Apocalypse How: Quite a few, but most famously the one that actually stuck, wherein minus resurrected the entire population of Earth, past and present, human and otherwise. It was crowded, to put it mildly.
A Wizard Did It: Since minus's powers are, literally, whatever she wants, "minus did it" is a perfectly valid solution to any Fridge Logic.
Back from the Dead: Everyone. This brings about the beginning of the end.
Be Careful What You Wish For: Rule of thumb: never ask minus anything when she's distracted, and always remember to be precise, and think of the side-effects before you do.
"Fool ! Do you think you can withstand the power of the Black Knight ?"
Body Horror: minus turns a balloon selling guy into a balloon himself when he yells at her for popping all his balloons. Then he pops.
Bittersweet Ending: The entire human race is destroyed, but lives on in the after life. Also, minus and the green haired girl look distinctly melancholy in the final strip.
Subverted when you remember that minus still has her godly powers and, ergo, can change the world back to how it was and do anything else to no longer be sad or melancholy.
Call Back: Sergeant Davy and his trusty steed, Prendon, are mentioned as having existed in the comic's world several strips after minus altered history to make Davy a war hero.
Characterization Marches On: Despite, as can be told by most of the rest of this page, having a reputation for being dangerous, in truth, all things considered, minus' stops doing more negative things very quickly - by halfway through the comic she's almost entirely neutral: only doing negative things out of naivete rather than intentionally doing them, and she often adds things to her some of the less positive things she caused to make them bittersweet or even good. She never stops callously making synthetic sentient beings, however.
Deus ex Machina: an in-universe version in minus herself, who tends to solve any problems or requests with a somewhat tangential application of her powers. Anyone who doesn't know about minus is usually some form of terrified or curious at the seemingly illogical and irrational things that occur around her (that tend to really be... well... illogical).
Granted, his actions cause a chain of events which directly lead to The End of the World as We Know It, so one could say that his retribution was delayed, but there.
The green-haired girl also pulls this off, accidentally.
Kids Are Cruel: minus doesn't generally doesn't recognize the consequences of their actions until they're presented to her, if they ever are at all. This leads to a lot of Disproportionate Retribution such as turning a man into a balloon and letting him pop, or moments like the creation of a miniature civilization in her tub only to destroy it when bathtime ends.
Seinfeld Is Unfunny: In-Universe: After the End, the ghost population finds the fact they had legs kinda funny, despite the fact most of them had legs before.
Shout Out: Various references to anime here. In order of lines, the immortal who wants to be human is from Soul Hunter, the second one sounds vaguely like a quote about immortality from Galaxy Express 999, the one about the witch giving up her powers is Magical DoReMi, and the quote about everything coming easy sounds similar to a lament made in Magic User's Club by Takeo's gay friend.
The Slow Path: #25 and #26. Slight subversion as she wouldn't make it back at all; minus brings her back in her old age to say good bye.
The then apparently retroactively sends her sister back in time with her, so they could live life together.
What Could Have Been: Strip #10 was the first one actually drawn, and at the time the creator had not yet decided whether minus would actually be all-powerful or just a shape-shifter. If he had chosen differently, the comic would have turned out very different.
You Gotta Have Blue Hair: And Green hair, and red hair, depending on minus' mood it seems. Some of the normal characters have green or red hair regardless of minus.