In Batman and Sons, Superman relates all the nasty things Batman has done to him ("always reminding me I'm not human...sticking Kryptonite in my locker after painting it with lead...calling me a naive Farm Boy who's had his head under too many cows' behinds to know any better"), passing it off as him being "such a kidder."
Project 0: to quote the trope description this is implied to have happened to 'the kid who can warp the fabric of reality and just wants to be left alone.' Instead of fighting back he just decides he wants to go home instead.
The first episode of minus, and it happens a few times later. Fortunately, it depends on her mood whether she'll retaliate or go do something else. Later on other kids start to realize that it's cool to have someone who can warp the fabric of reality as a friend. Unfortunately, asking her for a favor can be just as bad.
From Spinnerette, in this strip Alexis, AKA Evil Spinnerette, is being taunted by some Alpha Bitches ... despite the fact that she's a Drider, normal human from waist up and giant spider from the waist down (and has 6 human eyes in 2 columns of 3, or 3 rows of 2). Not to mention the fact that it took a super hero to capture and subdue her in the first place.
Subverted. They work for her, and she set it up so that Good Spinnerette would feel sorry for her and believe her claims that she wanted to turn back human.
A plot-arc has the human inhabitants of a village relentlessly bullying both a female Orcish innkeeper and her young daughter, who is able to bite through chunks of wood and drive a large metal spike into a board with one hand. After being kidnapped by a raiding party, she returns to wreak bloody vengeance on all those who slighted her.
Jack, who made an accidental trip into Zimmy's world, viciously teases Kat (whose parents are teachers) and Annie (who is friends with two godlike Trickster Mentors as well as most of the staff). Earlier he edged into Too Dumb to Live territory when he threatened Annie in front of one of the said trickster mentors, who was a giant wolf at the time (he casually brushed it off. Once you've been to Zimmy's world nothing in this one can scare you). Later justified when it's revealed that Jack was possessed by a spider-like thing from Zimmy's World that was gradually eating away at his sanity.
A flashback had a student (coincidentally Jack's father) teasing Surma's group after one of them conjured a giant portal. It's confirmed that the portal-conjuring student is a Valkyrie and her "Old Man" is Odin.
Coyote summons Annie to the forest, then reveals that it's only to have her tell him stories about himself. When Annie protests, and suggests that Ysengrin could do just as well, Coyote insults Ysengrin, and then tries to intimidate Annie. Annie flicks Coyote's nose, prompting an Oh, Crap! reaction from Ysengrin and (apparently) sending Coyote into a rage. He's faking, but he then proceeds to set up a situation where Annie almost gets killed by a genuinely enraged Ysengrin.
Annie does this to Coyote a lot: she's well aware of just how powerful he is, but he's such a jokester most of the time that she doesn't take him seriously. Usually Coyote finds this to be hilarious, but it has been hinted that Annie is walking a dangerously fine line in treating him this way.
Stunt and Bumper in Dominic Deegan insistently kept trying to rob the eponymous character, despite them knowing he's a capable magic user who can see the future. The stuff they kept stealing would inevitably be worthless and booby-trapped.
Ralph makes this mistake in Sandra and Woo after being told by a schoolmate that he should really, really not bully Cloud, especially if Cloud is currently carrying a sword... or a plastic knife from the school cafeteria.
The Order of the Stick: Tsukiko does this to Redcloak repeatedly, who is a much more powerful cleric than she is, and he takes it every time until she finally threatens to reveal his plans to Xykon. It ends very, very badly for her. This might fall under Underestimating Badassery, given her (stupid) belief that she has Xykon in her corner keeping Redcloak in line and her (less stupid) belief that her massive spell selection and minions would give an edge in at least escaping. Going up against an epic-level cleric while relying heavily on undead was her biggest mistake, but a massive psychological blind spot to the actual mechanics of undead was a defining trait of hers from the beginning.
Girl Genius had some people mistreating Jägermonsters just because they used to be afraid of Heterodynes' supersoldiers and think they have the upper hand right now. Jägers, while hanged, are more afraid of meeting their own communication officer. Who, naturally, arrives — riding a giant bear — and after she asks politely to enter the town, one guard shoots. After she catches the arrow, another lad screams "fire!", so of course Hilarity Ensues.
The prize, though, goes to the Wulfenbach troops commander who due to being on the wrong end of a Curb-Stomp Battle screams to fall back and wait for airstrike. When a Jäger General looking like Big Red Devil says they're now "asking for it", the bright guy adds an insult to his hometown. Though maybe he just figured out he'd dead either way.
Schlock Mercenary had some alien frat boys picking on Nick — they don't know he's boosted and wears a low-profile powered armor, but he's as massive as three of them put together and obviously in a uniform. Naturally, even someone smarter than him would be surprised that yes, they really are trying to pick a fight. After he threw one to the other end of the corridor, the local security were dumb enough to pick a firefight with this team. This escalates until...
Kevyn: Captain, Sergeant Schlock's team just called in. He said they got the information, but they're pinned down in the library's data center by the local police.
Kevyn: He said they can fight their own way out, but only, and I quote, "Over the steaming ashes of this stupid swat team."
And then there's Petey - or rather, the Deus Est Machina Godlike Fleetmind formed around the Petey AI persona. The galactic core spins at his whim, and a single one of his ship is a match for most other civilization's entire NAVIES. And yet, people ranging from governments to organized crime bosses still think it's a good idea to insult or prod him just to see how he'll react. The only reason he doesn't casually frag them is that he usually has better things to spend his energy on, such as avoiding the utter annihilation of the entire galaxy.
Petey: It's still not worth billions of lives just to kill her, but she really knows how to jump up and down on that scale.
Magick Chicks: Both Faith and her boyfriend, Ash, have made the same mistake with Layla and Brooke, respectively.
Faith didn't realize Layla was a vampire, until after she'd lead her back to her home, under the assumption they had hit it off. But when she vamped out on her, Faith psychically restrained her. She initially planned to stake her, until Tiffany arrived unexpectedly. Which gave Faith the idea to stimulate Layla's rage centers in order to fight her without her powers, citing that they never get any hands-on training, at Artemis. Despite having the upperhand, Faith lost due to having forgotten they were fighting indoors and struck her own head on the ceiling. Thankfully, Tiffany was able to calm Layla down, by allowing Layla to feed on her.
The entire Elvenrace in Errant Story: In the aftermath of the final battle, after being saved from genocide, they threaten the one who nearly single-handedly saved them with death unless she gave up the power she used to save them. Meji, the woman in question, wearily tells them they have more important (and possible) things to do, like rescuing trapped survivors. And if they ever came after her or any other half-elf again, she'd strike them dead with no warning or hesitation.
Everyday Heroes: Alpha Bitch Angela and her girl posse constantly pick on Summer (Super Strength and Eye Beams) and Carrie (super-strong Prehensile Hair), despite the fact that either of them could take her apart with little effort. And also despite the fact that she comes out on the wrong end of those altercations more often than not (verbally and physically).
DNA: Rigel does this to the other kids, even though he doesn't have super powers like the others. It backfires when he does this to Lukas. Sirius tries to protect the others from Rigel, but Rigel doesn't care because this gets Sirius in trouble for fighting.
In JL8, a group of kids playing baseball argue over whether or not they just saw an errant foul ball bounce off Clark's head, without Clark even noticing (It did, and he didn't). One of them decides it would be a good idea or "at the very least... pretty funny" to throw directly at Clark's head to see for sure. Clark probably would've shrugged that kind of dickery off. Unfortunately for him, Diana caught the ball.
Zebra Girl: Gregory is an experienced exorcist and demon-hunter who thought he could drag the emotionally drained Sandra with him to hell. Turns out it was a very bad idea. That event is also what finally drove Sandra over the edge.
Nerf NOW!! has a demon mock the 2016 Doom Marine for his habit of collecting dolls. Said demon has a shotgun down his throat the next panel.
Meat Shield: Dhur's older brother, Ghar, who has a habit of unsubtlely insulting his half-orc little brother's intelligence to his face. Repeatedly. When Jaine tries to clue Dhur in that Ghar wasn't "just joking", Ghar's mother Mona stops her, telling her that she convinced Dhur of Ghar's kidding when they were younger "so he wouldn't rip Ghar's arms off."
In Ozy and Millie, Jeremy's father challenges Llewellyn (an actual fire-breathing dragon almost twice his size) to go outside for a fight. Llewellyn ends up incinerating Jeremy's dad's Porsche because he has to sneeze due to the cologne that Jeremy's dad wears.