Izuka, from Path of Radiance and Radiant Dawn is pretty much Fire Emblem's version of Josef Mengele. He transformed hundreds of Laguz into Feral Ones, crazed Laguz forced into their beast forms, and he considers it all in the name of science. In the second game, he tries to transform one of the Laguz on his side into a Feral One; luckily, you're able to prevent him from doing this. And that's before you learn that he chose Pelleas to be king of Daein so that the senators could force him into a blood contract. This forces Pelleas to either do as the senators say, or watch as his kingdom dies. He also used the Feral One-creating elixir to turn Elincia's uncle, Renning, into the insane Bertram (showing that it also works on Beorc, albeit differently than with Laguz). Fortunately, the Heron Laguz are able to cure him. It is immensely satisfying when you finally get to kill the slimeball.
Let's not forget that Izuka also lied to everyone about Pelleas being Ashnard's son and heir. Including Almedha, the mother of Ashnard's child, who was almost driven mad because her child was taken away and she was too emotionally unstable to stop and think about whether or not the boy Izuka introduced as her son was actually the right person.
Also from Radiant Dawn, we have Lekain, who will do anything to move up on the social ladder. ANYTHING. Even directly causing the genocide of the most peaceful race on the planet by blaming them for the assassination of his country's empress. And did we mention he was the one who actually killed her?
Actually, I doubt he did it on his own, he probably just had Begnion soldiers under the Senate's control or maybe just a hired assasin do it. But let's recite everything ELSE that Magnificent Bastard did: he made Sanaki and Sephiran the Empress and Imperial Advisor of Begnion so that no one would get wise to the Senate's actions or to the fact that the REAL Apostolic heir was killed along with Misaha. (It turns out Micaiah survived somehow.) THEN, he puts Daein under Jarod and Numida's mercy, where they suffer the fate of Eastern Europe by the Soviet Union during the Cold War. He THEN starts the war with the Laguz Alliance to expand his influence and exterminate ALL laguz, along with Sanaki and Sephiran, and framing the remaining herons YET AGAIN. And EVEN when everything is stone, he orders a mob of zealots to kill you under the impression that you are Satan's minions!WHAT THE F**K!??!?!
Don't forget Ashnard. He's not called the "Mad King" for nothing. This guy became the King of Daein by getting his father to sign a blood pact, and then invoking it, killing everyone else who was in his way to the throne, not to mention countless other innocent people. He then proceeded to kill his own father, therefore becoming king. After finding out about the dark god, or rather, Yune, who really isn't evil, sealed in Lehran's Medallion, he decides to release it for the lulz. This requires a war that spans the whole continent, so he decides to begin by invading the next country over. He also, after finding out that his own son Soren was unable to transform into a dragon like the child's mother Almedha used to be able to, decides to hold him captive to get ahold of the kid's uncle, the oldest son of the king of Goldoa. He then proceeds to warp Rajaion's body and turn him into something resembling a wyvern, and then use him as a mount. He laughs at everything. He wasn't even aware of the existence of Jill's father, Shiharam, who was a pretty high-ranking Daein general. He doesn't care at all about anyone except for himself, and he'll do anything, ANYTHING, to get power. His ideal world, the one that he wishes to create, is one where the only thing that matters is power. And did I mention that this is the guy that the aforementioned Izuka used to work for? He may not be quite as loathsome as some of the others on this page, but I think he still qualifies as a Complete Monster.
Previously, in Blazing Sword, there's Sonia. Manipulating a small group of Robin-Hood-like warriors to the dark side and abusing button-cute Nino are evil acts. But mercilously slaughtering the leader of said band after laughing at him for believing she truly loved him, trying to get one of her underlings to kill Nino after another empty promise of love and affection, and, right before her final attempt to kill her, revealing that she murdered Nino's entire family and just kept her around, pretending to be her mother all her life are acts that any gamer with a scrap of heart tissue railed as unforgivable.
Potentially even worse is Ephidel, certified Evil Chancellor and essentially walking Diabolus ex Machina who has a tendency to ruin anything resembling plot resolution by stabbing people. The old Marquess with essential information? Ephidel stabs him. Lyn's grandfather, who you spent her entire campaign trying to save? Ephidel stabs him. Not to mention Leila, the Ostian spy and Matthew's girlfriend, who looks set to join your party - Ephidel calls on Jaffar, has her killed, and then orders Jaffar to leave her body in a position to make her look like she's still alive to mock the party. When the party confronts Ephidel over the issue, he proceeds to mock them, asking if "the gift" he left them was "to [their] liking". Sonia at least gets one small moment of pity in her final scene, which reveals she was just a delusional Tomato in the Mirror the whole time; Ephidel knows exactly what he is and, judging by the extremely irritating smug grin he perpetually wears, revels in it. His death is among the most satisfying moments in the whole game... and you don't even get to do it.
Earlier than all of them, we had Lundgren, Lyn's great-uncle. He is willing to send assasins after Lyn, poison his own brother Hausen just for a throne, and way too happy to mock his brother at the prospect of his granddaughter's death. Not only that - he spreads lies about Lyn being an imposter and Kent and Sain traitors, forcing the latter two to fight and kill their own friends and colleagues in battle due to a misunderstanding; and later, he blackmails the loyal and honourable General Eagler into fighting against his beliefs by holding someone close to Eagler hostage. Granted, he does believe, on some level, that Lyn's Sacaen heritage makes her unfit to inherit, but his own hunger for power and lack of loyalty (lampshaded by Matthew, stating "we can expect him on Ostia's doorstep before long"), coupled with his callous disregard for casualties even among his loyalists, makes him one of the game's most despicable individuals.
Two other very human monsters are Jerme and Pascal, former members of the Four Fangs. First, a bit of backstory: the Four Fangs are the four best killers in the assassination brotherhood, the Black Fang. Despite this grim job description, the four current members are quite honorable (the worst of them is Ursula, Sonia's Number Two, but that's due to foolish blind loyalty to her mistress rather than actual evil). These two, who have been removed from the group, are anything but. Jerme is an utterly psychotic assassin who enjoys slicing people into (apparently literal) ribbons of flesh and then feeling the result. Pascal's even worse. His Establishing Character Moment is when he tries an I Have You Now, My Pretty...on Sonia. We also receive an anecdote about him, then a Count, inviting the entire population of his village to a banquet and then killing them all. Note that it's entirely possible to go through the game without encountering either of these characters, so whether you want to dish out some karma or simply get as far away from them as possible is largely up to you.
King Desmond of Bern should not be forgotten here. He hates his true son simply because he is unhappy in his political marriage with the boy's mother. We find out that, between the events of Fire Emblem 7 and Fire Emblem 6 (which was released first but takes place several decades later chronologically), his terrible hatred came to a head when he attempted to murder his own son simply to keep him from succeeding him one day. And it wasn't the first time. Faking his death and funeral, his son is able to kill him when Desmond comes close to view the open casket. The son then becomes king and tries to rule the world, having been convinced that, without a dictator, humanity can never exist peacefully.
And previously again, in Genealogy of Holy War, we have Queen Hilda, the power hungry queen of Freege. As you gather information from village to village, you learn that she wholeheartedly supports the movement of sacrificing kids to an evil god and did it For the Evulz. Later on, it is revealed that she is very much responsible for the death of one of the first generation characters, Tiltyu, by abusing her and her daughter Tinny (who is a 2nd generation character), again For the Evulz (other 'traitor' reasons for her is just side things), to the point that she was reduced into a shell of her former cheery personality and died with it. And Hilda takes extreme pride on it and gloats about it in front of her children.
Hilda is actually so evil that she even comes up as an abusive bitch when Tiltyu and her kids are not there for her to abuse. Yeah, if Tiltyu dies child-less, her and Blume's little sister Ethnia will replace her as Hilda's punching bags, alongside her children, Amid and Linda (replacements for Arthur and Tinny). And the same goes for her daughter, Dark Magical Girl Ishtar, who may not have been physically abused as the others but still was manipulated by her Evil Matriarch mom because of her love for Yurius, which Hilda saw as a chance to gain even more power than she already had.
But let's not have the real CM of the game off the hook, huh? Manfloy the Dark Priest and archbishop of the Loputo Sect is the rare mix of CM and Magnificent Bastard, as he's extremely effective in his evil deeds...
First Generation: He manipulated various rulers and dukes, causing the war against Isaac by using Duke Reptor of Freege to assassinate Ira's father, King Mananan, while also manipulating King Chagall into killing his father and sending his envoy, Sandima, to stir up trouble in Verdane. During this time, he worked primarily with Alvis, whom he was blackmailing with the knowledge of Alvis's Loputo blood, in addition to his Fala heritage, thus poisoning him with hatred and envy. Later, he kidnaps and brainwashes Sigurd's wife, Diadora (and in one of the mangas, he outright mind rapes her and laughs about it), then manipulated her and the emotionally-weakened Alvis so they'd marry and have children who could be used as Loputo vessels. And as the cherry on top, he killed Levin of Silesia with his own hands in the Battle of Barhera (with Holsety becoming a Dragon Ex Machina to let him escape death).
Second Generation: A while before it started, he gave Prince Yurius the Loputo tome, causing him to become the vessel for the Dark God and kill his mother Diadora while attempting to kill his twin sister Yuria, shaping him into the horrible rival we'd meet later, and also attacked his pregnant daughter and his son-in-law purely because they broke his Parental Marriage Veto, killing him and driving her into insanity, which would cause his soon-to-be granddaughter Sara to be pissed off at him forever. And after all of that? He organized and helped commit the horrible child hunts already mentioned, and later kidnapped Yuria (who had been taken in by Levin, and later by Celice's army) and brainwashed her so that she'd become his and Yurius's Apocalypse Maiden. Go. To. HELL. Manfloy.
Valter from The Sacred Stones, a Wyvern Rider General who, after touching a cursed lance, had his bloodlust multiplied tenfold. He was originally kicked out of the Grado army for massacring even retreating enemy soldiers, even when ordered not to. When he's brought back, the only reason he doesn't capture Eirika and Seth immediately at the start of the game is so he can "savour the hunt ... and the kill" (his exact words). Later, he toys with Selena's emotions, telling her Emperor Vigarde is doubting her loyalty and ensuring that she dies fighting Ephraim. When his more honourable foil Glen begins to doubt the Emperor, Valter not only murders him, tricks his little brother Cormag into believing Eirika is responsible, which may lead to his death if you don't recruit him with either Eirika, Duessel, or Tana. To top that all off, he's a Giggling Villain who delights at the thought of capturing Eirika and Ephraim - after a long-winded chase - because he enjoys tormenting, taunting, and holding back. Even Riev states that Valter doesn't care about rules and morality, simply doing what he wants. His death is honestly one of the most satisfying in the game ( especially if you kill him with Cormag on Eirika's route), as his dying quote implies that he died in extreme pain.
Riev, a former bishop who, for no discernable reason, began to worship the Demon King. He leads/raises the Demon King's demonic armies to murder people, including raising a ship for them to use in sinking any boats on the water - just for his amusement. But when he stands by as the Demon King kills Myrhh's father Morva and raises him as a DracoZombie to fight his own daughter - perhaps even committing the deed himself - it becomes very clear how much you want him to die. Unfortunately, he dies crowing in triumph and believing the Demon King to have succeeded in resurrecting himself. Fortunately, he's wrong, as you manage to trap the Demon King's soul in the last Sacred Stone and destroy his body for good, ensuring he can never return. Phew!
Lang from the third game is one of the earliest examples. It's mentioned in the first game that he was a noble of Akaneia who betrayed his nation to Medeus and stole wealth from the poor, then went back to Akaneia once they start winning again. He is then made overseer of the defeated Grust, replacing Lorenz. It's mentioned, in the most kid friendly way possible, that he steals wealth from the poor, kills boys over ten], rapes and kills girls over ten, and kills entire villages if one person from there rebels, a technique the Schwarze Rosen will later pick up. When you attack him, Lang says that he was forced to do this by his boss, asking for mercy, but it is simply a trick to get the first attack in. Even Medeus and Gharnef have vaguely defined backstories on why they're bad; Lang is simply pure evil with no explanation. This guy is so over the top that he basically exists to make Marth realize that there's something wrong with Akaneia and rebel. It's vaguely implied that his actions were done to provoke Marth into conflict, making him look like a traitor.
Let's not get Gharnef off the hook, though. He turned evil and later killed Linde's dad, Miloah, solely because their master gave him the Aura spellbook instead of Gharnef himself, led the attack on Altea that killed King Cornelius to grab the Falchion and kidnap Elice, brainwashed Tiki into attacking Marth, and manipulated Hardin and corrupted him via the Darksphere, leading to four innocent girls (Elice, Nyna, Rena, and Maria) to be captured and offered as potential sacrifices for Medeus's resurrection. Worse, this also causes a huge war that turns the continent to hell and ruins the lives of many. And in the new games, he brainwashed the caretaker of a destroyed orphanage, Eremiya, to make her the horrible Tyke Bomb training bitch we met and fought. And once she lost against Marth's group, he restored her memories...purely to mock her as she died in despair! What The HELL, Gharnef.