Affably Evil: Barry the Chopper. He's fine with joking around with his name, and answering Ed's question; tying Ed up is as hostile to him as he gets. He even asks if they still can't be friends, despite wanting to chop him up. Predictably, they find common ground, as a butcher and nightmare fetishist, respectively, which they have a heart-to-heart talk about.
Frankly, he's nicer to Ed than the military. Well, except for the part where he stabs Ed. He's still a serial killer, after all.
Lampshaded by Ed, after he and Winry are freed.
"Nice bloke, though, if you look past all the mutilation, I mean."
As of episode 11, possibly Scar, who seems to use the word "Friends" in place of "Victim".
The Caligula: King Bradley. Creates a mandatory national holiday specifically to make fun of Mexicans, and later grants Edward an alchemy license just for sitting in a chair. He also decreed the death penalty for anyone wearing green in what is widely remembered as the worst St. Patrick's Day ever and likes to spend Alchemist's Christmas stabbing people if they don't enjoy themselves... or even if theydo.
Cloud Cuckoolander: Many, and in tiers, no less. Bradley sits at the top, followed closely by Maes Hughes and Barry. Roy Mustang is a few rungs beneath, and Ed only a little ways below that. Only Riza and Al qualify as sane.
As of Episode 7, Ed as admitted that the grotesque fascinates him. Al outright calls him a nightmare fetishist.
Only Sane Man: Both Al and Riza have found they relate to each other.
Occasionally Edward, when he's not threatening to eat Father Cornello or going in psychotic rants.
Roy Mustang - at least, in comparison to Fuhrer Bradley and Maes Hughes.
Essentially, it's a Cloudcuckooland with everyone's sanity varying on different subjects and in comparison to each other. Best exemplified in episode 11, when Roy and Ed are sane to Bradley, Ed is sane to Roy when his anger isn't in the way, Hues is the sane man to their fight (while also shipping them), and Al's sanity flies out the window once he gets his hands on a cat. And Riza's sane to everyone.
Riza and Marcoh are so far the only characters who are not clearly insane.
Police Are Useless: Oh yes. Not only do they confuse a 15-year-old with an adult woman twice his height, but they're utterly baffled by the use of magic. In a setting where said magic is basically public knowledge. What.
Shout-Out: Al's Johnny Yong Bosch voice and his response - "I don't like Johnny Yong Bosch" - are both references to one of the anniversary videos done by LittleKuriboh. In the video, LK had a puppet that spoke in that same voice - claiming to be JYB - and he would always say "I don't like [thing]".
In Episode 7, the final paragraph in King Bradley's long explanation of Edward's title is the lyrics to the theme song of The Fresh Prince of Bel-Air. note "...this is the story all about h..." and "...to take a m..." can be seen.
In Episode 10, when the Elric Brothers first encountered the Tringham Brothers, Ed and Russel used the dialogue from Sonic and Shadow the Hedgehogs of Sonic Adventure 2, much to Al and Flecter's annoyance.
Tempting Fate: In episode 3, after Winry tells the Elric brothers that her parents are dead. Ed responds that something like that will never happen to their mother (while saying ever a few times). 3 seconds later, she's hit by lazy malaria and dies.
Title Drop: "Nullmetal Alchemist" becomes Ed's official title.
Roy: A Nullmetal Alchemist, yes! What do you think?
Ed: That... doesn't make any sense.
Roy: Ha ha! Of course it doesn't! These things aren't meant to. "Ment", get it?