In the United Kingdom, Mars had a popular advert for Milky Way that involved an (anthropomorphised) blue car racing a red car. A year or two later, they revamped their campaign by remaking the same advert...but now with blue and red spaceships racing IN SPACE!
Dragonball Z Abridged loves this trope. Jeice is from Space Australia, Vegeta knows about The Three Stooges thanks to Space Hulu, Zarbon wants to call his girlfriend over Space Skype. Oh, and when Freeza goes to Earth, he's going to pick up some space eggs, some space milk, and Blow It The F-ck Up.
Also Piccolo switched to Spacebook from Myspace "a while ago."
Pink Unicorn:"Charlie, we don't have much time! We have to get to the moon!"
Blue Unicorn:"In OUTER SPACE!!!"
Blue Unicorn:"I don't know why I yelled that!"
Stage-Select subcomic Here is a Questiondiscussed this for one strip, suggesting the phenomenon of this trope in the 1960's was due to the excitement of the space race. Then the money grubbing author decides to hop on the bandwagon and reformatted the comic into - you guessed it - Here is a Question◊ IN SPACE! A mild Rage Against the Authorlater◊, the comic returned to normal.
Given one of its artists, Natasha Allegri, is Bee and Puppycat's creator, the story told by Puppycat in episode 2 wouldn't be out of place in Adventure Time, what with the Functional Magic and kingdoms named after attributes. The show itself is a bit different.
Any form of space travel, really. HUMANS IN SPACE!
The OCR Physics A level in England. A levels have two sections; AS and A2. When asked what was covered in A2, one troper's teacher replied, "It's basically AS module one IN SPACE."
This sort of premise has been seen in venture capital investing, in which it becomes shorthand to describe some new idea as "X for Y" where X is some preexisting thing and Y is some new demographic. (For example, "Groupons for Moms".) Venture capitalist Ethan Kurzweil has written an article decrying this tendency as lazy and possibly detrimental to creativity.