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Anime and Manga
- These are the most recognizable feature of Reine Murasame in Date A Live. She says she has had insomnia for 30 years.
- L from Death Note has these constantly. He's an insomniac.
- Another character who has these constantly is Miranda in D.Gray-Man, who suffers from insomnia due to anxiety and low self-esteem. In later chapters, though, she's less tired-looking and doesn't have eye bags.
- She still has noticeably thicker eye lines than most other characters in the series.
- In Soul Eater, Dr.Franken Stein acquires these after Asura is released. This is meant to show how the madness is wearing on him for a while before he snaps.
- Hayate Gekko from Naruto has these. This feature and his unexplained chronic coughing fits would suggest some sort of illness, but nothing has been officially disclosed.
- The thick black lines around Gaara's eyes are representative of these. He's possessed by a type of demon that torments people in their sleep, so he's naturally an extreme insomniac. This has more than a little to do with his very unbalanced mental state.
- In episode 5 of Kono Naka ni Hitori, Imouto ga Iru!, Shougo Mikadono's sister keeps calling him around 6am every day for a week, which causes him to be sleep deprived at school. Then episode 6 reveals that it was Mei Sagara calling him, pretending to be his sister, to keep him from finding out who she really is, lest his father's company publicly scorns and shame his illegitimate daughter and Shougo's half-sister, once her identity is revealed.
- Shown on the three Wannabe Toudai Students in Love Hina after they pull all-nighters. Naru has the eyebags, Keitaro tops it by having them and being wobbly all over... and Mutsumi subverts it, as she looks fresh and relaxed, despite not getting a wink of sleep.
- From Anpanman the Donburiman Trio get these in the episode Donburiman Trio and the Mysterious Forest. After being entranced so much by the charms of the princess from said forest that they pull all-nighters for her, the princess actually being Dokinchan in disguise to get free donburi out of them, they have dark purple patches under their eyes.
- The main character of No Matter How I Look at It, It's You Guys' Fault I'm Not Popular! has a notable case of these. Strangely enough, she's the kind who would stay up all night playing games, but they seem partially genetic: the rest of her family also have noticeably baggy eyes.
- Harumi Kiyama from A Certain Scientific Railgun has these, but we have a flashback that shows her both before she got them and the very moment she developed them. The Academy City leaders are bastards.
- Kuro from Servamp always has them, probably to show that he's a Lazy Bum who's always sleepy.
- In Attack on Titan, Eren has some in episode 15 after being forced to stay up all night listening to Hange explain to him everything she knew regarding Titans. She did warn him it would take a while before starting however.
- Verity Price from Discount Armageddon has to apply copious amounts of foundation to cover her exhausted eye bags from a too-nocturnal existence.
- The image appears a few times in the Aunt Dimity series, when a character is tired due to stress. To cite only one example, new mother of twins Lori is described with "her brown eyes smudged with bruises of fatigue".
- On Horton Hatches the Egg, Mazie complains of having bags under her eyes. In the Looney Tunes version, she has actual travelling bags under her eyes.
- In Harry Potter and the Prisoner of Azkaban, Hermione is described as having shadows under her eyes to rival those of the constantly ill-looking Professor Lupin when she pulls a few too many time travel aided all-nighters in preparation for her exams.
Live Action TV
- In The BBC's Based on a True Story drama We'll Take Manhattan model Jean Shrimpton gets these during her eponymous New York City photoshoot and has to wear sunglasses for part of it. This is either because she's tired and jet lagged, or because she spends every night bonking the photographer, David Bailey.
- Noises Off: Timothy Allgood, the stage manager, is verbally abused and horrendously overworked to the point of complete exhaustion by Lloyd Dallas, the in-over-his-head director of the play "Nothing On," which is nowhere close to being ready to present to an audience despite the premiere showing being just hours away. Keep in mind Allgood hasn't slept in nearly two days. For instance, when several props are not working properly (a window pane in a door keeps falling out; several doors are locked, etc.), Dallas — ignoring the pleas of the cast — barks at Allgood to make the repairs or else. He also tells Allgood he had better be ready at a moment's notice in case the unreliable actor Selsdon fails to show up or the neurotic Freddy passes out from whatever illness.
- Video Game/Touhou: Patchouli Knowledge occasionally sports these.
- Blake Belladonna from RWBY sports these because she's unable to sleep or eat from stressing over the White Fang and Torchwick's plans.
- In Destroyer of Light Persephone sports those all the time, as does Hades. It is part of their gothic persona, implying that they're mainly up at night, if they can choose.
- Manly Guys Doing Manly Things: After a wild Halloween party, hung-over Commander Badass and Jonesy are seen sporting these.
- Questionable Content: When he's having an existential crisis, Pintsize (being a robot) draws bags under his eyes with a dry-erase marker.
- Life: Five days into her twenty-day mission to complete a portfolio for the graphic design major at college, Felicia develops an impressive pair of these.
- In El Goonish Shive, Tedd has these after a bad night of sleep due to bad dreams.
- In Girl Genius, Gil abuses Skifandrian mental exercises designed to help people stay awake for a few days at a time in order to stay awake for two and a half years. It shows.
- Katie's Author Avatar in Awkward Zombie has these.
- In Avatar: The Last Airbender Aang, Katara, Sokka and Toph all have bags under their eyes when they go without sleep due to being chased for days by Azula and her Quirky Miniboss Squad. Later Aang gets this when he goes three days without sleeping due to nightmares of the coming battle.
- Naturally, Tex Avery exaggerates in the cartoon "Doggone Tired" with the characters having bag upon bag piled under their eyes, running down all the way to their cheeks.
- Similarly to the Tex Avery example above, in the SpongeBob SquarePants episode, "Fear of a Krabby Patty", Mr. Krabs forces Spongebob and Squidward to work at the Krusty Krab non-stop. At one point Squidward exclaims, "Look at these bags under my eyes! Even my bags have bags!" We are then treated to a Gross-Up Close-Up of Squidward's eyes.
- In My Little Pony: Friendship Is Magic, Applejack gets those when she is badly overworked with apple harvest (and too stubborn to accept help)
- Taken to an extreme in The Angry Beavers when the characters stay awake for a "bah-zillion" years
- An episode of Family Guy parodied celebrities who looked like this by having Ashley Judd and Vince Vaughn in a fake TV show entitled People Who Always Look Really Tired, drawing attention to the bags under the celebrities' eyes.
- In Fairly OddParents, Timmy makes a wish where no one had to sleep, and everyone in Dimmsdale had bags under their eyes from fatigue, and various other Gross-Up Close-Up aliments coming from not sleeping.
- In "Birthday Battle", Chloe gets these when she stays up all night setting her up birthday party.
- In Ultimate Spider-Man Peter suffers these as a result of being sick and not getting enough rest due to wall crawling heroics.
- All the contestants in the Total Drama Island episode "The big Sleep" develop these as a result of the challenge being who can go the longest without sleep.
- The Ren & Stimpy Show: Ren gets some truly epic ones in episode "Space Madness."
- Rocko's Modern Life: Rocko gets them after working overtime at work, to the point where they hit the floor.
- Stu gets these in The Rugrats Movie after Dil's crying is keeping him awake.
- Lex Luthor develops these in the Superman: The Animated Series episode "Ghost In The Machine" after Brainiac kidnaps him and forces him to repair him for weeks, Lex is horrified when he discovers he has them.
- Magee from the Prep and Landing specials has these. They become more noticeable in stressful situations.
- One episode of Sonic Boom has Sonic himself sporting these. He even sleep-slides through a laser fence as a result of his fatigue. *
- Dipper Pines from Gravity Falls always has these. He likes to stay up late reading.
- In the episode "Sock Opera", this is taken one step further when he stays up all night trying to figure out the password to a laptop.
- Lincoln Loud from The Loud House has bags and discolored eyelids, probably from constantly dealing with the antics of his ten sisters.
- Homer Simpson gets these, along with pink bloodshot eyes, whenever he gets a hangover from a hard night of drinking.
- News reporter Joan Grody from Teenage Mutant Ninja Turtles (2012) always has them.