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Anime and Manga
- In Birdy the Mighty, most Altans live in a slummy area of the city, called simply "the Altan district."
- In the Holy Britannian Empire of the Code Geass universe, the "Concession" cities in the conquered "Area" colonies are usually split between the rich "Settlements" inhabited by Britannians, Honorary Britannians, and generally the rich and powerful, whilst the "Ghettos" are where the conquered "Numbers" (conquered subjects), terrorists, and other unsavoury groups are forced to reside. The Tokyo Concession in Area 11 (Japan) is the best example, being the setting for the majority of the series.
- The city of Kumersun in Spice and Wolf has an area surrounded by high wall, where live alchemists and other people, whose profession is considered “suspicious” by the Church. Dina is a local chronicler, collecting tales not yet censored by authorities and mediating in trade between inhabitants and outside world. She also happens to be a giant bird, who took on human shape like Holo.
- Ceres in Ai no Kusabi.
- The world of One Piece is mostly populated by humans, while other species live in specific home islands. Giants work occasionally for the World Government, and fishmen and merfolk are known to marry other species, but it's extremely rare to see races like longlegs or dwarves wandering among humans. Separation seems to emerge naturally due to Fantastic Racism; the World Government doesn't enforce segregation but doesn't try to prevent it either.
- Living separated from humans on the sea floor is especially problematic for merfolk and fishmen. They don't need sunlight and oxygen, but they still yearn for it. However, the cruelty of humans makes them afraid of living above the surface.
- In Strontium Dog, mutant populations in New Britain are not allowed to hold any jobs (apart from bounty hunting) or live amongst normal humans, instead living in their own trashed ghettos, the most prominent one located in Milton Keynes.
- This shows up during Alan Moore's run on WildC.A.T.s, when the team visits Khera, where it turns out the Kherubim-Daemonite war ended centuries ago everywhere except Earth. Khera is ruled by the wealthy and technologically advanced Kherubim while the planet's indigenous population, a race of Sizeshifters from which Maul descended, has been displaced into underground cities, and Daemonite civilians living on Khera are confined to a low-tech ghetto. Having one Daemonite ancestor is enough to get Voodoo, a Kherubim-human hybrid like her teammates, forced into the ghetto.
- Top 10 is about an entire city where superheroes were relocated after World War II. There are separate slums for various other science beings like robots and vampires, and a throwaway line mentions Kaiju being confined to a tiny island.
- The X-Men family of books have given us multiple takes on the idea of a mutant ghetto, from concentration camps (Neverland), to reservations (the grounds of Xavier's school during the 198 series), to isolationist compounds (Utopia), to ethnic neighborhoods (Mutant Town/District X), to national "homelands" (Genosha).
- Marvel Comics also has Attilan, where pretty much every Inhuman on Earth lived (until it moved to the moon), and Wundagore Mountain, home of a society of humanoid animals.
- DC Comics has Gorilla City, a city in Africa populated by talking gorillas(!) and surrounded by a field that doesn't just keep humans out, it makes the city invisible!
- Both Marvel and DC have had periods where their respective versions of Atlantis were destroyed, leaving Atlanteans as refugees living in various aquatic shanty towns.
- "The League of Extraordinary Gentlemen": Volume III implies that these exist for aliens from Venus as "Treens Out" can be seen written in graffiti a couple of times.
Film - Animated
- The plot of the first Shrek movie was basically driven by the local Feudal Overlord turning Shrek's swamp-home into a ghetto for fairy-tale creatures and the like, and Shrek objecting rather violently to this - not so much because he's against ghettoization, but because he's against ghettoization in his back yard.
Film - Live Action
- Several in New Crobuzon on Perdido Street Station for pretty much any non-human sentient species.
- The Dipple on the planet Korwar in Andre Norton's science fiction stories. It was filled with war refugees no one wanted to deal with.
- The Wild Cards novels have Jokertown, the only place where Jokers (the 9 percent of the people who contract the Wild Card Virus who don't die or become normal-looking superhumans) don't have to be self conscious about their disfiguring mutations.
- The Orphan's Tales has Shadukiam city, where magical beings are either locked in separated areas on the outskirts (genies, one-legged) or forced to wear distinctive clothes (Yi). The local Mad Oracle (who actually pretends to be mad to scare off wealthy idiots) chose to reside in the shadow of the shiny basilica, chained to dirty wall, because it’s where those in need appear. Citizens prefer to have them all where they can’t dirty their beautiful city.
- In the Harry Potter books, there is a werewolf ghetto, which Lupin visits in Half-Blood Prince to tell them to Stop Being Stereotypical.
- In the old Star Wars expanded universe, non-humans on the Imperial capital world of Coruscant were relocated to a section of the City Planet officially called the "Alien Protection Zone," and colloquially known as the "Invisible Sector" or "Invisec." The locals are frequently harassed by stormtroopers, and in the X-Wing Series novel Wedge's Gamble, General Evir Derricote is kidnapping its denizens as test subjects to perfect his Krytos virus
- In Discworld Ankh-Morpork has a dwarf neighbourhood around Cable Street, and a troll neighbourhood around Quarry Lane. People like "Mayonnaise" Quirke sometimes refer to the dwarf district as "Tinytown". Snuff reveals that the goblin district is a shantytown outside the city walls.
- In Holly Black's The Coldest Girl in Coldtown vampires are trapped in ghettos called Coldtowns. Humans go into the Coldtowns to party.
- In the Dred Chronicles, the lawless Prison Ship setting is divided into various gang territories. Most prisoners aboard Perdition are human, but those who are aliens keep to themselves in their own isolated section of the ship, both avoiding other prisoners and being avoided themselves.
- Skulduggery Pleasant: There are mage-only neighbourhoods that are designed to look like ghettos so that Muggles will leave them alone.
- There's also a tower block that's controlled by vampires. The human residents give them blood in exchange for them keeping the area free from criminals.
- The Dan Shamble Zombie PI novels are largely set in the Unnatural Quarter, a slum district in an unspecified American city that's been zoned for habitation by the Monster Mash of non-humans unleashed by the Big Uneasy.
Live Action TV
- In E4's series The Aliens has a similar set up to District 9 with alien refugees living in a slum called Troy behind a gigantic concrete wall. They get let out during the day for work release though.
- Misfits: The Wertham Estate can be seen as an inversion of this trope. It was a normal borough of London until a mysterious storm gave a lot of the residents superpowers.
- In Shadowrun, Orks and Trolls often get this treatment. Notable examples include Orkland in the Bay Area and Yomi Island in Japan. Also, the Seattle Underground.
- In Traveller the Imperial Starport on each planet is a distinct place with it's own laws. This is less because of Fantastic Racism and more an application of the policy of compromise between Imperial hegemony and local autonomy.
- Some progressive worlds in Warhammer 40,000 allow mutants to live in miserable ghettos to serve as slave labor for the Imperium's factories, with only occasional pogroms to keep the numbers manageable. Other planets simply burn their mutants at the stake with the other heretics.
- The Alienages in the Dragon Age universe are ghettos for the City Elves. The "protective" aspect is brought up in a codex entry in the first game, in that it's technically legal to live outside them but elves who do nearly always end up being driven back in by their violently bigoted neighbors.
- The Magical Ghetto in Dreamfall: The Longest Journey is where The Empire of Azadi keeps the non-human citizens of Marcuria permanently locked in. Azadi claims it's for their own protection. It doesn't stop them from scouring non-humans' houses in search of illegal goods and blocking supplies of medicines and food to the ghetto.
- Anyone who uses magic is put in the ghetto, even if he or she is human. Roper Klacks, a human alchemist, is found there, despite the fact that alchemists don't have any natural magic abilities.
- Between Warcraft II and III, the orcs were confined to internment camps scattered across Lordaeron after being defeated in the Second War.
- You can visit some of these camps in World of Warcraft - one is in ruins and occupied by bandits, another has been reclaimed as the Horde's main outpost in the Arathi Highlands. Then in the Cataclysm expansion, the newly-promoted Warchief Garrosh confines Orgrimmar's troll and goblin populations to a cramped stretch of canyon, a situation made even worse when the goblins decided to drill for oil in the only water source.
- Touhou Chireiden ~ Subterranean Animism takes place in the Underground, home to a population of banished youkai like a plague-manipulating tsuchigumo or mind-reading satori, whose powers made them shunned and despised even by other youkai. There's also a lot of oni found there too, but oddly enough the oni relocated later and voluntarily, after getting fed up with humans resorting to trickery to defeat them. True to the nature of Touhou, the Underground's denizens seem far more content amongst their fellow exiles than they were before.
- Oddly enough the trope gets flipped around when you look at Gensokyo proper, where it's the humans who are confined to a single settlement, the imaginatively-named Human Village. There aren't any youkai soldiers or anything making sure the humans stay put there, it's just that there's an understanding that any humans encountered outside this village at night are fair game. Humans who live outside its borders tend to be people like Reimu Hakurei or Marisa Kirisame, who have repeatedly proven that they can handle themselves.
- In The Elder Scrolls V: Skyrim, the city of Windhelm segregates Dark Elves into the Grey Quarter, since the government of the city isn't too big on non-Nords, and Dark Elves and Nords don't get along. And they still get better treatment than the Argonians, who are locked outside the city walls and forced to live on the docks as woefully underpaid manual laborers and killed on sight if they try to enter the city proper.
- Likewise, in The Witcher, nonhumans are confined to dank slums on the west end of the city.
- Taris in Knights of the Old Republic has two. Nonhumans are ghettoed in the middle levels of the City Planet, while criminals are punished by exile to the planet surface, which is infested with rakghouls.
- In Final Fantasy XII, the natural inhabitants of Rabanastre have been forced by The Empire to live in what used to be the sewers of the city, while the wealthy and imperial citizenry take everything above the surface.
- Attempted in the backstory of RWBY, when humans attempted to relocate Faunus to the isle of Menagerie. The two sides eventually went to war and the end result allowed Faunus to live among humans, and while there's no institutionalized racism, there is still a lot of bad blood between the two groups.
- On Futurama, mutants (except for Leela) are legally required to live in the sewers underground. This changes in the season 6 episode (also the 100th episode) "The Mutants Are Revolting."
- Also, after the Native Martians sold their entire planet's surface to humans they were required to live underground. This is resolved when they discover that they sold their land for a gem worth a lot of money, allowing them to just buy a new planet.
- New New York also has Little Bitaly and Little Naptune, ethnic areas for robots and aliens respectively.
- The Simpsons: In Treehouse of Horror XXI, Lisa and Edmund run away to Dracula-la Land, a vampire neighbourhood inhabited by vampires from from different TV shows and movies.
- In Holidays of Future Passed, Bart drives by District 9, then goes buy District 10, a more upscale neighbourhood filled with Prawns.