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Especially Zoidberg refers to when one character makes an absolute statement, to which another character replies, "Even X?" The inevitable response will be "Especially X."
Sometimes X can be an obvious exception, and sometimes X can be someone of great importance to the character who asks about them. In the second case, it is typically the villain who gloats, "Especially Fred/ Your Mom /Mr. Chuckles."
Compare and contrast My Friends... and Zoidberg.
Keroro, drunk on humidity, orders the destruction of all Pekoponians Giroro: You want to kill them all? Even that shy, awkward boy [Fuyuki]? Keroro: Especially that shy, awkward boy! Giroro: But sir! That's not what you said before the commercial break!
Saddam Hussein: Before I took over Kuwait in 1990, I meet American ambassador, I say, "You got a problem with this?" She say, "We have no opinion on your Arab-Arab conflicts". Krishnan Guru-Murthy: Even Kuwait? Saddam Hussein: Especially Kuwait. They said so specifically. So I invade Kuwait, and Oy Gewalt.
Annabelle Farrell: Nothing personal, Shane, but I don't date football players. Shane Falco: I don't blame you. Not even quarterbacks? Annabelle Farrell: Especially not quarterbacks. You guys are the biggest babies of all.
Dr. Dakota Block: And if anyone comes to the door that isn't me, I want you to shoot them. Okay? I'm not kidding, Tony, you shoot them in the head. Tony Block: What if it's Dad? Dr. Dakota Block:Especially if it's your dad.
Captain Miller: We all have orders, and we have to follow 'em. That supersedes everything, including your mothers. Private Reiben: Even if you think the mission's FUBAR, sir? Captain Miller:Especially if you think the mission's FUBAR.
De Georgio: Ah, that's one thing about our Harry, doesn't play any favorites! Harry hates everybody: Limeys, Micks, Hebes, Fat Dagos, Niggers, Honkies, Chinks, you name it. Gonzales: How does he feel about Mexicans? De Georgio: Ask him. Harry Callahan: Especially Spics.
Frasier: You refused to take me to see "West Side Story" on my eighth birthday. Martin: Well, because of the gangs. That's scary for kids. Frasier: Even gangs that dance? Martin: Especially gangs that dance!
Terri Coverley: Do they all hate it? The Times? Malcolm Tucker: Especially The Times.
Friends: Joey has found an engagement ring in Ross' bag and when Joey picks it up, Rachel thinks he's proposing and says yes. Phoebe knows about the ring and so, when Rachel brings up that she's engaged, she assumes Ross proposed. This leads to this conversation:
Phoebe: Everyone has been waiting for you two to get together. Rachel: Really? Even Ross? Phoebe: ...especially Ross!
Buffy: Ah... Film Club. Xander: They spend their time deciding that every movie is an existential meditation on Freudian sexuality. Buffy: Even The Muppets Take Manhattan? Xander: Especially The Muppets Take Manhattan.
Earl: I'm not going to defend you anymore. And while we're at it, I'm not gonna kiss your boo-boos any more either, that's getting a little awkward. Randy: Even when we're alone? Earl: Especially when we're alone.
Castle and his daughter were watching a zombie movie at the start of the episode, but he gets called away on a plot hook. At the end of the episode, he's consoling her over her boy troubles.
Castle: When two people care about each other, really care about each other, anything is possible.
Alexis: (turning on the TV) Even flesh-eating zombies?
Castle:Especially flesh-eating zombies.
Murdoch Mysteries, episode "Who Killed the Electric Carriage?": Inspector Brackenreid finds out that his wife (who's been giving him a hard time about his drinking) and other ladies from Temperance League participate in bloody gambling, so he orders Constable Crabtree to arrest everybody in the bloody den.
Lackya: Master Gilgamesh! The baron demands you attend him - now! Gilgamesh: What? Lackya: Right now! Gilgamesh: But- Lackya: I have never seen him so angry! Gilgamesh: Um... with me? Lackya: Especially with you!
Least I Could Do: In Rayne's Alternate History novel where he kills Hitler and takes over the Third Reich, an assistant tells him that the Jews, Gypsies and mentally handicapped are asking for reparations. He tells the assistant to give each of them a tank.
Helen: Don't tell anyone about this. Artie: What about Mell? Helen: Especially Mell. Artie: Dave? Helen: Let's start over...
Note that Artie only has three people he can talk to at this point: Mell, Dave, and Helen herself.
Questionable Content briefly mentions J. Edward Runcible, an anti-European conspiracy theorist who tried to introduce legislation which would have "outlawed Europe as a continent, with special emphasis on the Swedes."
Schlock Mercenary: The discovery that his ship's AI is monitoring everything on the ship prompts Tagon to question "Even the showers?" To which the AI Petey predictably responds "Especially the showers." The AI is watching you in the shower, horror movie? Not this time.
Melvin: I have doomed you to exist in your own worst nightmare: a world where everyone's breasts are bigger than yours! Mai Valentine: Even Tristan's? Melvin: Especially Tristan's. Tristan: My briz-easts are off the hiz-ouse.
Croquet: Yeah... everyone involved with the production of the Egyptian God Cards was killed. Pegasus: What? Even Chad from accounting? [Cut to a man being thrown through a skyscraper window] Croquet:Especially Chad from accounting.
From the "We'll Be There" - Rex & Weevil video;
Rex: Everybody in this music video is a giant slut. Weevil: Whoa? Really? Even Yugi? Rex: Especially Yugi.
A Running Gag throughout "Leela's Homeworld" is how the sewer mutants keep on using the Leg Mutant as the most definitive example of a hideously mutated individual.
Mutant Doctor: In my professional opinion as an ear, ear, ear, nose and throat doctor, she is the least-mutated mutant ever born.
Morris: And yet she's cursed to live the horrible degrading life of a mutant. Like all of us. Especially him! [Points at the Leg Mutant].
Leg Mutant: It's true.
"Into the Wild Green Yonder":
Number 9 Guy: So dig this, Fry. Our commune's been monitoring the universe's life energy for, like, a really long time, and we're grokking some super-weird junk.
Fry: I don't mean to be rude, but it's hard to take you seriously when you say junk like "grok" and "junk".
Number 9 Guy: What about "commune"?
Fry: Especially "commune". Come on, it's the fate of the universe. Puff it up a little.
In one of the Bugs Bunny cartoons, Bugs finds that all the animals are running in terror from the Tasmanian Devil. He looks up "Tasmanian Devil" in an encyclopedia and finds a Long List of all the animals Devils like to eat. Bugs reads through the list, then says "What, no rabbits?" Taz tears off the page to reveal "And ESPECIALLY rabbits!"
Earthworm Jim had an exchange between Bob the Goldfish and a Genie. "Destroy the universe!" "What, even the good parts?!" "(annoyed) Especially the good parts!"
GIR [over the skool intercom] Greetings, children of Earth! This is your new school announcer. A special surprise mandatory field trip is happening for the following lucky children. Morla, Flan, Red Rocky, everyone in Ms. Bitters's class except for Zim. And especially Dib. All these children get to go to a special place made entirely of food.