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Typhoid Mary
The Typhoid Mary is a character who carries an infectious disease but doesn't suffer any visible symptoms — in some cases she may actually be immune to it herself — and spreads the disease to everyone she encounters.

Unlike the Plaguemaster and Poisonous Person, the Typhoid Mary isn't a villain. She doesn't intentionally try to spread her infection, and is often unaware that she is infected at all, especially when he is an asymptomatic carrier like the original Typhoid Mary. She is at worst Obliviously Evil, stubbornly refusing to believe she is a carrier, let alone cooperate with public health authorities.

However, villains may try to use the Typhoid Mary as a weapon, deliberately infecting an unsuspecting person with a contagious disease so she can unknowingly spread it to others. If she was in fact the first person who was infected she may be the Patient Zero and possibly be the key to curing it. Thus she can be the target of an all-out manhunt to contain her before everyone around her is infected.

In Zombie Apocalypse works, there may be some overlap with the Zombie Infectee, depending on how the infection spreads. In most cases, however, the Zombie Infectee doesn't pose a danger of infecting others until he actually dies and become a zombie himself. The Typhoid Mary, on the other hand, is highly contagious from the first moment of her infection.

The Trope Namer is the Real Life example of Mary Mallon, the original "Typhoid Mary" who spread typhoid fever to at least 53 other people while refusing to believe she carried the disease at all, because she never became sick from it herself. In biology/epidemiology this is known as an "asymptomatic carrier" (i.e. carries the disease but shows no symptoms of it).

Not to be confused with the Daredevil villain of the same name.


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    Anime & Manga 
  • In the second episode of Memories, a man takes an experimental drug that causes anyone near him to die instantly. He never realizes he's dangerous, and seems quite upset that everybody's trying to kill him.

    Comic Books 
  • Italian comic book Dylan Dog had a short story about a girl born into a werewolf family. While not a werewolf herself, she was a carrier of lycanthropy - anyone who came into contact with her internal fluids (including through sex) would be infected.
  • Averted in an issue of The New Teen Titans; a young Russian woman is sent to run errands in New York City, while unknowingly infected by her boss to spread disease in America. Unfortunately, she gets progressively sicker as she goes along, and once the Titans catch up to her, she is the only one who can't be cured.
  • In one Bad Future of Batman, Damian Wayne faces his greatest challenge as Batman when a Joker virus drives the people of Gotham insane. All except for one baby boy. Barbara Gordon tests the baby and can't find any symptoms of Joker virus at all. Damian visits Gorilla Grodd and demands that he help synthesize a cure for the Joker virus using the baby. Grodd reveals that the baby is actually a carrier of the Joker virus. Cue Joker Barbara killing the baby and opening the doors for the mob of lunatics.

  • Jack from Transporter 2 was turned into one by the villains as part of an assassination plot.
  • Love Interest Nyah from Mission: Impossible II was going to be used as one by the villains. She knew it, however, and was ready to kill herself rather than spread the disease. Luckily, Ethan got her the cure in time.
  • In 28 Weeks Later, Alice is an asymptomatic carrier of the Rage virus, which results in it breaking quarantine.
  • This was the central plot driver in REC, where no one knew that the little girl didn't actually have tonsilitis, but something far far worse.
  • In Kids, one of the characters is a sexually promiscuous teenage boy who doesn't know he's HIV-positive.
  • Patrick Dempsey's character in Outbreak unwittingly infects a plane-load of people he's travelling with after he catches the virus from a monkey.
  • Anthony Wong's Villain Protagonist character from Hong Kong exploitation movie The Ebola Syndrome contracts the eponymous sickness, but turns out to be a one-in-a-million case whose immune system fights it off while remaining contagious, and unknowingly spreads it around in South Africa and Hong Kong. Towards the ending, he becomes aware of his condition and starts to spread it willingly, but by then he's been long confirmed to be pure evil.

  • Lenie Clark of Peter Watts' Rifters Trilogy series carries βehemoth back to the surface world. However she isn't a proper example, since she spreads it deliberately.
  • The protagonist of Peeps carries a parasite that transforms anyone he gets too intimate with into a vampire. Now that he knows, he's careful not to spread it, but he had already infected a number of people before he found out he had it.
  • Geoffrey Allen from The Changeling Plague. He gets a retrovirus engineered to cure his cystic fibrosis. Since it was specifically designed for his DNA, it has only positive effects on him. But unbeknownst to him, he's also spreading to other people...
  • The novel Code Orange revolves around a teen who fears he may be a carrier of smallpox.
  • In Wild Cards, Croyd 'The Sleeper' wakes up with the ability to spread a new strain of the Wild Card virus; one where people who have aready been transformed with Wild Card can be re-infected and changed all over again. Croyd keeps moving and spreading the virus because he had entered the paranoid stages of his meth addiction, and can't trust anyone.
  • Stephen King's The Stand has several unwitting Typhoid Marys but "Joe Bob" Brentwood is the most important as he unintentionally spreads the superflu beyond any chance of containment.
  • The rabies-spreading Rant Casey, of, well... Rant. In fact, the book compares him to Typhoid Mary several times. However, he seems to actually want to spread the disease... unless he doesn't... it's a little complex when you don't know there's technically two THREE of him.
  • In the Temeraire series, the British government exploits this by infecting a French dragon with a highly contagious plague and sending it back to its home base to spread the disease.
  • Miss Sneezy's story in Haunted 2005 is about an island facility where examples of this trope from all over the country live in sterile, high-security isolation. And yes, she is one of them.
  • In Wyvern by A.A. Attanasio, one character finds that every village he stays at is struck by fever, although he never gets sick himself. He is finally taken in by a Buddhist monastery, and although the monks get sick, they teach him how to treat the illness. Finally, he administers the cure to himself, and from then on nobody else gets sick by having contact with him.
  • World War Z had carriers' organs being harvested and sold on the black market, spreading the infection across the world.
  • Thura in the Redwall book Salamandastron; probably his partner-in-crime Dingeye as well, but he never got the chance to show symptoms.

    Live-Action TV 
  • The Star Trek: The Original Series episode "The Way to Eden" featured Dr. Sevrin, carrier of the Synthecoccus Novae virus who was more crazy in the coconut than malicious. While the episode didn't have any reported infections, this was because Federation citizens were immunized against the disease. The problem was that Sevrin wanted to go live on a primitive planet whose inhabitants were susceptible to the disease and did not have any immunities. Kirk orders him to be arrested and isolated which causes Severin's followers to get very angry.
    McCoy: All the others are clear. He doesn't have it. He's a carrier. Remember your ancient history? Typhoid Mary? He's immune, as she was, but he carries the disease and spreads it to others.
    • Spock in the episode "Miri", although he never actually spreads the disease he passively carries, simply because everyone else around him is infected too.
  • An episode of House had an old lady volunteer at the hospital handing out teddy bears and unwittingly spreading echovirus. She barely had any symptoms, and healthy adults were unaffected, but it was lethal to newborns.
  • In Dark Angel, Original Cindy's girlfriend was turned into one and eventually died from it.
  • The X-Files:
    • Given an I'm a Humanitarian twist in episode "Our Town", a town of cannibals catches Cruetzfeld-Jakob disease by serving up an infectee at a ritual banquet.
    • In episode "Jump The Shark" is about a biological terrorism plot based on sending out two Typhoid Maries. (Unusually for the trope, they are both fully aware and willing participants).
  • In Stargate SG-1, before the Ori gain the ability to attack Earth directly, they try infecting an SG team with a virus. When the team returns to Earth, they bring the disease back with them.
  • In an episode of Scrubs, an incompetent intern spends the whole week nearly killing patients until JD has a heart to heart with him and tells him that medicine isn't for him. But on his way out, the intern absent-mindedly picks up and bins a dropped medical tissue, then shakes hands with a recently-cured (and very beloved) patient, which gives her the infection that ultimately kills her.
    • In another episode, three people die after organ transplants because the donor unknowingly had rabies.
      • The organ donor variant has also been used on Law & Order and NCIS, usually with black market human tissues and cancer.
  • In an episode of ER, one of the doctors spread a staph infection by not washing his hands adequately between patient visits.
  • The Trope Namer appears in 1000 Ways to Die.

  • In the play Damaged Goods by Eugene Brieux, a man diagnosed with syphilis ignores his doctor's warnings to put off his announced marriage for a few years, and is able to keep his disease a secret until his child is diagnosed with it.

    Video Games 
  • In Metal Gear Solid, Solid Snake was unknowingly infected with FOXDIE to kill the members of FOXHOUND and the ArmsTech President Kenneth Baker.
    • This became a plot point in Metal Gear Solid 4 when Snake's accelerated aging causes the virus to mutate; given a few more months, Snake would have become a one-man plague. He was then infected with a second strain of the FOXDIE virus which helped cancel out the old virus.
  • On a wall in Left 4 Dead 2, some wall graffiti purports that some people are carriers of the zombie infection. It's loosely implied that the survivors might be carriers.
    • Confirmed in the comics for "The Sacrifice": the original Left 4 Dead survivors learn that they've been spreading the infection across the country and may have inadvertently doomed everyone who helped them in the previous campaigns.
  • The above may have inspired both the character of Yerema in Dead Island and The Reveal that the player characters are also uninfected-looking carriers in Dead Island: Riptide.
  • Another Zombie Apocalypse example is the Dead Rising series: the plague was brought to America by orphaned children (who, in turn, were brought to America by Carlito Reyes) who were infected by the viral agent, then placed in a government adoption program. Then, all hell broke loose, (at least) Willamette and Fortune City went to hell, and the rest is history.
  • The Elder Scrolls III: Morrowind: An example of this can be found while pursuing the Temple quests, the player may be asked to tell a woman blessed by the gods that she is a carrier of the Body Horror disease Corprus. The issue in this case was that she didn't believe she was because her state as a blessed person meant she didn't suffer the symptoms, but those around her would still catch it.
  • During the Mogloween 2011 event in DragonFable, The Hero meets a little boy named Andy. Poor Andy is the only person who managed to escape from a Zardbie outbreak, but not unscathed. For some reason the bite he suffered hasn't mutated him into a Zardbie, but anyone who kisses him (happens twice because girls find him too adorable) or anyone he bites (such as a Gorillaphant) becomes a Zardbie. A bad situation becomes worse when one of the people Andy unwittingly mutates is needed to make the Zardbie cure...
  • Zero from the Mega Man X series is the original carrier of The Virus that turns Reploids into bloodthirsty Mavericks. Not only is he immune to its effects (when The Virus becomes a semi-regular enemy in X5) but, in an aversion of Gameplay and Story Segregation, it actually empowers him. Plus, according to the story bridging the X series with the Mega Man Zero series, that kind of immunity was what made scientists try to study Zero's body, and finally create a cure.
  • In Trauma Team Rosalia is one of these to a degree. Even after she was killed, her blood had seeped into the ground, into the flowers, and then made the monarch butterflies become carriers of her Rosalia Virus disease. Those butterflies then spread the disease through their shed scales.
  • Touhou's resident Plague Master Yamame Kurodani is actually a friendly youkai who doesn't use her powers without reason, but her Power Incontinence causes her to spread disease anyway. As a result, she overlaps with this trope.
  • Hatoful Boyfriend's "Bad Boys Love" storyline elaborates this as the backstory for Fujishiro Nageki the mourning dove, who unwittingly carried a virus harmless to birds but fast-acting and lethal to humans. Upon learning of this, Dr. Shuu experimented with turning him into a bio-weapon against humanity, which drove Nageki to suicide.
    • In the same route, we also learn that Ryouta, who already had a slightly weak immune system and weak stomach, got unknowingly experiemented on by Shuu, to make him a good carrier for the virus. He eventually implanted Nageki's liver into Ryouta, having him turn into his next Typhoid Mary.


    Web Original 
  • In The Gamers Alliance, while staying in Alent, Rhylian learns that she is a symptomless carrier of the Blood Fever and has thus infected several of her elven kin with the fatal disease throughout her journey.
    Waldheim: My lady...everything I suspected—everything I feared—has proven to be correct. It wasn't Nesa that infected Killian or Nalaen, or that poor elf in Vanna, or...probably countless others elsewhere. And now, an ever-growing number here in Alent. It was you. you.
    Rhylian: No. You're wrong, Waldheim. How can this be? I've never been sick, how can...? No...
    Waldheim: I'm sorry, Rhylian. But these samples...the exact strain of the virus in Nalaen's and Killian's blood is the same one that's in your blood. I suspect you contracted the disease long ago, certainly before you left Sanae. But instead of suffering the sickness that affects instead became an infectious, symptomless carrier. And I can see in your eyes that you've suspected it yourself for some time, but have been too afraid to face the truth.

    Western Animation 
  • Parodied in the South Park episode "Pink Eye," where Kenny's case of being a zombie was misdiagnosed as conjunctivitis. He goes through the episode without anyone (except Chef, eventually) noticing that he's causing the "pink eye" epidemic.
  • In The Powerpuff Girls, the Amoeba Boys catch a cold and accidentally cause a city-wide epidemic when the virus mutates within their bodies. Although they are villains (or at least try to be), they did not spread the cold on purpose, and so are this instead of plague masters.

    Real Life 
  • The Trope Namer: Mary Mallon spent nearly thirty years in forcible quarantine at North Brother Island, New York. Live typhoid bacteria were found in her gall bladder after her death. After she first became aware that she was infected with typhoid she was released on one condition: that she never return to her previous occupation as a chef. Five years later, and under an alias, she was doing just that. This led to her permanent lockup until her death. This was unusual in that other repeat offenders, including other food handlers and people who had more outbreaks to their name than her got off with nary a reprimand and a promise not to do it again.

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