"I'm sorry, no, I won't take it. If we accept orc zombies, then we open the gate to all kinds of crap. What's next? Centaur dragons? How about demon fairies? Maybe buffalo elves? Heck, why not whale vultures? I'm going to make a stand for plausible monsters everywhere. Who's with me?"The logical conclusion of Half-Human Hybrid, Monster Mash, and Mix-and-Match Critters. A Hybrid Monster is a creature made up of two or more mythological, alien, monster, or fantasy creatures... or all of the above! It's common for these creatures to be more powerful than the separate component creatures. Despite the near infinite combinations possible, there's only a few variants of these creatures:
- Natural Breeding: Two creatures, perhaps themselves once human or Half Human Hybrids, or completely different species (never mind races) get it on and produce a child. Maligned Mixed Marriage optional. Expect this to be part of a Mary Sue's parentage. Common subtypes include: Vampire-elves, vampire-werewolf, dragon-elf, angel-demon, etc.
- Transformation: An already non-human creature gets an incomplete Baleful Polymorph, is infected with The Virus, bitten by a werewolf, or grafted with cybernetics or subjected to genetic engineering. What happens here is you have a "common" base type which gets superseded by a second one. Common subtypes include: Vampire-elves (again), <<species>>-skeleton, <<species>>-zombie, cyborg-demon (more common than you'd think), and mutants of any such species in general.
- Fusion Dance: Two already existing creatures become one already existing creature. Often from a spell Gone Horribly Wrong, Merging Accident, or a Teleporter Accident. Common subtypes include: Tuvix. End of line.
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Anime and Manga
- Mahou Sensei Negima! has the Griffin Dragon that Yue Ayase takes down with a ceremonial dagger.
- The Darkness of the Book of Darkness at the end of Magical Girl Lyrical Nanoha A's, likely a result of the Wolkenritter collecting Mana from alien magic beasts as well. Its body included the black wings and upper torso of Reinforce, the rocky protrusions and and metal plates of the giant turtle-like beasts, and the tentacles of the Sand Worms, along with other parts like giant red horns and spider-like legs it got from who-knows-where.
- The monster from WXIII: Patlabor the Movie 3 is part human, part alien & later absorbs a Humongous Mecha as well. It also inexplicably has fish & lobster bits.
- Ranma ˝ has Pantyhose Taro's cursed form, which in his first appearance is a Yeti/Bull/Crane/Eel hybrid. By his second appearance he has also added Octopus.
- In Pokémon Special, there is a stone statue in Eterna City that features a cross between Dialga and Palkia. This is later explained as people once thought the two beings as one.
- The Hybrid Bakugan of Bakugan were created from the collision of two elemental planes. As a result, all six of them are sort of cruel mockeries of their combined elements with personalities to match.
- Digimon Adventure 02 took quite a shine to this trope - it pretty much started with Chimeramon (and by extension, its evolved form Millenniummon from the WonderSwan games), then proceeded to combine this with Fusion Dance for Paildramon and Silphymon.
- The Nyokai from The Twelve Kingdoms. The more varied animal parts they have, the better. Special mention goes to Taiki's own, Haku Sanshi: she has the head and torso of a white-haired girl, the eyes of a fish, the tail of a lizard, and the lower body of a leopard.
- Even her personality is Hybrid. The transfer to Wa (Neo-Japan) changes her mode of thinking from gentle mama-tiger to homicidal guardian who knows how to cause car accidents. And somehow, the demon lord that guards Taiki (don't ask) doesn't seem to care...
- In the Itadaki! Seieki♥ the main female character, Mari Setogaya, is a half-Vampire, half-Succubus.
- Marvel Zombies had just about every Marvel Comics hero and villain turn into a zombie. Which was a space virus. We'll let you ponder the ramifications of Zombie Wolverine, Zombie Human Torch, and Zombie Hulk for yourself.
- Disregarding the whole "space alien" backstory thing, Two-Edge from ElfQuest would technically qualify, being half-elf, half-troll.
- The titular Monster Plus is a one-man Monster Mash - he's a vampire werewolf Frankenstein's monster zombie mummy witch doctor. Originally, he was just a Frankenstein's Monster, but when you get into the kind of scrapes he does you pick up some unique skillsets and/or bite marks.
- You could arguably include his enemies Hitlerfist and Supermane; Hitlerfist is the monster with Hitlers for hands, while Supermane is, well, Superman with a lion head.
- Hulkling of the Young Avengers is Half-Kree and Half-Skrull.
- The French comic Zombillenium concerns an horror-themed amusement park run by actual monsters. Due to managers disagreeing which ride he needs to be stationed to on his first day (a werewolf and a vampire who were both short-staffed and kept biting him alternately), the hero ends up looking like a traditional Big Red Devil.
- Malphast from PS238 is the child of a demon and an angel.
- Nina Price, Vampire by Night, a Marvel Comics character created by Jeff Parker and Federica Manfredi in the anthology book Amazing Fantasy, and subsequently appearing in Howling Commandos, is the niece of Jack Russell, Werewolf by Night, who inherited the family curse. And then got bitten by a vampire. She's human during the day, a vampire by night, and a white wolf at full moon.
- In Pokémon Reset Bloodlines, MissingNo appears for the first time taking the form of an amalgam of Dialga's head, Palkia's arms and Origin Forme Giratina's body, albeit having each of those parts of a color different from the originals.
Films — Animated
- The talking-donkey/dragon hybrids from Shrek 2 qualify, though as they're all fluffy little foals they're hard to see as monsters.
Films — Live-Action
- This is the driving force behind the plot of Underworld, Lucian wants to create a hybrid of the (biological) vampires and werewolves so he can finally win the war between both species in his (the werewolves) favor.
- Underworld: Evolution gets interesting in this regard. While Michael is a Werewolf-Vampire hybrid, Marcus becomes a Vampire-Werewolf hybrid (which means he gets wings, but is still nocturnal). Selene herself gets "hybridized" with Alexander's blood, making her not so much a Vampire-??? as pure badass, as well as immune to sunlight.
- Underworld: Awakening features Selene and Michael's daughter who was conceived after they had both become hybrids themselves, so she was born as a hybrid of two hybrid species. The Dragon to that film's Big Bad was also a hybrid of sorts, being a werewolf whose DNA had been spliced with something that made his wolf form twice the size of a normal werewolf and made him immune to most of the traditional werewolf weaknesses.
- The Predalien in Aliens vs. Predator: Requiem, although he is technically an alien born from a predator body and not a pure hybrid.
- Technically, the warrior aliens we are so used to seeing in the Alien series would be a alien-human hybrid (The Newborn from Alien: Resurrection also would count), and the creature from Alienł would be an alien-dog hybrid.
- By that logic, The Proto-Xenomorph "the Deacon" in Prometheus would count as well, being an alien born from an Engineer.
- The Fly (1986) has Brundlefly, a six foot, 185 pound, acid spwewing man/fly hybrid.
- Splice has Dren, a female creature that is part human, and any number of other animals, depending on how many 'plug and play' samples were inserted into her DNA at the time of her conception.
- In The Monster Club, vampires, werewolves and ghouls can all mate together. These hybrids can then mate to produce further hybrids.
- In The Omen films, Damien - The Antichrist - looks human, but he doesn't qualify as one at all. His father is the Devil and his mother was a jackal.
- Older Than Radio: In Alice's Adventures in Wonderland, in addition to the Gryphon, there's the Mock Turtle, a turtle with a calf's head, hooves, and tail. (This is likely because mock turtle soup, which the Queen of Hearts says is made from mock turtles, was once made from the discarded parts of a calf, much like the discarded parts of cows are used to make low-grade hamburger in modern times.)
- The City of Dreaming Books has harpyrs, a cross between a harpy and a vampire.
- The Xanth series abounds with this, due to the magical love springs which created the world's Half Human Hybrids in the first place.
- Although the White Witch from The Chronicles of Narnia claimed to have at least partial human ancestry, she was actually a hybrid of giant and jinn (genie).
- In Christopher Stasheff's A Wizard in Rhyme series, there's a dracogriff. He's half griffin, half dragon. Unfortunately, this is not quite as awesome as it sounds, since griffins and dragons are bitter enemies and he's hated by both.
- Harry Potter: The Ministry of Magic has explicitly outlawed experimental cross-breeding. Not that this prevented Hagrid from breeding Manticores with Fire Crabs to produce Blast-Ended Skrewts.
- In another book, the Ministry has take into custody a fire-breathing chicken.
- In L. Frank Baum's The Magic of Oz, a boy and the Nome King (using a magic word that lets the user shape-shift anyone however they want) transform themselves into Li-Mon-Eags—"creatures with the heads of lions, the bodies of monkeys, and the wings of eagles as well as having" ball-shaped tails.
- In Heart of Steel, Alistair's second (and ultimately much less disastrous) gift to Julia is a creature assembled from the torso and arms of a gorilla and the everything else of a pony. After a bit of trepidation, Julia ultimately names it Cuddles.
Live Action TV
- The cockatrice on Merlin was originally going to be one of these - ◊. But somewhere along the way it just became some kind of dinosaur thing. The makers apparently saw sense and cast the creature pictured as the Questing Beast, of which it is a fairly mythologically-accurate portrayal.
- Big Bad Burajira Tensou Sentai Goseiger uses these as his MOTWs. Examples include an Ortaurus (Orthus + Taurus) and a Uniberus (Unicorn + Cerberus).
- Power Rangers Mystic Force has Phineas, who was a Troblin. Half troll, half goblin. Surprisingly nice guy, all things considered.
- Eve, the Mother of all supernatural monsters from Supernatural, is finally released from Purgatory and spent some time combining various monster traits. Dean calls them Jefferson Starships, because they're horrible and hard to kill.
- Besides the aforementioned Tuvix, Star Trek: The Next Generation featured at least one half-klingon half-romulan. Also, of most species featured in the Borg's species registry, there exists (or existed) a cyborg-zombie variant.
- Except for the Kazon, the only species ever deemed unworthy of assimilation. In a universe with thousands of species, that's a major burn.
- In Grimm, one episode features a hybrid-Wesen, created after a Genio Innocuo mother felt they were too passive-aggressive and spliced her son's genes with that of a Lowen. Unfortunately, this created a Jekyll & Hyde situation as since the Genio Innocuo are naturally competetive, the Lowen side would manifest to murder their competition.
- The Ultra Series features a few, usually created by the Big Bad from previous monsters in the show.
- Jumbo King was the final monster of Ultraman Ace and made from Cowra's head, Mazarius' body, Mazaron-Man's legs, and Unitang's arms.
- Ultraman Taro's Tyrant (who is easily the most popular of the bunch) is the result of the spirits of deceased, vengeful monsters merging themselves to destroy the Ultra Brothers. It has Red King's legs, Alien Icarus' ears, Bemstar's belly, Seagorath's head, King Crab's tail, Barabas' arms, and Hanzagrian's back.
- Izmael/Ezmael from Ultraman Nexus had the combined body parts of all the previous Space Beasts.
- Giga Chimera from 2008 Superior Ultraman 8 Brothers movie. Its heads are those of Goldras and Silvergon, its upper torso is Alien Hipporito's, its lower torso is Gesura, its legs are those of Gesura and Pandon, and its tails are Pandon's twin heads.
- The concept design was much more complex. It had Vakishim's head, tail, and arms; Astromons' horn and arms; Eleking's antenna and tail; Gomora's horns and tail; Red King's legs; Monsarger's body; Twin Tail's body; and the above-mentioned Tyrant's legs, arms, horn, neck, and body. It was scrapped due to Hybrid Over Kill Avoidance. See here.
- Perhaps the ultimate example is One-Winged Angel Beryudora from 2009's Mega Monster Battle: Ultra Galaxy Legends, a behemoth (it completely dwarfs the Ultramen) composed from the still-living bodies of every single monster from the franchise up to that point. Oh, and it was made with practical effects, so you're seeing a very well-made puppet.
- Five King from Ultraman Ginga S is the fused heads of Golza and Melba, torso of Golza and Super COV, Melba's wings and tail, Super COV's legs, Reicubas as a right arm, and Gan Q as its left arm.
- Zeppandon from Ultraman Orb is a hybrid of Zetton and Pandon, the final enemies of Ultraman and Ultraseven respectively.
- Ultraman Geed has three: Skull Gomora (hybrid of Red King and Gomora), Thunder Killer (hybrid of Eleking and Ace Killer), and Pedanium Zetton (hybrid of Zetton and King Joe). They are created by Fukuide in a similar fashion to how Riku becomes Ultraman Geed.
- Paragon prominently features a lion/eagle/lizard hybrid griffon on both its backglass and playfield.
- Dungeons & Dragons loves this trope:
- The Gorgimera, a chimera except goat head is replaced with a gorgon. Just to be clear, gorgon in this case is not a woman with snakes for hair (we call them medusas in D&D), but an iron-skinned bull with petrifying breath.
- The players can become this with some effort, for example, one can become a half-Celestial Minotaur Werebear Vampire Lich via templates added to your character. Note that this particular one is impossible, as an half-Celestial cannot become a vampire, and a vampire cannot become a lich.
- The monster sourcebooks contain lots of hybrid monsters, like the Drider, which is like a centaur but with a Dark Elf top half and giant spider bottom half.
- d20 uses "templates" which graft part of one monster type onto any existing one. This can be used to make half-dragon wolves or half-angel kobolds. Templates can even be stacked, to make stuff like half-fiendish half-troll half-elemental pseudonatural vampiric werecrocodile goblins.
- There was an essay exploring the possibility of a vampire werewolf,with one of the major points of contention being whether the undead nature of the vampiric template would override the lycanthrope's shapeshifting ability. Of course this requires the templates to be applied in the proper order, as lycanthropy is a disease and undead are immune to all disease, so a vampire cannot contract lycanthropy.
- 3.5 sourcebook Bastards and Bloodlines (from Green Ronin) contains over 30 different half-breeds, from the believable (Mergs [human/merfolk]) to the silly (elf/giant eagle, halfling/blink dog). They also provide the option of creating your own, if you find the options unappealing.
- Perhaps the least dangerous of all is the duckbunny. It's created by apprentice mages who want to practice making ridiculous hybrids without risk of being eaten by the result. (Obviously, Wizards of the Coast was having a little fun with the idea when they came up with this one.)
- The thessalhydra, thessalmera, thessalgorgon and thessaltrice are particularly bizarre; hybrids between the hydra, chimera, gorgon, and cockatrice (two of which are already Mix-and-Match Critters) and a reptilian, lamprey-like creature called a thessalmonster. Actual thessalmonsters don't appear in the game, though, because they've been hybridised out of existence.
- DeadLands: Hell On Earth has vampire werewolves in the main handbook.
- Exalted has a lot of detailed rules and suggestions for generating whatever sort of giant amalgam of monsters you want.
- Magic: The Gathering: It is fairly easy for such creatures to crop up, as the various creature types that define the nature of each creature card can be mixed and matched in any theoretical combination (indeed, doing such things is the only way to add adjectival modifiers to individual creature types, although the extra types are usually professions like Barbarian, Soldier, Wizard or suchlike). Specific examples include:
- Accursed Centaur and Returned Centaur are Zombie Centaurs, while Karador, Ghost Chieftain, is a Centaur Spirit.
- Gaea's Skyfolk are Elf Merfolk that can fly for some reason, despite neither parent species being able to do that.
- Razorfin Hunter, a Merfolk Goblin. It's notable that no-one in-universe actually knows where these things came from.
- Other mixed undead are common, like skeletal griffins, zombie dwarves, vampire dragons, zombie elves and merfolk... one of the most extreme has to be a zombie centaur aven (aven being bird people) from the Scourge block.
- Malfegor isn't the best, but he sure as hell qualifies, what with being a half-demon, half-dragon... thing.
- If all that didn't sound scary enough, there are zombie minotaurs! Part bull, part man, all undead!
- Warhammer has, among other things, Dragon Ogres) which, confusingly enough, are not related to normal Ogres at all), Skeleton Giants (which may or may not include any Giant bones — really they're just oversized bone golems), Zombie Dragons (Exactly What It Says on the Tin), Chaos Dwarf Bull Centaurs and Chaos-corrupted versions of just about anything. Chaos at least includes a kind of Hybrid Overkill Avoidance in that anything with too many mutations devolves into a shapeless Chaos Spawn.
- Warhammer 40,000 has the Soul Grinder, essentially a Cyborg Daemon.
- This happened rarely in the Old World of Darkness — it was more common in the early editions, but then the writers decided that such a thing was too gimpy. There were some exceptions, such as the Abominations (werecreatures who'd been Embraced, forced to live out a hollow and torturous existence as the natural world rejected them utterly) and the infamous case of Samuel Haight, the Kinfolk turned werewolf with vampiric Disciplines and Awakened magic (who eventually got killed and turned into an ashtray).
- Largely impossible in the New World of Darkness, where being one type of supernatural creature cuts off the chance of being another type. Werewolves are immune to the static effects of vampire blood because they're shapeshifters (though they can still be addicted to it...), mages are killed if you try to Embrace them, Prometheans don't retain any supernatural qualities of the body used to make them, and so forth. There are some examples, however. Magath are spirits that, in the dog-eat-dog-and-also-whatever-dogs-normally-eat world of spirits, have consumed a spirit that is not a part of their nature (e.g., a cat spirit eating a typewriter spirit), producing a hybrid that embodies both concepts and is quite mad as a result.
- Feng Shui has Abominations: all kind of demons and supernatural beasts or monsters turned into cyborgs by fascist Mad Scientists from THE FUTURE!. They even serialized the production of Jiangshi, the Chinese hopping vampires, calling the cyborg version "Bouncing Benjys." If you use your Arcanowave gear too much, you run the risk of becoming one of these things yourself!
- In the Yu-Gi-Oh! game, Fusion Monsters are usually like this, but not always. For example, every Fusion that involves Elemental Hero Wildheart looks like Wildheart wearing a version of the other monster's armor or costume, so the Trope fits. However, some Fusion Monsters don't fit the Trope at all. (Musician King is a good example. A Fusion of Witch of the Black Forest and Lady of Faith? What the...
- Monster High has the Freaky Fusion special, which introduces four hybrid characters, and the Fright-Mares line, which consist of dream-spawned centaurs who are crossed with the monster type of their dreamer.
- In 8-bit Theatre, Black Mage expresses dislike for this sort of monster. (For those who are confused as to why the whale vulture is a whale with robot legs, the vutlure part comes from a battlemech called a vulture.)
- In The Inexplicable Adventures of Bob!, Molly the Monster is a "genetic chimera thingie" combining the DNA of many different creatures, including human.
- Last Res0rt makes this the default form of the Celeste; literally, they're made up of all sorts of different species, to the point that there's no such thing as a "purebred" Celeste, and they seem capable of mating with any (sentient) species.
- George the Dragon has the offspring between the titular George and the Loch Ness monster. Plus a lobster, for no explainable reason.
- El Goonish Shive
- The Uryuom "eggs" that mix more or less any critters and produce viable offspring shapeshifting between parent species' forms. Uryuom is not necessarily a part of this. One of main characters is Human/squirrel/Uryuom/another-alien-creature combining forms at will.
strip name: Uryuom Sitcoms are Insane.William: The current known record for number of parents to a single child is twelve, and only nine of those were Uryuoms.
- Mr Verres and Mr Raven both have pet hedgecats, which appear to be normal cats apart from the hedgehog spines. Their origin has not yet been revealed.
- The Uryuom "eggs" that mix more or less any critters and produce viable offspring shapeshifting between parent species' forms. Uryuom is not necessarily a part of this. One of main characters is Human/squirrel/Uryuom/another-alien-creature combining forms at will.
- The Order of the Stick has Malack, the lizard person-vampire, and now Durkon, the dwarf-vampire. Also, Girard (or Girard's Gate fame) apparently had some dragon ancestry.
- Common in Fairy Dust. Any humanoid can breed with almost any other. Some particular cases happen:
- Incubae's traits are exclusively found on the Y chromosome. An incubus's daughter is not an incubus (or a succubus). The race can only reproduce with a female from another race. The typical incubus is such a genetic patchwork that it's hard to tell what his family tree looked like.
- Tiny elves hybrids are great elves, the genetic defect making them tiny, sickly, and obligatory cannibals being corrected by outsider blood.
- White Dark Life: Though most of Tori's related family(excluding Boar) are effectively this, she deserves special mention as her transformed state has the physical characteristics of a nekomata, but also possesses the power to raise the dead like a bakeneko.
- Monster Rancher, a popular take on the monster-raising genre, has this as the main monster differentiation. In any one game there'll be 20-25 base breeds. Main/Sub is the most common shorthand i.e. Golem/Golem for a Main Golem/Sub-breed Golem "purebreed." If you mix it with a Hare/Hare you might get a Hare/Golem or Golem/Hare.
- The Zerg and Protoss Hybrids are part of a major story arc in StarCraft. It started in the secret mission of Brood War with Zeratul finding them in cryo-suspension on a remote dark moon, and by StarCraft II it has been confirmed that not only are they spread throughout the Galaxy, but they are waking up and will bring forth the end of the Universe under the command of the Fallen One.
- World of Warcraft has cyborg demons, zombie giants, skeleton dragons, vampire elves, 10 feet tall zombie vikings and many more.
- Druids can shapeshift into a moonkin, a combination of the wisest (owl) and strongest (bear) animals.
- Doom has Mancubi, which is a demon with guns for hands and robot legs; Arachnotrons, which are giant brains with robotic spider bodies; and Cyberdemons, which have a rocket launcher for an arm, one robotic leg each, and wires for a midriff.
- Those aren't really hybrids, they're more like a demonic Hollywood Cyborg. Doom 3 did include a few, though. The Cherubs (half-infant-half-insect, and the Vagary (half-lady-half-spider).
- Whilst the Castlevania series uses a lot of mythological monsters, it also creates its own, like a monster which is half zombie skull half butterfly. And half naked chick and half dinosaur.
- Nero Chaos in Tsukihime. Technically, he started out as a human but now shares his identity with 665 other creatures, so the actual humanity he has left is essentially negligible. Capable of some degree of shape shifting between forms and also something of an ultimate killing form that isn't described very well. His body includes dogs, tigers, at least one doorshark, bears, dragons, unicorns, a blue crow, one vampire, some jaguars, giant crab monsters, stags, wolves and who knows what else.
- Add a deer to the bunch. Or that was for his cat counter-part, Neco-Arc Chaos.
- Touhou has Keine, a were-hakutaku. Umm... a hakutaku is something like a giant lion with extra eyes and horns. In practice, this really means that on nights of the full moon, Keine grows horns, a tail, changes in power and hair color, and gains new superpowers. Because people don't really know what a hakutaku, much less a were-hakutaku, is, fan jokes tend towards portraying her as a cow.
- Goosebumps: Escape from Horrorland has terrifying crab-slug hybrids lurking within the labyrinths found inside the park's trash cans. It's never explained what exactly they are or how they came to be; even the name of their species is only found in the manual.
- Belial, the protagonist of Painkiller Overdose, was fathered by an angel and born from a demon, making him a half-angel half-demon. Which he will constantly remind you of just in case you happen to forget.
- A recurring monster in the Suikoden series is the Zombie Unicorn.
- Final Fantasy VI had the Skull Dragon, a skeleton dragon who is an optional boss that you have to defeat to get the Crusader magicite and the powerful Meltdown spell.
- Final Fantasy XII and Vagrant Story also had skeletal dragons, and the latter threw undead variants of ogres and minotaurs into the mix as well.
- Final Fantasy XIII gives us, at the very least, cyborg wolves and Behemoths (with Tron lines, no less!); however, as well as "recognisable" hybrids, the game also treats us to a whole menagerie of weird and wonderful mash-up monsters that defy description. In particular, this Troper isn't entirely sure what certain Annihilators like the Proudclad are supposed to be, but it can't be pleasant.
- The Alien in Mortal Kombat X is a Xenomorph/Tarkatan hybrid, possessing the strengths of the Xenomorph (acidic blood, prehensile barbed tail, durable chitinous hide, deadly second jaw) with the physical build and arm-blades of a Tarkatan.
- In Shin Megami Tensei: Strange Journey, the crew of the Red Sprite find a demon in Mitra's palace being tortured by the other demons. An examination reveals it's made with equal parts demon and human DNA. Jiminez, showing a softer side for the first time in the game, saves its life by adding it to his Demonica and names it "Bugaboo" (the only word it can say).
- RuneScape has Newtroosts, Unicows, Spidines, Swordchicks, Jubsters and Frogeels. You make them yourself, player.
- Nightstalkers in Fallout: New Vegas are a cross between a coyote and a rattlesnake. They look about as strange as you'd expect.
- AdventureQuest has Fur Against Fang as a major theme in the Darkovia region. There are also a few Werepyres running around. And then someone had the bright idea to take a Werepyre and add some Dragon to the mix, creating Nightbane the Dracopyre. His bite also infuses ordinary Vampires and Werewolves with some draconic traits.
- The Sanctuary Guardian from Dark Souls is a white lion with ram horns, four bird wings and a scorpion tail. In other words, almost a textbook manticore.
- Black Kyurem and White Kyurem from Pokémon Black 2 and White 2, the result of combining Kyurem with either Zekrom or Reshiram, respectively. However, Unovan legend states that the three were originally one being, so this might be a case of the creature being incomplete rather than a hybrid. (And no, you cannot combine all three if you own all three Pokemon.)
- Many of the husks in Mass Effect are this as the Reapers like to experiment. Scions are basically three organics mashed together with a big gun, Cannibals are batarians crossed with humans and the Brutes are a krogan crossed with a turian. The last is probably the worst as those two species aren't even biochemically compatible.
- In Borderlands 2, one quest chain for Dr. Zed has you collect body parts from rakk, skags, and spiderants. The former two are made into flying skags called "skrakks" and the latter is combined with parts from a psycho to make a "spycho". Hilariously, when you go on the third quest, Zed tells you that it's technically your fault since you agreed to get the parts for him.
- The entire mechanic of Jade Cocoon revolved around capturing Mons and fusing them to try and pass on strong traits, spells, and techniques while weeding out the weak and less desirable ones. Then of course you can fuse your fused monsters again and again and again as much as you like.
- Xenoblade Chronicles X: The Lifehold generates a group of creatures known as chimerae as a defense mechanism. Unfortunately, it's also malfunctioning, so what it creates are twisted amalgamations of multiple Earth creatures, resulting in... things that resemble lizards with three tails, a triple-split mouth, eyes in their shoulders, and other extremely creepy attributes. And that's not even getting into what it does to Lao and Luxaar...
- Equestrian Legends has the Kirin. Half pony, half dragon. On a larger note, it's implied that dragons really sleep around and use life-altering magic to make sure the babies survive.
- "No One Comes to Lupusville", a Real Ghostbusters episode with a Fur Against Fang theme, asks the question, "what happens when werewolves and vampires bite each other?" They wisely don't stick around to find out.
- In The Grim Adventures of Billy & Mandy, nerdy Irwin turns out to be half-mummy and one-quarter vampire.
- He also gets transformed into a werewolf in one episode, although it's later reverted.
- And he really shows off his talents in the Underfist Halloween special.
- In one episode of Captain Planet and the Planeteers ("Planeteers Under Glass"), there is one futuristic flying cyborg-demon among the Mix-and-Match Critters that only appears in the virtual planet... for a short while anyway, all while the Apocalypse Class is getting spiked up to Class 6!
- Marceline in Adventure Time is revealed to be a demon/human hybrid who then at some stage was turned into a vampire. It's left unclear which of her powers come from which source.
- As it turns out most of her powers are technically from the vampire side as revealed in the Vamps mini-arc. Though she doesn't have to be a vampire to have these powers; she gains them through her sole demon power, soul sucking. Absorbing the essence of vampires also absorbed their powers; she only became a vampire due to a survival gambit by the Vampire King, who ironically is a hybrid monster himself.