The comic follows a group of artists, gamers, nerds and otherwise downright insane roomates in the city of Generic City. Among them are Agent, the immortal Butt Monkey of the group; Jack, the British Deadpan Snarker; Aakashi and Wraith, two lovers with varying enthusiasm; and more. The series often takes the form of a Slice of Life, though has plenty of Video Game humor, and includes arcs where the Reliefers are pitted against a foe, like Kyle Marks and Billy Blonka.
Comic Relief provides examples of:
- Ascended to a Higher Plane of Existence: Agent's description of Orange's CEO, Matt Orbb. A literal orb in a strange ethereal plane where his subordinates can still meet him.Employee: Sir, our stocks went up fifteen percent!
Matt Orbb: AS I EXPECTED. I AM SO TWEETING THIS, MAN.
- Bland-Name Product: Orange phones, for example.
- Butt-Monkey: Agent, and how. Being immortal, he takes a lot of punishment. The first strip has him get a boxing glove to the gut. The second has him being SHOT.
- Captain Ersatz: Blonka is a Composite Character of both Gene Wilder and Johnny Depp's portrayals of Willy Wonka, according to Word of God, and at least as far as clothing goes. He possesses the purple suit of Wilder and the goggles of Depp. Personality-wise, he's a total Jerkass.
- Cat Girl: Agent has become a downplayed version of one on at least two occasions. There's also Tabby, who's a cat boy, and formerly Farniro and Tail.
- The Cameo: Both the Judge and the Swedish Chef appear in the Baking arc, as celebrity judges.
- Chuck Cunningham Syndrome: Insheba and Jonny T simply disappeared in later strips. Word of God claims that the people they're based off of have disappeared from the author's contact, thus he gave them the ax.
- City of Adventure: Considering this is a city where mad science goes on frequently, anthros are perfectly socially acceptable, and chaos is inevitable, Generic City Counts.
- Also a City of Weirdos, seeing as how the above happens often.
- Corrupt Corporate Executive: Billy Blonka. His business practices involve intimidation of the competition by having his Voompa-Boompas punch them in the face with brass knuckles. Agent found this out the hard way.
- Deadpan Snarker: If Jack isn't immediately ditching the group, he's most likely commenting on the idiocy of the scheme he's involved with.
- The Ditz: Agent frequently bounces between this, Psychopathic Manchild, and holder of the Genius Ball. Sometimes in the same strip.
- One example is him suddenly realizing he only possesses four fingers. Apparently it took him 3000 years to realize it.
- Genki Girl: Aakashi occasionally crosses into this, when properly motivated. Her boyfriend, Wraith, is much calmer in comparison.
- Failed a Spot Check: When breaking into Blonka's factory, Agent tries climbing up onto a low roof for a full minute. Instead of taking an easier route.Jack: "Agent. There is an UNLOCKED DOOR."
- It Amused Me: Jack's explanation to Wraith as to why he didn't tell Agent he turned into a snowman in August.Wraith: "And you didn't tell him because...?Jack: "It was funny."
- Mad Scientist: Zero.
- Police are Useless: Fights occur, things are set on fire, and yet the local police don't appear, ever.
- Put on a Bus: Happens to Farniro and Tail, who peacefully moved out of the house. And were quickly replaced.
- Pyro Maniac: Agent. He has both torched a movie theater and Kyle Marks' car so far.
- Really 700 Years Old: Word Of God claims that Agent is roughly 3000 years old, yet still looks like a young 20-ish year old man.
- Screw This, I'm Out of Here!: Jack performs this a lot, such as when Agent spontaneously became a chibi Cat Girl:Jack: "Screw this. I'm going to the pub, guys! Later."
- They Killed Kenny Again: Agent is expressly immortal, which is why he can be shot, stabbed, and outright explode, yet arrive in perfect condition the next day. The other characters know this and abuse it.
- Unfazed Everyman: Over half the cast. When your roommates are an immortal, a catboy, a mad scientist, and a telekinetic rabbit, this is bound to happen.