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Anime & Manga
- In Kakurenbo, five demons hunt the group of children through a maze-like Ghost City in a twisted game of Hide and Seek until only one child is left. Four are straightforwardly monsterous in appearance and methods of hunting; their leader, the fifth, is far more subtle and horrifying.
- In Inaba of the Moon and Inaba of the Earth, one of Touhou's manga stories, one chapter has Reisen and Tewi getting lost in the basement of the Scarlet Devil Mansion, which is where the mentally unstable, highly dangerous Flandre happens to be locked up.
- One of André Franquin's Idées Noires comics is about a prisoner sent to a maze that turns out to be a planetoid. In a sequel comic, penitentiary officials appear in an helicopter, tell the perp that his sentence has been worsened, and proceed to airdrop a live leopard into the labyrinth.
- Mazeworld: At the center of the Death Trap-filled maze is the Doomster, a monster which adapts itself to the fears of the person who has managed to venture that far.
- The mysterious beast in House of Leaves stalks the explorers of the house, which quickly reveals itself to be an Eldritch Location that twists and changes around them. What the beast is is left ambiguous, with various theories in and out of universe calling it a (or maybe the) minotaur, a personification of the house, or an Animalistic Abomination.
- Used a couple of times in the Harry Potter series:
- Harry Potter and the Chamber of Secrets has the Basilisk which resides within the titular chamber beneath the castle.
- In Harry Potter and the Goblet of Fire, during the Third Task of the Triwizard Tournament, the Champions have to enter a magical maze with several dangerous beasts in it, including a Giant Spider, a Riddling Sphinx and a Blast-Ended-Skrewt. The film adaptation leaves the monsters out, and instead makes the maze hedge attack the champions with its branches and roots.
- The Beast of London in Neverwhere is an archetypal mythical creature comparable to the alligators in the sewers of New York. It takes the form of a gigantic boar and prowls a maze far, far, beneath the city where it also incidentally guards the prison of the angel Islington.
- In the Watership Down story "The Story of the Comical Field," El-Ahrairah goes into a maze that turns out to be home to an undescribed horror.
- Doctor Who:
- "The Horns of Nimon" features an alien monster that lives in a maze where the walls shift around to prevent anyone escaping. The Nimon looks something like a bull-headed man, and is explicitly compared to the Minotaur.
- "The God Complex" features an alien Minotaur that lives in a hotel-like maze that abducts those who have different faiths and beliefs, it's endless rooms containing the greatest fear of its prisoners to break that faith, reducing the prisoner to uttering "Praise him", allowing the Minotaur to feed on them.
- In "Heaven Sent", the Doctor finds himself in a revolving castle with a mysterious creature that slowly chases him, only pausing when the Doctor confesses one of his secrets. The Doctor eventually makes it out by breaking through a wall of solid diamond that took him over a billion years to break through, having to constantly renew himself every time the monster caught him. After he escapes, it's revealed to have been his confession dial.
Myths & Religion
- Two Dungeons & Dragons modules have a minotaur with its lair inside a maze.
- B2 Keep on the Borderlands. The minotaur has a cave complex inside the Caves of Chaos. Its caves have a spell on them that causes intruders to lose all sense of direction.
- S4 The Lost Caverns of Tsojcanth. Somewhere in the Caverns is a teleportation trap that sends victims to other planes of existence. One possible destination is a giant labyrinth with two minotaurs riding bulls. They will hunt down and kill anyone inside the maze.
- In Batman: Arkham Asylum, in order to obtain the spores needed to make an antidote for Joker's Titan formula, Batman has to traverse the sewers underneath Arkham Island, while being pursued by Killer Croc.
- King's Quest VI: Heir Today, Gone Tomorrow has a literal Minotaur inside a maze (it's even on the box art) that the Winged Ones chuck the protagonist into if he's tenacious and foolish enough to visit their realm. In theory he's trying to save their princess, but mainly it's their attempt to get rid of him. However, if he manages to save the girl and get out alive, they owe him a favor.
- One level of Sly Cooper and the Thievius Raccoonus appropriate titled "Lair of the Beast" involved Sly sneaking through a swamp where one of the Fiendish Five was housing a giant serpent, with Sly needing to keep a head of it once it appeared onscreen.
- The Mole Men from Vanish serve as this.
- In Hunt the Wumpus, the player hunts the titular monster (which can be distinguished only by its stench) within a cave whose twenty rooms are connected like the vertices of a dodecahedron.
- The Legend of Zelda series is made up of these, with the player character having to traverse labyrinth-like dungeons to find one of the Big Bad's lead monsters.
- 3-D Monster Maze on the Sinclair ZX81 deposits the first-person player in a labyrinth with a Tyrannosaurus Rex. The objective: escape before you become Rex's lunch.
- Monsters wander five of the six mazes of Escape From The Mindmaster. They're just trying to find their way out just like you, but if you bump into one, you lose a chance.
- Oglaf (generally NSFW, though not this one): In the comic "The Labyrinth", a royal advisor is obsessed with building the King a labyrinth, which the King just gets annoyed with, citing he has no reason to need one. Then a guard walks in to inform the King that his wife has birthed a monster, much to the advisor's delight.