (2014) and the King Thor sections of his Thor run, being revealed to have a complicated relationship with Asgard (having hooked up with both Odin and Thor in the past). While she simultaneously appeared in the Jean Grey book in the run up to Phoenix Resurrection, the culmination of that book had Jean firmly tell the entity to sod off and leave her alone, suggesting that she's out of the X-Men's orbit for the time being. The Phoenix Force returned in a big way for a storyline in The Avengers (Jason Aaron), which ended with former Avenger and recurring Daredevil ally Echo becoming the entity’s new host.
  • Given that Nate Grey a.k.a. X-Man dropped in out of alternate universe very early in his history, and wasn't really affiliated with anyone thanks to being a Fish out of Water, a bit of a loner, and deeply paranoid about being manipulated (with good reason). As a result, he had very few villains of his own, at first - Dark Beast, Holocaust, and Sugar Man. And of the three of them, only Holocaust was really stupid enough to pick a fight with him. This plus power plus Chronic Hero Syndrome meant that he ran into everyone's villains at one point or another, including Exodus, the Marauders, the Abomination during his King-of-the-Sewer-People period, Onslaught, Mysterio, Electro, and Stryfe. Heck, he even tangled with Morbius briefly. Also Maddie Pryor, when she wasn't helping him. The main one, though, was Apocalypse who represents everything Nate despises and is the root of his concept of evil.
  • Spidey inherited minor Captain America villain Vermin, J.M. DeMatteis basically pulling a Chris Claremont - though it was a relatively smooth transition, as Spidey first encountered Vermin in a team-up with Cap.
  • Shriek was introduced as an opponent for Cloak and Dagger, but after Maximum Carnage she is more known as a Spider-Man villain and girlfriend of one of his most famous antagonists, Carnage. Speaking of Carnage, Marvel lately seems to be trying to invoke this and move him to fight other characters, like Kaine, Sam Alexander or Deadpool.
  • Swarm was originally created as a Champions villain, but soon became far more associated with Spider-Man.
  • Fin Fang Foom was originally a general Marvel Universe monster. He became an Iron Man villain to the point that he has appeared in both Iron Man: The Animated Series and Iron Man: Armored Adventures cartoon series, was featured in the animated movie, and was considered as a foe for the live-action Iron Man movie... presumably without the purple shorts. He still shows up in a Freeze-Frame Bonus, on a billboard.
  • In her first appearance, Moondragon was an Iron Man villain named "Madame MacEvil." Subsequent appearances would see her take on more of an Anti-Hero role, with her eventually becoming a member of the Avengers, The Defenders and the Guardians of the Galaxy.
  • A minor Iron Man villain named Scarecrow, a former acrobat, never battled him after his first appearance; he bounced around quite a bit, battling the X-Men, Captain America and The Falcon, before becoming an enemy of Ghost Rider for quite a while; nowadays he's just puttering around.
  • Black Knight (Nathan Garrett) was originally an enemy of Ant-Man and The Wasp, but was a founding member of the Masters of Evil, the first supervillain team foes for The Avengers, and then ended up better known as an enemy of Iron Man before being replaced by his heroic nephew. It got to the point where in Iron Man: Armored Adventures, he's depicted exclusively as an Iron Man villain.
  • Speaking of Black Knight, Dreadknight was later introduced in the pages of Iron Man as something of a replacement Expy, being a knight-themed supervillain with a high-tech lance, a similar costume and even the same flying horse. However, these same qualities have also led him to battle Dane Whitman, the heroic Black Knight (and Garrett's Redeeming Replacement), with Dreadknight effectively serving as Dane's Evil Counterpart.
  • Mephisto works well as a deliberate example: He was originally introduced in the Silver Surfer series, but has spent stints as an adversary of both The Mighty Thor and Ghost Rider. To the modern reader, though, he's best known for his role in One More Day, a Spider-Man story. Mephisto is best understood as a member of the Rogues Gallery for the wider Marvel Universe, rather than any one hero, which is fitting as he is basically a stand-in for Satan. He has tangled with nearly every single major hero and several villains, and is a lot more personal for many. He was notably the Big Bad of The Avengers (Jason Aaron), where it was revealed that there's even a Council of Red made up of Mephistos from across the multiverse.
  • Crossfire first appeared as an enemy of Moon Knight in an issue of Marvel Two-in-One, with the two even having a shared past from their time as CIA agents. However, he's since become more associated with Hawkeye and the Scott Lang version of Ant-Man, particularly since his brother, Darren Cross, was the latter's Starter Villain.
  • Rhino was introduced as a Spider-Man foe but has spent a large chunk of his career battling the Hulk due to him being one of the physically strongest Spider-Man villains. At the very least, it's shared custody.
  • Thanos first appeared as an enemy of Iron Man. This is because Thanos's creator, Jim Starlin, was offered to write an issue of Iron Man's comic and created Thanos to be the villain for that issue. When Starlin began writing Captain Marvel he reintroduced Thanos and the rest is history. Thanos is now linked with the Silver Surfer mythos, (Marvel Comics') Captain Marvel, and Adam Warlock. As of 2021, he’s also become a major villain for his extended family, the Eternals. Like Mephisto, he's now pretty much a general enemy of the entire lineup of "Cosmic Marvel" characters, if not the whole Marvelverse. Interestingly enough, the Marvel Cinematic Universe reverses this with Thanos being shown in some later films to have started off already a major threat in space (at least personally to his adoptive daughters Gamora and Nebula), but his onscreen debut is The Avengers (2012), where he masterminds the plot and eventually becomes the main threat of the Avengers, and the Arch-Enemy and Evil Counterpart of Iron Man, ironically the very character he originally faced.
  • Wolverine started out as a foe of the Hulk before becoming primarily associated with the X-Men.
  • Nebula was conceived as the nemesis of the second Captain Marvel(Monica Rambeau), but remained a general Avengers villain after Captain Marvel mostly disappeared from the book and focused more personally on Starfox. Then she became a frequent opponent of The Silver Surfer before appearing in Loki's stories when he was trying to reform. Then she joined Gamora's team Graces only to betray Gamora and turn the group against her. Then Nebula became a general Guardians Of The Galaxy enemy.
  • The Celestials originated in Jack Kirby's The Eternals, but have since crossed paths with Thor, the Fantastic Four, The Avengers, and even the X-Men.
  • Sabretooth was a foe of Iron Fist. Incidentally, Sabretooth was originally intended to be Wolverine's father by creator John Byrne (he was based on Byrne's rejected design for Wolverine sans mask), but ended up getting dumped onto the Iron Fist title when Claremont and Cockrum weren't interested. Years later, Claremont decided to bring Sabretooth into the Wolverine fold; though he has yet to be confirmed as his father, he still is his Arch-Enemy.
  • Lady Deathstrike first appeared as a supporting character in a Daredevil storyline before becoming integral to Wolverine's story.
  • The first Silver Samurai, another character closely associated with Wolverine and the X-Men, also first appeared fighting Daredevil. And while he's best known as a Wolverine villain now, he's also clashed with Shang-Chi, Black Widow and Spider-Man. His son, Shin Harada, originated as a Wolverine villain, but also battled Jane Foster during her time as the new Thor.
  • Nuke first appeared as an enemy of Daredevil in the iconic Born Again storyline, but his ties to Project Rebirth (and, by extension, Weapon X), as well as his general concept of being a crazed Super-Soldier, made him a perfect fit for the likes of Captain America and Wolverine.
  • The Collector first showed up as an Avengers villain, but thanks to his habit of stealing rare artifacts and organisms, he's clashed with the likes of the Silver Surfer, Wolverine, the Hulk, and Star-Lord. The Contest of Champions (2015) series also had him as a general threat who, alongside the Maestro, kidnapped a number of Marvel characters from across the Multiverse to force them to fight to the death.
  • Lucifer started off as a very minor X-Men villain before eventually battling characters like Iron Man and The Falcon. His successor, Dominus, would later fight the West Coast Avengers.
  • Ultimate Spider-Man (2000):
  • A temporary case - today, the Sandman is best-known as a Spider-Man villain, and he indeed made his first few appearances in The Amazing Spider-Man, but during the '60s and '70s he mostly pestered the Fantastic Four, either solo or as part of the Frightful Four. In fact, the very first issue of Marvel Team-Up (a 1972 Christmas special) has Spidey claiming he only fought Sandman once, and the FF are the real "Sandman experts".
  • The contract killer Boomerang, who uses deadly gimmick boomerangs as his weapons, originally started out fighting the Hulk, before he moved on to become a semi-regular Spider-Man villain after writers realized that trick boomerangs versus the most powerful creature on Earth was a bit of a mismatch. Boomerang even appears in the Uncanny X-Men Nintendo game by LJN even though he's neither a X-Men enemy nor a mutant.
  • Mister Hyde, a villain based on The Strange Case of Dr. Jekyll and Mr. Hyde, started out as a Thor villain but would later move on to become a Daredevil regular, although he also took the time to mess with Spider-Man, Captain America, Ghost Rider, and the Hulk, finally settling in to become a regular foe of Cap, DD and the Big Green Machine. These days he seems to have moved to fighting teen heroes, considering his appearances in both Young Avengers and All-New Ghost Rider. He was later revealed as the father of Daisy Johnson, and has been a foe of her as well.
  • Cobra, Mister Hyde's sometime partner, also started out as a Thor villain. He quickly figured out that his 'powers' of being double-jointed and crawling on his belly didn't make him capable of challenging the god of thunder and became a foe of Daredevil and Captain America.
  • In the very early days of the Silver Age Marvel Universe, the Fantastic Four's Human Torch had his own rogues gallery as a solo hero. Two of his mainstays, the Wizard and the Trapster, would later become enemies of the Fantastic Four, with the Wizard becoming an Evil Counterpart to Reed Richards and even forming his own Evil Counterpart team in the Frightful Four, of which the Trapster was a charter member. The Trapster and the Beetle, another long-standing enemy of the Torch, would also become recurring enemies of Spider-Man. It's so pronounced that in both the Ultimate Spider-Man comic and TV show, the Beetle is more or less treated as a straight-up Spidey villain (being a founding member of the Sinister Six there). Though during the days he wore his first costume, he fought Daredevil more often, only to completely abandon him with his upgrade, choosing Iron Man as a secondary nemesis. The Eel also originally debuted as a foe of the Human Torch before becoming a semi-regular Daredevil villain.
  • Current Beetle debuted as a one-time enemy of Captain America, but is now better known for her role in The Superior Foes of Spider-Man. Of course, Spider-Man was The Ghost in that series, and writer Nick Spencer wrote her into a Dating Catwoman scenario with Scott Lang during his later run on Ant-Man, so she probably rates more highly in Scott's Rogues Gallery at this point. She was fully shunted into Spider-Man's gallery come The Amazing Spider-Man (2018).
  • Many of the enemies the various members of The Avengers had faced as solo heroes would later become enemies of the team as a whole, with characters like Egghead, an enemy of Ant-Man, a.k.a. Henry Pym; Baron Zemo, (an enemy of Captain America and the founder of the original Masters of Evil); Loki, an enemy of The Mighty Thor (unique in that he also was their Starter Villain); and the Mandarin, the Arch-Enemy of Iron Man, all becoming some of the Avengers' worst enemies. This would also get inverted. The first incarnation of the Masters of Evil featured the Black Knight as a foil for Wasp and Giant Man and Radioactive Man as the foil for Thor. Soon after, both became regular enemies of Iron Man.
  • Speaking of Baron Zemo, though he's best known as an enemy of the original Captain America, he's also menaced Steve's successors to the mantle, Bucky Barnes and Sam Wilson. Zemo's connections to the Thunderbolts have also given him a grudge against Hawkeye, leading to appearances as a major antagonist in both Hawkeye: Blind Spot and Old Man Hawkeye. Lastly, he clashed with The Punisher during the latter's brief stint as the new War Machine, and subsequently appeared as one of the main villains of the ensuing 2018 Punisher relaunch.
  • The Multiversal Masters of Evil from The Avengers (Jason Aaron) are an interesting variation on the trope. The group is comprised of Doom Supreme, Kid Thanos, Ghost Goblin (Green Goblin as a Spirit of Vengeance), King Killmonger (Erik Killmonger inside the Asgardian Destroyer armor), and Dark Phoenix (Mystique as a Phoenix Force host), all of whom do traditionally have some connection to the Avengers or at least one of their individual members. However, with the exception of Kid Thanos (who is simply a child version of Earth-616's Thanos), the Masters are all Variants from alternate realities, and thus have no real history with the Avengers of Earth-616.
  • Graviton is primarily an Avengers villain, but was also a major recurring adversary of the original Thunderbolts. He's also faced other heroes like Shuri and Miles Morales.
  • Michael Korvac was first introduced as a one time enemy of The Defenders, but later became best known as the main antagonist of The Korvac Saga in The Avengers.
  • The Enchantress is normally an enemy of Thor and/or The Avengers (she's been known to tangle with the Scarlet Witch on occasion), but she has branched out - at one point she became the arch-enemy of Dazzler, of all people; recent events have had her teaming up with the new Lady Deathstrike and Typhoid Mary to counter the X-Men (Mary herself is normally an enemy of Daredevil)
  • Mystique first appeared in Ms. Marvel and was originally slated to be her Arch-Enemy. She's pretty much entirely an X-Villain nowadays, and her history with Ms. Marvel (such as killing her boyfriend) has been all but forgotten. She did return to torment Ms. Marvel in Carol's later series.
    • As far as individual X-Men, She tends to have the most conflict with Rogue (her adopted daughter), Nightcrawler (her biological son), and Wolverine (her former lover).
  • The Sons of the Serpent originated in Stan Lee's run on The Avengers, but later had memorable battles with Daredevil and The Defenders. Their status as a white supremacist organization dedicated to ridding America of minorities has also led to run-ins with the likes of Sam Wilson, Monica Rambeau and the Young Avengers.
  • This goes for a lot of the evil organizations of the Marvel Universe like HYDRA (originally enemies of Nick Fury and S.H.I.E.L.D.), A.I.M. (originally enemies of Captain America) and the Hand (originally enemies of Daredevil), all of whom have fought various solo superheroes and teams as general threats to the Marvel Universe.
  • Apocalypse first appeared in X-Factor as the leader of the Alliance of Evil (a role, again, originally intended for the Owl) eventually becoming their Big Bad, getting killed, and, upon resurrection, graduating to become one of the X-Men's most powerful foes and being retconned as Cable's archenemy. The former might not be quite enough to qualify as this trope since the incarnation of X-Factor that had Apocalypse as the Big Bad consisted of the original five X-Men, making the whole thing X-Men in all but name to begin with. Cable, on the other hand, while very much an X-Men related character, especially due to him being the future son of Cyclops and Jean Grey, has his own distinct rogues gallery that usually only overlaps with the X-Men during crossover events. Since Jason Aaron took over the Thor title and the beginning of Uncanny Avengers (where he and Thor were manipulated into a confrontation by Kang), he also became a part time enemy of Thor - albeit usually in flashbacks when fighting a pre-Mjolnir Thor, who holds something of a grudge against him for a beating that Apocalypse handed out to him. Since Apocalypse has been worshipped as a god, and is a Physical God in terms of raw power anyway, it's fitting.
  • Deathbird started as a Ms. Marvel villain before becoming a recurring foe of the X-Men in general and Professor X's girlfriend Lilandra (her sister, as it turns out) in particular. Like Mystique above, this is a result of Chris Claremont creating a villain for one book, then moving her to another when the first was canceled.
  • The Brood are another Claremont example, having first been introduced as enemies of the X-Men before going on to fight other characters like Carol Danvers, the Avengers and the Guardians of the Galaxy.
  • In his initial few appearances, Kang the Conqueror was a Fantastic Four villain called Rama-Tut, with it even being implied that he was a future descendent of Doctor Doom. After taking on his far better known name and appearance as Kang, he primarily battled the Avengers, though he still shows up to menace the FF and other heroes from time to time.
  • The first Moonstone was a Captain America villain, and the woman who would eventually steal his powers as the second Moonstone was initially an Evil Minion who was of little concern to Captain America. When she became a full fledge super villain she started off as a foe of the Hulk, but became more of a general Avengers villain after joining the Masters of Evil, forming a direct rivalry with the second Captain Marvel(Monica Rambeau). Then she became a rival to Baron Zemo and the third Captain Marvel/second Photon, Genis-Vell, during Thunderbolts. Then during Dark Reign, she was positioned as Ms. Marvel's Evil Counterpart in Norman Osborn's Dark Avengers. She continues to oppose Carol Danvers as she becomes Captain Marvel #6, though not always willingly.
  • June Covington, aka "Toxic Doxie", started off as one of Norman Osborn's allies from his limited series. She went on to menace the New Avengers as the Dark Avengers' impostor Scarlet Witch, but has since settled on terrorizing Captain Marvel. This is because June was originally created by Kelly Sue Deconnick, who then brought the character over to the Captain Marvel book once she started writing it.
  • Blackout was originally an obscure Nova villain, but is probably best remembered for his role in Roger Stern's The Avengers run, where he battled the team as part of the Masters of Evil. On a more specific level, his powers were used to counteract those of Captain Marvel #2(Monica Rambeau).
  • Arcade debuted in the pages of Marvel Team-Up, a title that had Spider-Man teaming up with other Marvel heroes, but these days is better known as an X-Men villain. He did resurface in The New '20s in The Amazing Spider-Man (2018) as part of the Hunted arc before jumping back to the X-Men in Hellions.
    Young!Cyclops: Uh, what're you guys doing here?
    Deadpool: Hi-ya, Mini-Cyclops! We got a present for you!
    Spider-Man: We know he's not a mutant, but even though I fought him first he's somehow become part of the whole X-Men deal. Which makes him your deal.
    • Arcade was the main villain for young Marvel superheroes for a time, trapping the Avengers Academy kids and the Modern Age Young Allies in Murderworld, and doing the same in Avengers Arena with more teen superheroes.
  • The demon Blackheart debuted in Daredevil, though now spends most of his time messing with Ghost Rider, even appearing as the villain in the movie adaptation. He also shows up in X-Men from time to time (amongst others), even at one point serving as the Black King of the Hellfire Club. He’s also had run-ins with Miles Morales and The Falcon.
  • The Marvel version of Ball-Hadad was originally a Wolverine, but has since become more associated with Ghost Rider.
  • The death angel Lazaer, whom frequently poses as the more famous Azrael/Azriel, was originally an enemy to the Marvel Comics version of Venus, but has since become more associated with Wolverine.
  • Ghost Rider villain Night Terror eventually became a Blade antagonist. Although it did not last too long, since he really only lasted in the first place because none of Ghost Rider attempts to kill him stuck, but Blade was actually equipped end him for good.
  • The Purple Man originated as a Daredevil villain, but has since become the Arch-Enemy of Jessica Jones.
  • Minor-league Iron Man villains Blizzard and Firebrand started out fighting Shellhead, but eventually transitioned to fighting street-level heroes like Spider-Man after Tony Stark's equipment began to completely outclass theirs. And Shellhead's greatest foe, The Mandarin, took time out - primarily in the 60s and 70s - to deal with other characters. The very first Avengers annual had Enchantress and Executioner, Living Laser, the original Power Man and the Swordsman working for him to distract the Avengers from his plan of broadcasting worldwide hate-rays. The late 60s had him clash with the Hulk a few times (one time getting Nick Fury involved, another involving the Sandman, normally a Spider-Man foe), another time he kidnapped a peacemaker who was rescued by Captain America, and still another time saw him encounter the Inhumans in an attempt to gain a Makluan artifact. Since then though, he's been sticking with Iron Man.
  • Living Laser originally appeared as a foe of The Avengers, fixated on The Wasp, before later becoming an enemy of Iron Man.
  • Moses Magnum started out fighting Spider-Man and The Punisher, but seems to have eventually settled on antagonizing Black Panther. Thematically, Magnum and T'Challa are a perfect fit, and Iron Man: Armored Adventures chose to have Magnum murder T'Chaka instead of Klaw.
  • Klaw is a Black Panther villain, but he's also a fairly prominent enemy of the Fantastic Four (debuting in their comic, where Black Panther also debuted), and has menaced Daredevil a number of times as well. Generally, Klaw can be counted on to antagonize anyone associated with his original foes, the FF and Black Panther through Revenge by Proxy. He's menaced the Avengers a few times, even if Black Panther isn't in the line up and will go after the next available hero if his original target isn't around. After his first defeat and transformation into living energy, his first act is to travel to New York and get revenge on the FF for helping Black Panther.
  • The Absorbing Man, who was able to mimic and absorb the physical properties of anything he touched, started out as a recurring enemy of The Mighty Thor and remains a charter member of Thor's Rogues Gallery. However, he's also tangled with the Hulk enough times that it's arguably shared custody.
  • Doctor Doom was created to be the main nemesis of the Fantastic Four. While he still maintains that role to the present day, he has since become one of the overall Big Bads of the Marvel Universe and has fought pretty much every single Marvel hero. Most prevalent are his tussles with Black Panther, which makes sense because Panther was originally introduced as a Fantastic Four ally and a Good Counterpart to Doom in the first place. Doom is also known for his roles in classic Iron Man stories and the graphic novel Triumph & Torment where he meets Doctor Strange. Even other villains are not safe from Doom. He will gladly co-op with the heroes if he feels it serves his interests (of course, once the interests are served...) This is so pronounced that it's even reflected in marketing. For instance, Hasbro's "Titan Hero" action figure line usually references the installment each hero or villain comes from (Iron Man 3, Avengers Assemble, Thor: The Dark World, Guardians of the Galaxy (2014), etc.), but the packaging for the Doctor Doom figure contains no indication that he belongs to the Fantastic Four franchise. One of the most famous storylines with him as the Big Bad was Avengers: The Children's Crusade. It involved many named characters such as the Young Avengers, The Avengers, X-Men, and even X-Factor — yet the first family themselves were no shows.
  • M.O.D.O.K. was originally created as a foe for Captain America. However, in his role as leader of AIM, he's increasingly become an antagonist of Iron Man. And then the Hulk, as he created Red Hulk.
  • Annihilation has the Fantastic Four's long-time foe Annihilus launching a devastating attack on the universe, uniting cosmic heroes like Nova and the Silver Surfer against him. Even through Annihilus returned a few years later to fight the first family again, he is now generally considered a threat to the entire universe.
  • Annihilation: Conquest does a similar thing - Avengers villain (created by Ant-Man) Ultron takes control over the Phalanx, a race mostly known for their fights with the X-Men, as well as a few lesser-known villains like the Avengers' enemy Super-Adaptoid or the Fantastic Four's foe Blastaar, and then goes against cosmic heroes. Ultron later returned to fighting the Avengers, though.
  • In a similar vein, War of Kings is driven by conflict between the Kree Empire, ruled by The Inhumans, and the Shi'Ar Empire, ruled by X-Men foe Vulcan. Time will show which group Vulcan will stick to antagonizing.
  • The Super-Adaptoid was introduced as an enemy of Captain America, but very quickly moved on to fighting the X-Men and Avengers as well (fittingly, as it originally possessed the combined powers of the latter team at the time). Nowadays it's mostly considered an Avengers villain, though that hasn't stopped it from also mixing it up with the likes of Spider-Man and the Hulk on occasion.
  • While Namor's Silver Age return pegged him as a Fantastic Four villain and Mister Fantastic's romantic rival, Stan Lee and Jack Kirby quickly established him as a threat to the wider Marvel Universe by having him also fight the Avengers and X-Men. His constant Heel–Face Revolving Door tendencies have led him to clash with a great many Marvel heroes over the years, including Black Panther and the Squadron Supreme.
  • The Super-Skrull originated as a Fantastic Four foe (even having the combined abilities of all four members of the team), but quickly became a general cosmic villain (and sometimes Anti-Villain), fighting Kree-based heroes like Mar-Vell and Carol Danvers and showing up in Silver Surfer's book during the 90s. He's also faced off against other Earth heroes like Thor, the Hulk, the Avengers, Doctor Strange, Namor and even Tigra on occasion.
  • This applies to the Skrulls as a whole. They began as enemies of the Fantastic Four, but gradually became a threat to the entire Marvel Universe, which was cemented by Secret Invasion. Ditto for the Kree, the archenemies of the Skrulls.
  • Shuma-Gorath was actually first mentioned in a Robert E. Howard short story, but has been better known for his classic fights against Doctor Strange. He more or less lost his association with the good doctor when he unexpectedly appeared in Marvel Super Heroes, where Strange was absent. Due to the Howard connection, Shuma also menaced Conan the Barbarian in his Marvel series, as well as the Savage Avengers when Conan was part of that group. The Thanos Imperative and a few other appearances helped him get upgraded to universal threat, like Mephisto or Thanos, and he later served as a Starter Villain for Luke Cage's incarnation of the Mighty Avengers (2013). Similarly, Nightmare started as a Doctor Strange foe, but has since then fought with pretty much everybody.
  • Juggernaut was and still is one of the X-Men's most iconic and recurring adversaries, but quite possibly the most famous comic book story he had ever been in was Nothing Can Stop the Juggernaut!, where he tangled with Spider-Man. The story was meant to establish Spidey as the ultimate underdog, where the Juggernaut, a character Spidey normally never has to deal with and far outside his weight class, is causing trouble and Spider-Man is the only one there who can stop him. This battle got a modern sequel in the The Gauntlet arc.
    • Juggernaut also has a long-standing rivalry with the Hulk, as the irresistible force to Hulk’s immovable object, and has clashed with him many times over the years.
  • Demogorge the God Eater and Amatsu Mikaboshi both debuted as antagonists of The Mighty Thor. To modern readers they are probably known as enemies and occasional allies of The Incredible Hercules.
  • The Punisher has few reoccurring villains due to his deadly nature but one of his few villains, Jigsaw, started off as a Spider-Man villain, although his introductory story did involve Punisher as well. Punisher himself was a Spider-Man villain; however he was more of an antagonistic Anti-Hero and now has his own titles where he scuffles with every street level hero when he's not massacring normal criminals.
  • Jimmy Natale's Vulture started off as a Spider-Man villain before moving over to the Punisher's corner of the Marvel U during Greg Rucka's run. He didn't survive the trip.
  • The crossover event Acts of Vengeance best describes this trope. It involves the very idea of a wide array of super-villains facing heroes they had never met (or at least were villains that weren't part of the heroes' regular gallery). Such examples were Alpha Flight fighting Scorpion, Spider-Man (who was granted cosmic powers at the time) fought Goliath, The Brothers Grimm, Titania, Magneto, Graviton, Trapster, Dragon-Man, and the Tri-Sentinel. Daredevil fought Ultron, Thor fought Juggernaut, Mandarin appears in the X-Men issues, and Rusty and Skids of the New Mutants battle the Vulture. Even Magneto went against the Red Skull for very obvious reasons (Magneto (a Holocaust survivor) barely tolerated the Red Skull as a co-conspirator under the impression that he was a modern villain using the Skull's mask and image to frighten people. When he realized the Skull was the actual protege of Hitler and WWII war criminal . . . he buried the Skull in a light-less fallout shelter with a dozen jugs of water and sealed it shut.) Similarly the event Infinity Warps does the same thing, being an homage to Acts of Vengeance. Across the merged universe it takes place in, superheroes find themselves under attack by other people's enemies.
  • Grey Gargoyle was always a Thor foe. However, he's faced Captain America and Falcon a few times and got on Nick Fury's attention when he hired himself out to AIM. He's basically faced most of the major Marvel heroes following Acts of Vengeance: Hulk, She-Hulk, Spider-Man, Iron Man, and the Fantastic Four. It probably helped that he appeared on the cover of an Iron Man comic in the '90s that led to him being cast in Iron Man: The Animated Series as one of Mandarin's henchmen. In the 2024 Cable series, he's gone off and is in the way of the time-travelling X-Men soldier.
  • Baron von Strucker was introduced as Nick Fury's Arch-Enemy, but, as the leader of HYDRA, he's also clashed with the likes of Daredevil, Captain America, the Avengers, Wolverine, Black Panther and the Thunderbolts. A memorable issue from Chris Claremont’s X-Men run also revealed that Strucker played a key role in the shared backstory of Professor X and Magneto, having fought against both mutants back when they were young men in the years after World War 2.
  • Marv Wolfman originally created Black Cat as an enemy for Spider-Woman; however, Wolfman was transferred to Spider-Man before he could introduce her, and he brought her with him.
  • Thanks to sharing continuity, Marvel's G.I. Joe series had an entire story arc with Megatron as the antagonist.
  • An inversion happened to The Pride - they were always antagonists of the Runaways and it would be pretty hard to introduce them fighting any other superheroes while their entire point was they kept their operations under their radar. That was the case until the creation of Avengers Illuminati who were also working in secret from the entire Marvel superheroic community. So of course there exist comics that revealed the two groups clashed back in the days when the Runaways were still only kids.
  • After Doctor Sun was defeated in The Tomb of Dracula by the joined forces of Dracula and the vampire hunters, he went to antagonize Nova and the Fantastic Four.
  • Dracula himself also qualifies, though he didn't start out as anyone's rogue and happened to fight any superhero who crossed his way like Thor, Silver Surfer or Dr. Strange. With that said, he went on to became a recurring antagonist to Blade (who, ironically, starred in Dracula's own series and became hugely popular afterwards) and regularly clashed with the X-Men-related characters more than with any other hero, such as Storm (leading to one alternate reality where Storm was a vampire), Old Man Logan and Deadpool. It was revealed that even X-Men's Big Bad Apocalypse was Dracula's Arch-Enemy at one point.
  • Mad Scientist Dr. Bong began life as the foe of Howard the Duck, but recently he seems to have largely migrated over to being part of Deadpool's supporting cast (probably because of Howard not having a regular title for years). Deadpool has also tangled with Bullseye enough as a Friendly Enemy that it's practically shared custody.
  • The Crime Master and Jack O' Lantern were traditionally Spider-Man villains, but after Agent Venom/Flash Thompson got his own book they made the jump with him and settled down as his archenemies.
  • Cobalt Man was originally a very minor Silver Age X-Men villain, but soon drifted away from that corner of the Marvel Universe and instead fought characters like the Hulk and The Defenders.
  • Black Tarantula debuted as a Spider-Man villain, but most of the modern readers are probably more familiar with him undergoing a Heel–Face Turn and becoming a supporting character for Daredevil, or with his son taking the name and antagonising Spider-Girl in her universe.
  • This is actually part of the Marvel creative process - villains are catalogued by the hero they fight with and if you have to use any, you need to ask the editor overseeing that character at the moment. But if you write a very good story with the villain or use him a lot, he might be moved. For example, when Uncanny Avengers was heavily using the Red Skull, writers had to ask that book's editor for permission to use him, instead of the Captain America editor.
  • Samuel Saxon started out as a Daredevil villain, both under his nickname "Starr" Saxon as well as the second Mister Fear. However, after being killed off in a Daredevil issue and receiving an Emergency Transformation, he's pretty much exclusively been a Captain America villain as the android Machinesmith.
  • While Magneto is primarily known for his complicated relationship with the X-Men, he has tangled with all of Marvel's major heroes as well, particularly the Avengers, Fantastic Four, Thor, and Spider-Man. A key moment in his backstory, where he was deaged to infancy, actually occurred after a fight against The Defenders.
  • With Peter Parker becoming head of Parker Industries during the All-New, All-Different Marvel event and Spider-Man dealing with bigger foes, his previous street-level Rogues Gallery is now being handled by Miles Morales, Spider-Woman, and Silk. Both Silk and Miles have dealt with Black Cat, and Spider-Woman has gone up against Hobgoblin.
  • Speaking of Spider-Woman, Morgan Le Fay used to be her arch-nemesis, but now she's a general Marvel Universe villain, mainly tangling with the Avengers. This included an encounter with the Dark Avengers, due to her targeting Doctor Doom for revenge. In the 2014 volume, Spider-Woman mainly fought C-list/D-List villains such as Tiger Shark (a traditional Sub-Mariner villain), the Sandman (a Spider-Man villain), and the Blizzard (traditionally an Iron Man villain).
  • Roxxon Energy, the evil energy MegaCorp, are mostly known for pestering Iron Man, but are also enemies of a few different iterations of Deathlok, most notably Michael Collins, who they transformed into a cyborg commando against his will because He Knew Too Much. They later became a recurring problem for Kaine as the Scarlet Spider, and under new CEO Dario Agger (who's also a Minotaur), they've mainly been an enemy to both Thor and Lady Thor. Agger, in turn, has since branched out to the Immortal Hulk. In the Ultimate Marvel continuity, Roxxon was more of a general villain to almost every hero, being the cause of how most heroes got their powers and behind many atrocities. As the Ultimate Marvel line dwindled down, Roxxon was exclusively a problem for Miles Morales/Spider-Man and his friends. So much so, in the video game Spider-Man: Miles Morales, Roxxon and their Corrupt Corporate Executive Simon Krieger are the main antagonists. They would again become a pain for Miles in the 616-continuity in Champions (2020), along with the other Champions.
  • The general public now knows Ronan the Accuser as the villain of the 2014 Guardians Of The Galaxy film, but he actually debuted as a Fantastic Four antagonist, and is now in fact not much of a villain at all in the comics (to the point of teaming up with the Guardians in one of his most recent appearances)
  • Following the disbanding of the Fantastic Four after Secret Wars (2015) many of their enemies went on to face other heroes. Terrax went up against the X-Men.
  • Madame Masque for most of her existence was an Iron Man villain, but since the 2010s, she has become the Arch-Enemy of Kate Bishop (purely out of spite because Kate once knocked her out and stole her costume). First Masque antagonized Kate in her solo arc in Hawkeye (2012), then again in Hawkeye (2016), and again in West Coast Avengers (2018). In the the 2020s, she also picked up a few magic tricks and ended up tangling with Dr. Strange.
  • Alex Wilder, the original leader of the Runaways, was revealed to have been a mole all along during The Good Die Young arc, fanatically loyal to his parents and the Pride's cause, only to be killed shortly after by the Gibborim. When he was resurrected over ten real world years later, he would eventually become a villain in Power Man and Iron Fist. The same story had him in an Evil Versus Evil situation with Spider-man villain Tombstone, with Luke and Danny caught in between. In final issue, as they're beating each other up, frustrated Luke even wonders why he keeps having to deal with Tombstone all of sudden.
  • Chemistro was originally an enemy of Power Man and Iron Fist, but over time moved on to fight other heroes like Iron Man and the New Avengers.
  • Invoked in Ms. Marvel (2014). One 2018 story has the Shocker, normally a C-list Spider-Man villain, get so tired of getting smacked around by everyone in New York City that he upped and moved to New Jersey and made himself Kamala's new arch-nemesis because dealing with a teenager is much easier than the rest of New York. Kamala, who is already dealing with usual teenager problems and wonky powers, is not amused.
  • During the 70s, there was a giant robot known as Red Ronin, who was designed to battle Godzilla. It did so and later turned into an ally for the giant green lizard. When Marvel lost the rights to Godzilla, Red Ronin ended up being turned into a basic foe for the Marvel Universe as a whole, usually taken over by some random villain to wreck havoc and let the heroes trash. Doctor Demonicus was also created as a Godzilla villain, but went on to face off against Iron Man and the West Coast Avengers when the Big G’s rights returned to Toho.
  • Taskmaster debuted as an Avengers foe, and while still commonly associated as a villain to them, he's also antagonized individual members, particularly Captain America. He's also been a villain to Scott Lang, the latter even thinking of him as his Arch-Enemy (he isn't), and has tangled with Spider-Man a number of times. He's also known for his longtime rivalry with Deadpool. Really, all that matters is if he's getting paid, which naturally leads to him fighting a number of different people.
  • Cloak and Dagger's 2018 run had them menaced by Mr. Negative, traditionally a Spider-Man foe. Thematically, he makes a lot of sense, as the duo represents darkness and light much like Mr. Negative himself. It also helped that they had previous history with him through guest spots in Amazing Spider-Man, including a period of being mind-controlled into working for him, meaning they now have a stronger connection to him than Spidey does. It was also revealed in the Dark Reign: Mr Negative miniseries that Mr Negative got his powers in the same experiment as Ty and Tandy.
  • Selene is normally a New Mutants or X-Men villain but she's also fought Captain America and his friends even making a big debut to his comics by killing the Hydra version of Captain America.
  • Sunset Bain was introduced as a Machine Man villain, but has since taken to menacing Iron Man. The fact that she runs a rival electronics company made her a natural fit.
  • Many of Marvel's 2019 annuals were themed under the banner Acts of Evil, with no actual story throughline, but a theme of heroes fighting villains they would normally have nothing to do with, such as Ms. Marvel versus the Super-Skrull, the Punisher versus the Brood, Moon Knight versus Kang the Conqueror and She-Hulk versus Bullseye.
  • Captain America:
  • Rawhide Kid once fought a villain wielding a paralysis gun called the Scorpion. The Scorpion later broke jail, changed his alias to Sting-Ray, and battled another western hero, the Phantom Rider.
  • The Extreme Carnage event puts the Friends of Humanity, usually an anti-mutant extremist organization, into the symbiotes' rogues gallery. In-universe, Iron Man notes how strange it is for an old mutant hate group to suddenly go after aliens. One can only surmise, assume, or speculate is that the F.O.H. are unable to go after Krakoa with starting an international incident nor they can afford the luxury or privledge of joining Orchis. So, they could only go after the next best thing: aliens.
  • The Wrecking Crew debuted as Defenders villains (with the exception of the Wrecker, who was a preexisting Thor baddie), but over time became better known as enemies of the Avengers. In general, they tend to be a fairly popular choice for smaller scale Villain of the Week plots, as their comparatively meager ambitions (usually desiring money rather than world conquest or galactic genocide) makes them perfect filler villains for characters like Wolverine and She-Hulk.
  • The Griffin was created as a Beast villain during the brief period where Hank had a solo feature in Amazing Adventures. After Beast's series was cancelled, Griffin drifted throughout the Marvel Universe as an all-purpose villain of sorts, facing the likes of Spider-Man, Wonder Man, the Champions, Namor and various incarnations of the Avengers. He was also eventually revealed to be the father of Yo-Yo Rodriguez in Secret Warriors.
  • Kulan Gath was originally a foe of Conan the Barbarian in the Conan comic books. He later makes his way into the modern world where he's a foe of the Avengers, X-Men, Spiderman and Doctor Strange all at the same time! And for even further transplanting, when Red Sonja became a Dynamite Comics property - he went over there to be her Arch-Enemy and still occasionally shows up to give her grief. More recently, he's the Big Bad of the Savage Avengers - once more showing that he's a power that can't be dealt with by a solo hero.
  • During The Clone Saga, there was a man named Judas Traveller, who tailed Peter Parker and Ben Reilly before disappearing near the end of the event. After laying low for 25 years, he resurfaced over in X-Men’s The Krakoan Age era as a part of the anti-mutant organization ORCHIS.
  • ORCHIS executive Fei Long first appeared as part of The Krakoan Age and while he's still an enemy to the X-Men, he's also got beef with Tony Stark by killing one of Tony's friends and taking over Stark International then using Iron Man technology in Orchis's next-generation sentinels. Plus he blames Tony and the other Avengers for not helping him colonize Mars first before the mutants went and terraformed the planet.
  • The Vox were created as part of the Death of the Inhumans event which essentially put the entire franchise on a bus by wiping out several of new Inhumans created during the Inhumanity and nearly wiping out the Inhuman royal family. Since then, they haven't been seen except for one particular Vox, Vox Supreme who was the Big Bad of Carol Danvers/Captain Marvel in her 2019 volume.
  • Heroes Reborn (2021) has multiple instances of this, as it revolves around a world where the Squadron Supreme have supplanted the Avengers as Earth's premier superhero team:
    • Batman expy Nighthawk gains most of Spider-Man's traditional Rogues Gallery, with Norman Osborn serving as his The Joker-like arch nemesis.
    • Superman expy Hyperion gains Doctor Doom, the Hulk, the Beyonder, Annihilus and Ultron, with most of them positioned as pastiches of traditional Superman rogues (the Hulk as Bizarro, Mr. Beyonder as Mr. Mxyzptlk, General Annihilus as General Zod and Ultron as Metallo).
    • Wonder Woman expy Power Princess gains traditional Thor baddies Mangog, Gorr the God Butcher, Ulik and Hela, as well as traditional Avengers Janet Van Dyne, Tigra and Hercules (serving as pastiches of Wonder Woman's foes Giganta, Cheetah and Hercules, respectively), traditional X-Men members Phoenix and Magik, and the Venom villain Knull.
    • The Flash expy the Blur gains the Silver Witch (a version of Scarlet Witch who absorbed the speed of her brother Quicksilver) as his nemesis, and also fights Ursa Major (here a stand-in for Gorilla Grodd).
    • Green Lantern expy Doctor Spectrum gains a bunch of cosmic villains like Thanos, Ego the Living Planet, the Super-Skrull, Ronan the Accuser, and despite not being cosmic-themed, M.O.D.O.K. and the Circus of Crime. Uatu the Watcher also serves as another of his adversaries despite mostly being a good guy in the mainline universe.
    • As a team, the Squadron also face the Masters of Evil and Mutant Force, enemies of the Avengers and Captain America, respectively.
    • Teen Titans/Young Justice expies the Young Squadron battle Deadpool and the Wrecking Crew.
  • In Identity Crisis (1998), two of the foes Spidey faces in trying to clear his name is Bloodstream and Roughhouse, who are normally Wolverine's sparring partners.

    Films 

Films

The following have their own pages:


  • Kingpin is the primary villain of Spider-Man: Into the Spider-Verse. But while he's always been a major enemy of Peter Parker in the comics, he's rarely come into contact with Miles Morales, the central protagonist of the film. The Ultimate Kingpin was also killed off long before Miles was introduced.
  • Viper started off as a Captain America foe and is usually an enemy of Nick Fury and S.H.I.E.L.D. as well (to the point that she's now known as Madame Hydra). Despite this, she is one of the antagonists in The Wolverine. Understandable since despite her connections to Captain America and S.H.I.E.L.D., she has appeared in several notable Wolverine storylinesnote .

     Video Games 

Video Games

     Western Animation 

Western Animation

  • Avengers Assemble uses Impossible Man, another Fantastic Four enemy, as well as Doctor Doom. The Cabal, originally created as the Evil Counterpart of The Illuminati, act as the first main antagonists, founded by Captain America's Arch-Enemy Red Skull and his other enemy MODOK (whom is more acknowledged here by his later encounters with Iron Man), with Dracula, Sub-Mariner rogue Attuma, and Hyperion (a member of the Squadron Supreme, though his overall depiction is closer to the villainous Squadron Sinister version) also added. Later arcs find ways to add Thanos and the Black Order (though Crisis Crossover events do see Thanos face the team in the comics despite being better known for his encounters with cosmic heroes), a new Cabal featuring the Leader, Zola, Enchantress, and Loki, all enemies of Hulk, Captain America, and Thor, though Loki was the Avengers' original Starter Villain, and Madame Masque, whom normally faced Iron Man and Hawkeye (Kate Bishop), was used in a season that was heavily centric to Black Panther, just to name a few, that same season mainly having his enemy Erik Killmonger as the main antagonist.
  • The Avengers: Earth's Mightiest Heroes essentially made the Black Panther villain Klaw into an Ant-Man foe, as Ant-Man is the one who mangles his hand and later comes up with the strategy to defeat him. This left Black Panther without an Arch-Enemy or someone to yell You Killed My Father at, so the writers made Man-Ape into his father's murderer instead. Klaw does still participate from the shadows, but its only because T'Chaka's fight with Man-Ape was really a Trial by Combat fight to the death for the throne, where Klaw's sabotage gave Man-Ape the advantage and victory.
  • The sole costumed supervillain to show up in the first season of Hit-Monkey is Lady Bullseye, who is an enemy of Daredevil in the comics.
  • Hulk and the Agents of S.M.A.S.H. has put the Hulks up against Annihilus, Blastaar, and Ego, the Living Planet, all longtime Fantastic Four headaches, and Doctor Doom above especially. Bonus points for X-Men foe Sauron. However, The Man Behind the Man villain of the series is the Leader, who is a Hulk villain.
  • In The Incredible Hulk (1982), some episodes pit the Hulk against other heroes' enemies.
    • Spider-Man foe Doctor Octopus is the villain in "Tomb of the Unknown Hulk".
    • "Prisoner of the Monster" features Iron Man adversary Spymaster as the antagonist.
    • "Bruce Banner Unmasked" has the Hulk fight the Puppet Master, whose usual adversaries the Fantastic Four get no acknowledgement aside from his step-daughter Alicia Masters having a bust of the Thing among her statues of Marvel characters.
    • The forces of Hydra are fought in "Enter: She-Hulk", when the organization is ordinarily an enemy of S.H.I.E.L.D. or Captain America.
  • The Mad Thinker and Awesome Android pop up in Iron Man: Armored Adventures as enemies (and classmates) of Tony and his buddies. In the comics, they're traditionally enemies of the Fantastic Four, even in the Ultimate Marvel universe (which the show went with, depicting the Mad Thinker as a teenaged girl, instead of an adult man like the original). And then there's Doctor Doom and Magneto, who both show up in Season 2 (Magneto's appearance, in fairness, also features Professor X and Jean Grey, both of whom were from the X-Men).
  • The “Armor Wars” two-parter in Iron Man: The Animated Series sees the title character hunting down various armored characters from across the Marvel Universe, including the Beetle (originally a Human Torch villain and best known for fighting Spider-Man) and Stilt-Man (an enemy of Daredevil).
  • Marvel's Spider-Man has two examples:
    • The Blizzard used for this series, Randall Macklin, is a one shot enemy of Iron Man, who does not appear in this episode, and his origin involves Harry and Peter's invention, likely in reference to Blizzard sometimes facing Spider-Man.
    • Absorbing Man is normally a foe of the Hulk and Thor, the former having appeared in only the Halloween episode, and the latter only appearing in later seasons.
  • The Marvel Super Heroes had an episode of the Sub-Mariner segment feature Doctor Doom as its villain. Doom's usual enemies the Fantastic Four couldn't appear because of rights issues (having already been used by Hanna-Barbera for The Fantastic Four (1967)), so they were replaced by the original roster of the X-Men, albeit referred to as the Allies for Peace.
  • The true villain of the first season of MODOK is ultimately revealed to be Hexus the Living Corporation, who originated in Grant Morrison's Marvel Boy limited series.
  • Moon Girl and Devil Dinosaur (2023):
    • Allison Dillon / Aftershock serves as the main villain Lunella and Devil face in the pilot episode. The character was originally created as a villain for Spider-Girl.
    • The Beyonder, a universe-wide threat primarily known for his association with heroes like Spider-Man and the Avengers, serves as a recurring character throughout the season despite having no real connection to Lunella in the comics.
    • The episode "Today, I Am a Woman" sees Lunella clash with Odessa Drake, a rival and ex-lover of Black Cat.
  • Doctor Doom was featured as a villain in Spider-Man (1981) and its related series Spider-Man and His Amazing Friends, neither of which acknowledged his usual enemies the Fantastic Four. Spider-Man considered him his Arch-Enemy instead of Doctor Octopus or Green Goblin in those series.
  • Spider-Man Unlimited had Spidey going up against the High Evolutionary, normally a cosmic Marvel villain (though he has ties to the X-Men; he was once a colleague of Spidey's foe Jackal in the comics, but that was about it for pre-existing connections).
  • The Spider-Woman episode "Realm of Darkness" had Spider-Woman fight Dormammu, who was traditionally an enemy of Doctor Strange.
  • Taken to the extreme in Ultimate Spider-Man (2012), as part of the show's apparent attempt to be as different as possible to the traditional Spider-Man formula. So far, the show has largely avoided classic Spider-Man antagonists, the only ones showing up after more than twenty episodes being Venom (with Harry Osborn as the host instead of Eddie Brock, though the symbiote later goes to Flash Thompson and turn him into Agent Venom as it does in the comics), Doctor Octopus, Norman Osborn (who doesn't become the Green Goblin until the season finale) and Sandman. The other episodes involve either crossover episodes with other heroes involving villains from the guest-star's rogue gallery (Living Laser for Iron Man, Loki for Thor, Zzzax for the Hulk, Mesmero and Sabretooth for Wolverine) or villains from other Rogues Galleries who are treated like they were Spider-Man's regular villains (Doctor Doom and the Frightful Four, whom are Fantastic Four villains, Batroc the Leaper, whom is a Captain America villain, Taskmaster, who debuted as an Avengers villain, Whirlwind, originally a foe of Ant-Man, the Juggernaut (though justified in that there was one notable comic story where Spider-Man did fight Juggernaut)...) As an added twist, some of Spider-Man's foes are now tied to other heroes, such as Kraven being the one who killed White Tiger's father, and the Scorpion being from the same mythical city as Iron Fist. Even though the show did eventually bring in more Spider-Man rogues and storylines, the aforementioned Taskmaster becomes The Heavy in the first half of season 3, where he recruits potential new SHIELD heroes to spring Green Goblin from prison, leading to Goblin's travels across the Spider-Verse, and in season 4, HYDRA and its leader Arnim Zola, both foes of Captain America and SHIELD (the latter being the mentors to Spider-Man and other heroes) begin to back the Sinister Six, and Crossbones, another foe of Cap and SHIELD, is selected by HYDRA to replace Dr. Curt Connors as the Lizard when Spider-Man successfully cures Connors for good.

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