- Actor Allusion: "David, isn't there a housewife that's desperate for you somewhere?"
- Actor-Shared Background: Asian Blair was of Japanese and European ancestry, just like her first actress, Mia Korf.
- Cast Incest: Inverted. Real-life siblings Kristen and Eddie Alderson play unrelated characters. A few years back, a storyline involved Eddie's Matthew having a crush on Kristen's Starr. The boy had to pretend to have a crush on his sister. Gross.
- The Cast Showoff: Several actors on One Life to Live. For instance, the original actor who played Jessica, Erin Torpey, has a nice singing voice, so they had Jessica in a band at one point, and also had her sing on a few other occasions. Evangeline Williamson got to sing a lot in the show, because her actress Renee Goldsbury is a real life singer/song writer, and was on a Broadway musical. And Blair Cramer, is also shown singing on a number of occasions, because Kassie DePaiva is a singer and has albums out.
- The Character Died with Him: Phil Carey (Asa Buchanan), John Perry (see below).
- Fake American: Nathan Fillion (Joey Buchanan) is Canadian.
- Subverted with Susan Haskell (Marty Saybrooke), who is Canadian-American—she was born in Toronto, but both of her parents are US citizens, automatically granting her US citizenship as well.
- Fake Nationality: German Thorsten Kaye as Irishman Patrick Thornhart.
- The Other Darrin: Lampshaded hilariously during the Vicker Man premiere - Blair is asked how she feels about being played by an Asian-American actress in the movie; cue to the cast credits, where the actress credited as Blair is Mia Korf (the Asian-American actress who originated the role of Blair Cramer).
- 2011's Two Todds storyline thrives off of this.
- Real-Life Relative: Scott and his mother Lisa Evans play Oliver and Barbara Fish.
- Reality Subtext / Real Life Writes the Plot: NYPD officer John Perry had a recurring role as a police officer. He was killed in the 9/11 attack. To honor him, the show had his character die in precisely the same manner (though it was tweaked to say that Perry had been visiting New York that day, as the show is set in Pennsylvania). The first anniversary of the attacks was subsequently commemorated both on and off-screen when Commissioner Bo Buchanan was seen gazing at John's photo and sadly declaring, "I can't believe it's been a year" (it is highly likely that Robert Woods' Real Life emotions were on display).
- Romance on the Set: Susan Haskell & Thorsten Kaye, who played Marty Saybrook & Patrick Thornhart, married not long after leaving the series.
Trivia / One Life to Live