When a character's pregnancy is complicated by supernatural means - be it Bizarre Alien Biology, Functional Magic, or even through a Mad Scientist. There are three ways this could work:
- Supernatural conception: The pregnancy is unnatural from the very beginning, such as Jesus's conception in The Bible. Half Human Hybrids and babies conceived through Mpreg are examples of this. This is normally a good time to exclaim "But I Can't Be Pregnant!," where there is understandable reason to be surprised about the pregnancy.
- Supernatural pregnancy: The baby is conceived normally, but during pregnancy something mystical happens to the mother and/or the fetus. Unfortunate women subjected to experimentation either through a Mad Scientist or a Back-Alley Doctor can end up with this.
- Both. The baby is conceived and carried to term through supernatural means.
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- Horrific example from Berserk: Guts and Casca's child, conceived in their moment of love by the waterfall, was corrupted by the demonic seed of the newly-born Femto, who raped Casca during the events of the Eclipse.
- From the same series, Ganishka's demon-soldiers are created by dropping heavily-pregnant women into vats of demonically-charged amniotic fluid which instantly corrupts and mutates the foetus into a demon, who then claws and bites his way out of the womb.
- In the 3rd OVA to Fushigi Yuugi, Miaka and Tamahome conceive a baby on their wedding night. Three months later, Mayo finds the Book of the Four Gods again, and the pregnancy is supernaturally transferred to Mayo (while Miaka goes into a coma), because Mayo has such strong feelings for Tamahome. (She takes full advantage of the pregnancy and her status as Priestess, much to Tamahome's dismay.) Even though it seems all is lost, it's actually a Xanatos Gambit on the part of Miaka, in order to save the Universe of the Four Gods. After the fetus is used as a Living Macguffin in a Metaphysical Place to summon Suzaku, the baby is transferred back into Miaka, who wakes up and the pregnancy continues normally. (Mayo, too, goes on to live a normal life.)
- In Naruto female jinchuuriki have pregnancies that last ten months, during which the seal binding the bijuu to their body weakens to the point that a seal master has to prevent it breaking during the birth. At least one child born this way also had a distinct birthmark as a result, namely Naruto's whiskers.
- Shukaku was sealed into Gaara while his mother was still pregnant with him. Yashamaru claims the sealing drove her insane and ultimately was responsible for her death. Gaara was actually born premature and she died due to the strain.
- The Invisible Woman of the Fantastic Four had already had a difficult pregnancy with her first child, Franklin. Susan's second child was conceived in the Negative Zone, and resulted in a stillbirth.
- The plot of the comic book series America's Got Powers begins when an alien crystal falls to Earth and gives off a burst of energy. All of the pregnant women within range, regardless of how far along they were, immediately give birth to fully-developed, healthy, super-powered babies.
- The Boys: Billy's wife dies when her superpowered fetus (she'd been raped by a super) explodes out of her uterus, floating in the air and firing Eye Beams. He kills it with a table lamp.
- Rosemary's Baby involved a young woman getting prescribed mysterious drugs by her doctor during her pregnancy, which she comes to suspect aren't legitimate treatments but something more sinister... but it is too late, and she births an Enfant Terrible (implied as possibly The Antichrist).
- In The Phantom Menace, Shmi Skywalker says that Anakin has no father, which Qui-Gon assumes to mean that he was conceived by the will of the Force. In Revenge of the Sith, Palpatine's discussion about Darth Plagueis include a pointed comment that suggests Plagueis's experiments may have been responsible for Shmi's pregnancy.
- Blade's mother was bitten by a vampire not long before he's born. The result: He's a Dhampyr.
- Tangled: The pregnant queen becomes deathly ill, and the kingdom's soldiers seek out a mystical flower that could heal her. When she ingests it, she is cured, and her daughter is born with hair with healing powers.
- Alcmene in The Legend of Hercules.
- Aurora in Babylon A.D. is pregnant while never having been with a man. It turns out her father used gene therapy to "enhance" Aurora to get pregnant at a certain time in order for the Noelites to become a "bona fide religion" by having a virgin birth. Aurora ends up dying immediately after giving birth to twins (black and white), as she was programmed to do, and the protagonist ends up adopting and raising them.
- In Into the Woods, the Baker's Wife goes through an accelerated pregnancy, which is promptly lampshaded by a blunt "Well, that was quick." A more modest interpretation is that reversing the curse simply made it as if the curse was never cast in the first place.
- In Angel this happens to Cordelia twice and Darla once.
- In an early episode Cordelia has a one-night-stand with a guy who turns out to be a human 'donor' for the sperm of a demon he worships. It ensures the human is extremely lucky with women and that any woman he sleeps with becomes immediately pregnant with the demon's offspring, carrying the offspring to term in only a few days and dying in the process of giving birth. Cordelia is saved just before she gives birth.
- Cordelia was used by a Power That Was as an incubator for that Power's own birth after that Power had instigated several miracles which were pre-requisite for Its own birth.
- Vampires can't have children, but Angel and Darla did, after having both been brought back from Hell. The baby was human with certain, unexplained demonic connections. Because her body was dead during the pregnancy, Darla was unable to give birth so had to stake herself to save the baby. The pregnancy and birth was also one of the miracles required by the Power That Was for It to be born as it required this child, Connor, to sire it into being via Cordelia's body.
- Tim doesn't believe that Corinne's baby is his because she's showing after only a few weeks of pregnancy. She insists that it's Tim's baby, and ends up giving birth after only a month or so. It turns out that the baby is possessed by the devil.
- Mary is pregnant with Burt's child, but she's not sure it's his - she conceived at around the same time when he had been kidnapped by aliens & replaced by an alien doppelganger, so it might be half alien.
- On Once Upon a Time, Cinderella was pregnant when the Dark Curse brought her to Storybrooke, where because of being essentially frozen in time, she was pregnant for 28 years. Delivery was also complicated because she had tried to renege on a deal with Rumplestiltskin.
- In season 9 of Stargate SG-1, Vala is impregnated by the Ori (god-like aliens) with their version of the Messiah. For a while, Vala just knows that she didn't have sex but she isn't sure how it happened. It isn't until late in the pregnancy that she finds out the child is "the will of the Ori."
- In Star Trek: The Next Generation Deanna Troi is impregnated by glowing space energy and gives birth to a mysterious rapidly-aging child, an alien life form that comes and goes this way.
- In Doctor Who, companion Amy's pregnancy during the Eleventh Doctor's era. The baby was conceived aboard a TARDIS in flight, giving her *three* parents (and primitive Time Lord DNA), and Amy was held prisoner during her pregnancy so that the Big Bads could steal her baby.
- In Fringe, Fauxlivia is subjected to horrifying medical experiments to artificially accelerate her pregnancy, both because the pregnancy would kill her and because Walternate wants the baby's blood to power a Doomsday Device.
- A classic example occurs early in the run of The X-Files, as Scully finds herself impregnated by aliens. Towards the end of the series, she has another Mystical Pregnancy.
- In the new Battlestar Galactica, Starbuck's ovary is harvested without her knowledge or consent so that the Cylons can create more hybrids.
- In Being Human, Nina discovers the hard way that her birth control doesn't work when she's a werewolf. The pregnancy progresses at about twice the normal rate, and the baby is the subject of an ancient vampire prophecy.
- Owen's parents in A Prayer for Owen Meany claim he was a virgin birth.
- In Twilight: A character note ends up impregnated by a vampire note and giving birth to a Half-Human Hybrid dhampyr that ends up growing supernaturally quickly.
- In the Elder Races stories by Thea Harrison, the pregnancy resulting from the marriage of Dragos Cuelebre and Pia Giovanni was complicated to say the least. For starters, Dragos is actually an immortal dragon in human form and Pia is the offspring of a human and a unicorn in human form; Pia herself can turn into a unicorn.. Since the pregnancy was utterly unprecedented, no one knew for sure how long it would go on or what form the offspring would take. Fortunately at nine months, the fetus transformed itself in utero to a human baby and was born normally
- A Song of Ice and Fire: Daenerys's pregnancy starts off normal, but after she asks a witch to perform Blood Magic to save her husband, the witch complicates Daenerys's pregnancy, leading her to birth a horrific reptilian baby that may have damaged Daenerys's womb and rendered her incapable of bearing children forever. (Or did it?)
- In The Mortal Instruments: Jocelyn's husband Valentine experimented on her while she was pregnant both times, giving her daughter Clary angel's blood and her son Jonathan Christopher demon's blood, resulting in supernatural powers.
- Thief of Time: the Anthropomorphic Personification of Time goes through one of these, essentially having the same birth twice, with the end result being one soul going in two children. Nanny Ogg, who was the midwife, was quite surprised, as she told herself (literally).
- In Dune, Lady Jessica drinks and transforms the Water of Life for the Fremen seitch while pregnant with Alia. Due to that Alia is born with uncanny psychic powers and the memories (and as seen later, multiple personalities) of all her ancestors—a condition the Bene Geserit foresaw (or probably had seen from prior experience) as coming from such circumstances, to be avoided as "abomination".
- In The Ramayana, the god Vishnu turns himself into celestial porridge (no, seriously) that King Dasaratha is supposed to feed to his wives. All three of them subsequently give birth to sons that are endowed to different degrees with Vishnu's essence.
- In the Forgotten Realms Pools of Radiance trilogy, Kern's mother was affected by magic during her pregnancy. Kern gestated at an amazing rate, but didn't age any faster. He's also nearly immune to magic, including healing magic and other helpful magic, which appears to be a result of what happened to his mother.
- From The Bible:
"How will this be," Mary asked the angel, "since I am a virgin?"The angel answered, "The Holy Spirit will come on you, and the power of the Most High will overshadow you. So the holy one to be born will be called the Son of God."- Luke 1:34-35
- Jesus' mother Mary was an unwed virgin. She became pregnant directly by the power of God, without the need for sex.
- The Qur'an also ackowledges the birth of A´ssa (Jesus' name in Islam) from Mariam (Mary) as a virgin birth.
- Dr. Hojo, the Mad Scientist from Final Fantasy VII, tampered with his pregnant wife and unborn son by injecting cells from an Eldritch Abomination into her body. The result was the most powerful Super Soldier in the setting, who eventually defected to the side of said abomination and became the Big Bad of the game.
- Ryusei Date gained Psychic Powers as a result of experiments that were performed on his mother when she was pregnant with him.