While not as common as human-demon or human-angel hybrids, the concept of humans interbreeding with monstrous creatures beyond typical understanding isn't unknown. After all, Even Evil Has Loved Ones: it's common for creatures like demons, no matter how evil, to have a soft spot for their hybrid children and can be reasoned with by them. In contrast, Eldritch Abominations operate on an entirely different system of morality and values than humanity.
While human-demon and human-angel hybrids typically struggle with an innate tendency towards good or evil (real or imagined by others), those descended from Eldritch Abominations tend to be fundamentally alien in how they perceive and interact with the world. Antagonists of this sort often inherit their inhuman ancestor's views on humanity, and cause harm through indifference rather than malice.
They are often Eldritch Abominations or Humanoid Abominations themselves, especially if they are first generation descendants. Even if they resemble their human side more strongly, they often possess Lovecraftian Superpowers.
How these people come to be in the first place given the vast difference in biology between their human ancestor and their Eldritch Abomination one is typically not fully explained. In some cases, it's explained as the abomination having taken a humanlike form, temporarily or otherwise, while in other cases, the mechanics of how such a thing could occur is merely ignored or excused by the abomination's godlike powers.
Contrast with Transhuman Abomination, where a human becomes an abomination rather than being descended from one.
Anime & Manga
- Naruto: Hagoromo Ōtsutsuki, the legendary Sage of Six Paths who invented most of the ninja arts used in the setting, and his brother Hamura, were the children of Princess Kaguya, a celestial being with godlike power who originally came to Earth with the intent to destroy it and all of humanity before she found herself growing fond of it.
- "The Dunwich Horror": Both Wilbur Whateley and his brother are the offspring of a human woman and Yog-Sothoth, one of the Outer Gods of the Cthulhu Mythos. While Wilbur Whateley can pass for human, at least as long as his clothes stay on, his brother is an giant invisible tentacled monstrosity whose only human features are his face.
- Whateley Universe: Carmilla is a supernaturally attractive young woman with Combat Tentacles, psychic powers, and the ability to shapeshift: her abilities come from being related to Eldritch Abominations on both sides of her family tree. Her grandmother on her father's side is Shub-Niggurath, and her mother is a descendant of Cthulhu.
- South Park: Kenny is revealed to be part eldritch being in the Coon saga, where it's revealed his immortality comes from his parents attending a Cthulhu cult before his birth, causing Cthulhu to embed a part of himself in Kenny. Whenever the latter dies, his mother gives birth that night to an identical baby Kenny, who rapidly ages in the night.