General

Jason Carl calling Seattle by Night "Gothic Grunge."
The group generally jokes around and has a lot of fun with out of character statements as well as joke.
The constant shade the group throws on Tacoma.
Jerry Holkins spending a good ten minutes of the first session of Season 2 describing his Masonic Lodge haven and the surrounding neighborhood that is full of hipsters.

Amanda

Amanda taking notes about Kindred lore on a yellow pad. This is a homage to LA By Night's Annabelle, who did the same thing.
Amanda being consulted on the occult when she clearly knows absolutely nothing, just because she's Tremere.
Amanda getting "delivery" of a vessel as sent by her father. The vessel assumes she has a rare blood disease and that he can help by donating blood.
Amanda yelling at her dad in Elysium when she discovers he's a ghoul.
All the shade Amanda gets for "sleeping" with a Giovanni.

Much is made of the fact Tom wears socks with Crock.
Tom continues to eat two-dollar nachos, throw them up, and keep eating them because he doesn't realize vampires can't eat food.
Tom vomiting up a banana milkshake up on the Brujah Anarch Remy.
Tom taking his shirt off in Elysium to show off his body art to a Toreador.
Tom creates a taco/blood blend with a centrifuge in the Tacoma hospital.
In Season 2, episode 1, Tom explains how he's heard of wights.
"I played a lot of D&D."
In Season 2, episode 3, Tom attempts to find orange juice and hot pockets in Jamison's fridge.
In Season 2, episode 3, Tom asks some interesting questions about social media.
"Should I send her a picture of my penis?"
In Season 2, Episode 4, he has a Mushroom Samba encounter with Cherry Moon and ends up "hugging the moon."
In Season 2, Episode 6, Tom attempts to buy Cherry Moon (a Thin Blood drug) from a local drug dealer who directs him back to where they normally get it.

Betty lives in Bellevue and the cast says this explains everything about her.
Betty asking if it's too late to get on the ground floor of Uber.
Betty completely flubbing her rolls to try to get a read on Mr Drew. And then getting pissed off enough by said failures that she threatens to take her lipstick to his suit coat get him to talk - which is what gets him to crack.
Betty telling Amanda her father is a very sexy man. Then explaining to her that he's a ghoul even if that's a rude word.
Betty planning to murder a guard with a straw in order to avoid having to drink his blood directly. Thankfully, she's talked out of it.
Her Moral Myopia at being disgusted at feeding the "other way" (i.e. with the Kiss) and the guard asking if it was good for her too.
Betty complaining about how "you brought a girl flowers" before you drink someone's blood.
In Season 2, Episode 4, Betty explicitly denies having any Belligerent Sexual Tension with Dahvid while doing a bunch of hilarious double entendres like how he's going to finger the group.
- She insists she could never be involved with him because he wears a turtleneck.
In Season 2, Episode 4, Betty reacts with her Team Mom energy to finding out the group has knocked the Prince's enforcer, Rafe, into torpor.
In Season 2, Episode 6, Betty feeds Jamison horse's blood as a pick me up.

Betty, having interposed a waiter between herself and a falling chandelier, shoves her not-long-for-this world meat shield over to an injured Amanda and Jamison. Without hesitation, Jamison unhinges his jaw, locks eyes with Amanda, snarls "Don't," and begins to feed.
In Season 2, Episode 1, Jamison attempts to explain how to woo women through the power of texting and the secret that all women crave is the animated gif.
In Season 2, Episode 3, Jamison has a bizarre digression about his time hanging out with the Rat Pack that ends with him singing.
In Season 2, Episode 6, Jamison drinks some horse's blood and ends up believing he's developing horse-like qualities as a result, including desiring to sleep standing up in a stable.

Enrique's obsession with figuring out whether Betty has other people regularly in her car or not causes the entire first session to stop for a few minutes as everyone finds it a horrible invasion of privacy.
Enrique receives much praise from the group when he finally gets the classic Seattle put down of, "The bathroom is for customers only."
In Season 2, Episode 7, Enrique describes his character as "chaste" only to the vicious mockery and eye rolls of the rest of the cast. Including Jason!