Blister: Hey, Dummy! If you're reading this then that probably means I'm not around anymore. I bet you're crying like a baby, right? Heh, Sucker!
— The first sentence of Blister's farewell note from "Later, Dingus".
As a Moments subpage, all spoilers are unmarked as per policy. You Have Been Warned.
- Whenever there's an episode centering on Dade, you can expect moments of this. He's pretty much a textbook Jerkass Woobie who is often picked on by the twins because of his socially awkward personality and the fact that he's overshadowed by his siblings. His tearful meltdown in "Wade Is Cooler Than Dade" after Wade manipulates him into humiliating himself in front of everyone and his deranged reaction to having his name erased off a menu in "The Dade" will make you pity the poor guy. Then there's his parents' love speech to Harvey in "The New Bugaboo" about just how lonely and unnoticed he feels.
- Fee, another Jerkass Woobie, has her moments as well. One being "The Grunicorn", in which the characters search for a legendary wish-granting creature. Fee in particular lies about the wish she plans to make, while Rooter's wish is that the titular grunicorn would leave so that his friends wouldn't be so lazy as to wish for what they could earn by working. After the two are trapped in one of the latter's traps, Fee eventually breaks down and admits what her wish really was: Parents. Rooter, touched, throws Fee to freedom so she could make her wish. In the end, Fee comes back for Rooter, who in turn suggests she say her wish aloud so that it could be heard and granted. It concludes with Fee doing just that.
- In "Later, Dingus", Blister passes away. Knowing his jestful nature, Fee of course assumes it is a prank. Later after crashing his funeral, she along with Harvey and Foo anticipate Blister will appear...he never does...and Fee waits all day for him until Miriam brings her a box of his belongings. Realizing the truth, Fee finally breaks down to tears (And so do the audience.) while Harvey and Foo console her. They soon find blueprints for a prank, so they pull it off as a way to honor Blister. Yes, it has its share of silly moments like any other episode, but it portrays death in a tactful manner; Fee loses someone she bonded with as a friend and copes with the pain as one would in real life.
- There's also the memoriam at the end of the crew members' deceased friends and relatives.
- The Bittersweet Ending of The End and the Beginning. Fee and Foo are reunited with their parents, but have to move away from Little Bark. Harvey gets pretty saddened about them leaving, but he does know that he was lucky to be their friend. (Plus, they still get in contact with each other through mail letters.) It's both sad and heartwarming to see Harvey's flashbacks to his adventures with his two best friends, and how they changed his life.Irving: Sometimes people come into your life, and sometimes they have to leave.
Harvey: It's so sad.
Miriam: It is sad. But you're also really lucky you got to be their friend. Nothing's ever going to change that.
Irving: Yeah, you found each other. When a friend comes into your life, it changes you a little. They challenge you. They make you laugh. They make you stronger. Each person gives you a gift. A special part of them that you keep forever. It's like they're always with you.- Even more bitter given the show being Screwed by the Network, all because Nick has highly unreasonable expectations that all modern Nicktoons absolutely must pull in the same ratings as SpongeBob SquarePants and The Loud House, or else they're viewed as expensive failures, even if said Nicktoons manage to beat shows on Cartoon Network and Disney XD in ratings.
