Trivia tropes:
- All-Star Cast: The film concentrated as many French comedic actors and stand-up comedians of the early 2000s as it possibly could along with the main cast.
- Creator Recovery: Gérard Darmon's role in the film allowed him to get out of a severe depression.
- Deleted Role: A then-unknown Omar Sy had a small role as an Egyptian painter◊ in a Deleted Scene.
- Descended Creator: Alain Chabat (Julius Caesar) is also the director and screenwriter.
- Disowned Adaptation: Albert Uderzo didn't like the film. He found it too mired in the "Canal Spirit" ("L'Esprit Canal", the brand of humor of the French TV channel Canal+, of which Alain Chabat was of one the patron saints) and way too far removed from the spirit of his comic books.
- Fake Nationality:
- Monica Bellucci (Italian) plays Cleopatra (Egyptian of Greek Macedonian descent).
- None of the Egyptian characters is played by an actual Egyptian.
- Multiple Languages, Same Voice Actor: Monica Bellucci, who portrayed Cleopatra, dubbed herself in the Italian dub of the movie.
- The Other Darrin: Some actors from Asterix & Obelix Take on Caesar didn't return.
- Gottfried John portrayed Julius Caesar in the first film. He was replaced here by Alain Chabat, who was also the director.
- Getafix's role also went from Claude Piéplu to Claude Rich.
- Those Two Actors: Alain Chabat and Gérard Darmon formed a memorable dancing duo in La Cité de la peur before this film.
- Throw It In!: Edouard Baer improvised Otis's famous "There's no good nor bad situations..." speech.
Other trivia
- It was a smash hit in France upon release, currently the 11th biggest theatrical success there with 14,5 million cinema admissions.