- "Funny Aneurysm" Moment: Any of the Self-Deprecation jokes that John Pinette made about being fat stopped being as funny after he died of heart disease in 2014.
- Germans Love David Hasselhoff: Has a fanbase in Latin America, thanks to airing on animation channel Locomotion.
- Growing the Beard: Arguably, the later half of season 3 is when the show really improved; the energy level was higher, the father/son tension between Dr. Katz and Ben was lessened, the improvised dialog was more tightly edited to produce the most laughs, and Laura periodically lightened up a bit. In her own way, of course.
- Harsher in Hindsight: One of guest Jon Stewart's bits was how America needed a new enemy, now that communism isn't relevant. The episode in question was from 1996; only five years later, America would get an enemy in the form of Al Qaeda. And we can't forget about North Korea...
- Hilarious in Hindsight: One episode had Dr. Katz and his son humorously discussing horror movies where the killers were little people. In 2009, Warner Brothers released Orphan.
- The last episode of the series concerned Dr. Katz noticing that Conan O'Brien used his jokes in a monologue on his show. Guess what happened in 2017?
- Jon Stewart had a bit about how the U.S. should make Canada its enemy. This is three years before such a thing was a plot point in South Park: Bigger, Longer & Uncut.
- Ho Yay: Dom Irrera constantly hits on Katz.
- Older Than They Think: A lot of the veteran comedians' material has been part of their act since the '80s. It's not uncommon to watch an old Johnny Carson episode and see a comedian doing a routine that would be done in Dr. Katz ten years later.
- Padding: "Day Planner" ended up this way, largely because guest Rodney Dangerfield only gave the staff about three minutes of material to work with. This is why there are two other guest stars in the episode, to make up for the shortage of Rodney material.
- Spiritual Successor: With its largely improvised dialogue and conceit of comedians playing themselves, Dr. Katz definitely feels like the spiritual predecessor to Curb Your Enthusiasm.
- Comedy Central's Shorties Watching Shorties was basically the same premise: Animating the audio of stand-up routines. It was produced by a different company, though, and was animated in Flash instead of Squigglevision.
YMMV / Dr. Katz, Professional Therapist