His character in Commando confronts an unusually confident bad guy sitting in a chair moments after his associates have kidnapped Arnie's daughter. "Moments" being the key word here— Arnie just shoots the guy and chases after the kidnappers in his truck. Oops.
In the end of Conan the Barbarian (1982), villain Thulsa Doom (played by James Earl Jones) proceeds to tell Conan (played by the aforementioned Arnold) that he is the most important person in the barbarian's life, and without all the things he did to Conan (killing his family, selling him into slavery), he would not have turned out as awesome as he is. Conan's rebuttal? He uses what's left of his father's sword to chop Doom's head off.
End of Days (1999). "The Man" (Gabriel Byrne) is giving Jericho Cane (Arnold Schwarzenegger) his temptation speech (he is The Devil after all) and trying to convince him that a satanic apocalypse wouldn't be so bad after all.
The Man: Just tell me what you want.
Jericho Cane: I'll tell you what I want. I want you... to go to Hell.
Jericho Cane: Oh, you think you're bad, huh? You're a fucking choir boy compared to me! A CHOIR BOY!
The Exorcist III. Kinderman interrupts The Gemini Killer's Break Them by Talking by wordlessly interrupting him with a punch to the face that breaks his nose. The Gemini is unperturbed ("Ooooh, a few boos from the peanut gallery.")
300: After the Persian messenger has delivered his threats, Leonidas bellows "This! Is! SPARTA!" and kicks him down a well. More of a Hot-Blooded challenge of "Bring it on!"; what else would you expect from Spartans?
Just before the battle, a Persian messenger is said to come to the Spartans offering a chance to surrender. When Leonidas refuses, the messanger says "Our arrows will block out the sun!" To which Stelios replies "Then we will fight in the shade."
Also in the scene where when asked to "lay down your weapons" King Leonidas responds with "Come and get them!" which is allegedly what he laconically said in the historical battle.
The ending to The Dark Knight where the people trapped on two ferries refuse to play along with Prisoner's Dilemma, deciding to not to blow the other ferry up, even with the threat of the Joker blowing them both up at midnight, their decision proving the Joker's Humans Are Bastards viewpoint wrong. Even cooler is that one of the ferries has prisoners on it, and a stereotypical Scary Black Man just says no.
The Joker: We really should stop this fighting. Otherwise, we'll miss the fireworks! Batman: There won't be any fireworks! The Joker:(expecting one of the two ferries to explode) And here we... go! (neither ferry explodes and the Joker looks out at them, confused. He turns to a small clock and realizes that it is past midnight) Batman: What were you trying to prove? That deep down, everyone's as ugly as you? You're alone.
Followed shortly by:
Joker: You can't rely on anyone these days, you've gotta do everything yourself, DON'T WE! Luckily I came prepared. [wips out a third, long-distance detonator] It's a funny world we live in. Speaking of which, do you know how I got these scars? Batman:No. But I know how you got THESE! (Batman shoots the Joker with his gauntlet blades)
"He died screaming, like a stuck Irish pig. Now you think about that when I beat the rap."
...telling him to shut up isn't enough. Ness shoves him off the roof.
In Girl, Interrupted the antagonist Lisa, whom the others see as a something of a Badass, stalks the heroine Susanna through the labyrinth beneath the mental institution. She gives an increasingly unstable speech about how free she is and how easy it is to push people's buttons.
Lisa: You know, there are too many buttons in the world. There's too many and they're just... There's way too many just begging to be pressed. [....] And it makes me wonder. You know, it really makes me fuckin' wonder, why doesn't anybody ever press mine? Why am I so neglected? Why doesn't anybody reach in and rip out the truth and tell me that I'm a fuckin' whore, or that my parents wish I were dead? Susanna: (whirls around) Because you're dead already, Lisa! No one cares if you die, Lisa, because you're dead already. Your heart is cold. That's why you keep coming back here. You're not free. You need this place. You need it to feel alive. It's pathetic.
And it doesn't stop there.
Susanna: I've wasted a year of my life. Maybe everyone out there's a liar, and maybe the whole world is stupid and ignorant, but I'd rather be in it. I'd rather be fucking in it than down here with you.
The Leprechaun:(to Emily, who's dangling from a rooftop) For two-thousand years you filthy mortals have tried to steal my riches to satisfy your greedy urges... and it always ends the same, with you begging for your miserable lives. Was it all worth it in the end? One day your kind will learn that the treasure of the Leprechauns— Rory: Hey! The Leprechaun: Huh? (gets shot in the chest several times by Rory)
The Good, the Bad and the Ugly: A vengeful adversary, whose hand Tuco previously shot and permanently disabled, catches Tuco naked in a bathtub. He delivers a long speech about how he tracked the bandit down, and how he had lots of time to learn to shoot with his left hand, which is cut off when Tuco shoots him with a gun hidden under the bathtub bubbles.
Aleera: Anna, my love. It is your blood that shall keep me beautiful. What do you think of that? (laughs triumphantly, then screams as Anna catches a silver stake and impales her through the chest) Anna Valerious: I think if you're going to kill somebody, kill them! Don't stand around talking about it!
Taken 's biggest Crowning Moment Of Awesome is just that. At the end Bryan gets to the fat sheikh that has bought his kidnapped daughter as a sex slave. He puts a knife on the girl's neck and attempts to negotiate, but Bryan just shoots him in the head before he completes the third word.
M has a villainous example, as Hans explains to his captors why they're no better than him and have no right to judge him, but they don't listen.
In the movie Breakdown, the Big Bad starts to threaten the hero and his wife (the latter having just been rescued from the chest freezer in which the villains left her to suffocate) only to be silenced nine words in when a severely stressed-out Kurt Russell screams "You FUCK!!!" and kicks him in the face.
In the film-version of The Lord of the Rings: Return of the King, the Mouth of Sauron shows the heroes Frodo's mail-shirt, and laughs and lectures them about how Frodo suffered before he died; in response, Aragorn just chops his head off, then declares to the others that he will not believe it.
In what has to be one of the most epic demonstrations of this trope possible, the Lord Marshal in The Chronicles of Riddick puts down a naysayer by ripping out his soul and showing it to him before casting it aside. The guy drops dead on the spot and the entire assembly is cowed into submission.
Also note that as this planet was a religious melting pot, his actions are particularly effective.
Minority Report features one of these at its climax as the villain tells John Anderton his reason for setting him up to be arrested for murder:
Lamar Burgess: Think about all the lives that little girl (Agatha) has saved! Think about all the lives she will save! That little girl could have saved Sean!
In, A New Hope, when Greedo encounters Han Solo in the Mos Eisley Cantina, his threat to take the Millennium Falcon over Han's dead body prompts Han to shoot and kill him.
Vader puts Admiral Motti in his place.
Motti: Don't try to frighten us with your sorceror's ways, Lord Vader. Your sad devotion to that ancient religion has not helped you conjure up the stolen datatapes. Or given you clairvoyance enough to find the Rebels' hidden fortre-
Vader: Give yourself to the Dark Side. It is the only way you can save your friends. Yes...your thoughts betray you. Your feelings for them are strong, especially for...sister! So you have a twin sister. Your feelings have now betrayed her too. Obi-Wan was wise to hide her from me, now his failure is complete! If you will not turn to the Dark Side, then perhaps she will-
Luke: [ignites lightsaber and comes out of hiding] NEVER!!
And topping it all is the one he gives to Emperor Palpatine, defying the old bastard good and hard:
Luke: No. I'll never turn to the Dark Side. You've failed, your Highness. I am a Jedi. Like my father before me.
In the novelization of Revenge of the Sith, Grievous tries to intimidate Obi Wan by stating "I've been trained in your Jedi arts by Count Dooku!", to which Obi Wan answers, "How interesting. I trained the man who killed him."
In Kate Bush's The Line, the Cross and the Curve, toward the end:
Miranda Richardson: We have a lot in common, you and I. It took me years to be rid of those shoes! You are so weak. So stupid. So...
Kate Bush: You're scared. You're scared, because you know you're losing your power over me.
John Frankenheimer's Seven Days in May; toward the end, when the conspiracy to overthrow the President is uncovered, General Scott accuses his former underling, Colonel "Jiggs" Casey, who blew the whistle on him, of betrayal:
Gen. Scott I asked you a question - do you know who Judas was?!? Col. Casey Yes, I know who Judas was - he was a man I worked for and admired until he disgraced the four stars on his uniform.
Kiss Kiss Bang Bang: Harry interrupts Mr. Fire's "tough guy" speech with a few bullets to the chest.
In the final confrontation of Scream 3 the killer rants at Sidney about how her mother brought her death on herself, and how none of this is his fault. She interrupts him in a CMOA, he doesn't take it well.
Sidney: God, why don't stop your whining and get on with it? I've heard all this shit before!
Sidney: Do you know why you kill people Roman? Do you?
Colonel Vogel: Tell me about this miserable little diary of yours. (slaps Henry Sr. with his glove) We have the map, the book is useless and yet you come all the way back to Berlin to get it. Why? (he slaps Henry again) What are you hiding? (he slaps him again) What does the diary tell you that it doesn't tell us?
(he tries to slap him again, but Henry grabs his wrist, stopping him)
Professor Henry Jones Sr.: (through his teeth) It tells me that goose-stepping morons like yourself should try reading books instead of burning them!
Batman does the same thing. Instead of a gun, he just punches the guy out.
Hannibal Lecter did indeed get this reaction a couple of times. Ironically, the most literal example (in Hannibal) was not as dramatic as many other examples for this Trope:
Lecter: Good evening, Clarice! Just like old times.
Starling: Shut up.
In Red Dragon, Hannibal tries to pull his trope on Will. Will simply wishes him goodnight and leaves the room. This might be the only way to win (or draw) against the great Hannibal Lecter; he fancies himself being able to understand anyone, so simply ignoring him and his 'genius' is the best possible retort.
Hannibal himself does in in response to Mason's To the Pain speech in Hannibal. Obviously, it was neither the time nor the place for his usual Trope. (Crazy doesn't mean stupid.)
Played with in Mystery Team; Robert interrupts Jason's speech about why they are all going to survive by SHOOTING HIM.
In Transformers: Dark of the Moon, Sam finds himself facing off against Dylan Gould, a human who has agreed to assist the Decepticons in their takeover of Earth, provided that he is unharmed after the takeover (and possibly gets a fair share of the spoils; such as being leader of the human slaves). Sam tries to reason with Dylan, who ignores his pleas and turns on the final Pillar for the Space Bridge, warping Cybertron into Earth's atmosphere. Dylan then kicks Sam to the ground, telling him "You chose a side? You chose wrong!" Moments later, Sam appears with a metal bar in his hands, leading to this final conversation:
Dylan:See that? (Points to Cybertron) I just saved a whole other world! You think you're a hero? You think you're a HERO!?"
Sam:No... I'm just the messenger! (Rams Dylan with the metal bar, causing Dylan to collide with the Pillar's energy beam, electrocuting him to death.)
Gideon Graves: Who do you think you are, Pilgrim? You think you're better than me? Well, I'll tell you want you are. A PAIN IN MY ASS!!! You have any idea how long it took me to get the evil exes' contact information so I could form this stupid league? Like two hours! TWO HOURS!!! (coughs up some quarters) You're not cool enough for Ramona. You're zero! You're nothing! Me? I'm what's hip! I'm what's happening! I'm blowing up right now!
Scott Pilgrim: You are blowing up... RIGHT NOW! (punts Gideon in the head, killing him)
In the original Dirty Harry, the title character is held at gunpoint by Scorpio, who plans to kill him after a good bit of Evil Gloating, but before he can get the chance, Harry stabs Scorpio in the leg.
And for added humor, Scorpio lets out a huge girly scream.
The 2009 remake of Night of the Demons has a literal example when the protagonist Maddie is cornered in a magically-protected room by Angela (who's possessed by the lead demon), who goes into a rant about how how Maddie and her friends are going to suffer horribly before they're possessed. Maddie's response?
"Shut up, bitch." (slams door in Angela's face)
During the Final Battle at the climax of The Matrix, Smith knocks Neo to the floor and proceeds to give a nihilistic rant that concludes with "Why, Mr. Anderson?! Why?! Why do you persist?!" Neo's response is a very simple Call Back to his last conversation with the Oracle that perfectly shoots Smith down.
At the climax, Loki is cornered by the Hulk, who has just finished tearing through half of Loki's army. Loki, furious, seeths that he is a god and not someone to be bullied by a green simpleton who At this point, Hulk grabs Loki and smashes him around the room which leaves him lying in a Loki-shaped crater on the ground struggling just to breathe.
The Truman Show's climax, where the eponymous show's producer, Christof, attempts to convince Truman to stay in the manufactured world he made for him, which is produced for television 24/7. Truman is stunned, but does give one hell of a great comeback:
Christof: There's no more truth out there than there is in the world I created for you. The same lies, the same deceit. But in my world, you have nothing to fear. I know you better than you know yourself...
Truman: You never had a camera in my head.
A Few Good Men: At the very end, when Jessup is arrested for Santiago's death, he coldly accuses Kaffee of only succeeding in weakening a country.
Kaffee: Don't call me son. I'm a lawyer, and an officer in the US Navy. And you're under arrest, you son of a bitch.
Lightning: Oh, like you? You've been here how long and your friends don't even know who you are? Who's caring about only himself?!
Doc Hudson: Just finish that road and get out of here!
Doc suffers further humiliation after it is revealed that he was the one who tipped off the media to McQueen's whereabouts so they can pick him up and take him to his big race, while Doc himself can avoid being recognized.
Tony does this in the novelization, throwing Ivan's words about being a thief and murderer back in his face.
He pulls this off in the movie, as well, when he visits Vanko in his holding cell.
Ivan: The truth: all I have to do is sit here and watch as the world will consume you. Tony: Where are you gonna be watching the world consume me from? Oh, right, a prison cell. I'll send you a bar of soap. Don't drop it.
The Graduate: Mrs. Robinson is a lonely, depressed, alcoholic housewife that had to give up on her artistic dreams when she got pregnant and married young, and she apparently feels that since she had to suffer a Shotgun Wedding because of her daughter Elaine, then she should force Elaine to have one too. The wedding takes place, but Elaine decides to be a Runaway Bride anyway, so her mother reminds her that she is already married.
In Disney/Frozen, Anns stops Prince Hans from killing her sister, Elsa, but at the cost of her own life — she becomes a frozen-solid statue, which shatters Hans' sword he intended to use to kill Elsa. Then Elsa manages to control of her powers and thaw out Anna through the Power of Love. Hans is quite aghast to see them both alive.