- In the episode "Be My Baby", Roseanne is complaining about trying to get pregnant...
Roseanne: Oh, poor Dan. He has to sit here with me for two minutes and do nothing, while me and God create a life.
Dan: Maybe my sperms are just waiting for your egg to shut up.
- In the episode "Party Politics", D.J. starts skipping school, Darlene finds out, and to spite Roseanne who previously tried to get her and David back together doesn't tell her mother and helps D.J. by pretending to be her when the school calls. Roseanne becomes more and more annoyed as her attempts to get information out of D.J., Darlene and even David fail only to thwart the kids' plan in the final two minutes of the episode...
: (posing as Roseanne thinking the phone call is from the school)
Yes, this is Mrs. Conner. No he hasn't been able to make it he has been very sick. (Cut to Fred handing the phone over to Roseanne) Roseanne
: Don't mess with the master Darlene. You guys are in so much trouble I'm going to make you wish I was never born. Oh! And by the way, I know you and David made up too. Darlene
: How did you figure that out? Roseanne
: You just told me
! (hangs up phone)
- In "Crime and Punishment":
Jackie: What kind of obscene reading material did DJ have?
Roseanne: Well, either one of Dan's Playboys or our credit report.
- The episode "War and Peace" may be a moment of awesome for Dan as he beats up Jackie's abusive boyfriend, Fisher, but it has a lot of funny moments as well.
- Dan arrives home after beating up Fisher carrying a bucket of fried chicken. The following exchange is priceless:
Roseanne: Oh god! You didn't kill him and then buy chicken, did you?
Dan: Nah, I bought the chicken first.
Roseanne: Well, put some alcohol on that [his hand].
Dan: Good idea! (opens the fridge and takes out a beer)
- When Dan gets arrested for beating up Fisher, he agrees to go along quietly. But as he leaves, he says, "I'll drive."
- Roseanne puts a piece of fried chicken in Dan's mouth to eat on the way to jail, because he hadn't eaten dinner yet.
- Roseanne goes to the hospital with Jackie and sends Darlene to bail out her father. It goes about as well for Dan as you'd expect.
: Well, well, well... Dan
: Oh... man. Darlene
: My, my, my, my, my. Dan
: What are you doing here? Darlene
: You know I bet when you imagined us in this situation you always pictured yourself on the other side of those bars. Dan
: Where's your mom? Darlene
: Organizing the candlelight vigil. Dan
: Come on, Darlene, I don't have time for this! Darlene
: Oh, I think you do. Darlene
: She took aunt Jackie to the hospital, so I'm here to post bail. But I'm a minor so I have to give the money to the suspect... which I guess would be you. Dan
: Give me the money. Darlene
: Alright, but I want you to know it's coming out of your allowance. Dan
: Now! Darlene
: Prison's hardened you. Dan
: Now get in there and tell Ray to let me out of here. Darlene
: OK. By the way, I think it was a really cool thing you did. Dan
: Thanks. Darlene
: I guess I should prepare you for all the things that have changed since you've been in the big house... (short beat) Darlene
: Mom says we have a new daddy now.
- And the end credits scene, in which the police car is waiting at a light, and who should pull up next to them but DJ's teacher?
- In the last Thanksgiving episode, Bev goes on a huge anti-man tirade and accidentally reveals that she is a lesbian. Cue hilarious reactions from everyone at the dinner table and Darlene calmly snarks:
Darlene: Well, I think grandma just outed herself!
- This line becomes even funnier when you think about Sarah Gilbert's coming out as a lesbian.
- Leon's response is hilarious, too. "Welcome to the club. We'll teach you the secret handshake!"
- The trick Darlene, David, Becky, and Mark play on D.J. to make him think he's going insane.
- The episode "Home Ec", in which Roseanne is a guest speaker in Darlene's Home Economics class (much to her daughter's embarrassment), and takes the kids on a field trip to the supermarket to show them how one shops on a limited budget for a family of five, and explains the whole thing in a way that only Rosie can. The cornflake meatloaf (made with ground beef that was 50% fat) may seem disgusting, but many families on similarly limited budgets will be quite familiar with the concept.
- The episode where David gets a job at an amusement park. First, there's when Roseanne tells him why she's taking him away: "Five words, David — you're dressed like a rabbit." Then there's the "deprogramming" scene:
Roseanne: All right. Let's go over this one more time. Your name is David Healy. You frown, you're introspective, and you mope.
David: I'm not listening, I'm not listening, I'm not listening...
Roseanne: Listen to me, David! We don't whistle while we work! We grumble and complain and encourage others to do likewise!
David: Oh no, no, no, no!
Roseanne: Yes! Yes! Yes! Let me tell you a little something about your Edelweiss Gardens, David. It's mediocre food and mediocre fun at best. And you know why I know that David? 'Cause I am an expert on what is mediocre. [David starts breathing heavily through his teeth] That's good! You hate me now, don't you David? You're feeling hate. You hate me right now, don't you?
David: No, no, no I don't! You're a paying customer, and I respect and admire you!
Roseanne [slaps him]: Break, damn you!! Break! Listen to me, David! Rabbits and geese and goats are not people! They don't sing and dance! They're food!!
- David then breaks down in ridiculous sobbing as Roseanne holds him to her chest and says "Welcome home, son."
- The whole episode is a glorious Take That to ABC/Disney, after the network previously forced the producers to make what amounted to an infomercial for Disneyland.
- The episode when a competing diner opens across the street from The Lunch Box, and Roseanne plots ways to sabotage it.
DJ: [with [fake] blood pouring out of his mouth] There's glass in the salad!
Roseanne: Now don't waste all those capsules or you'll have to bite real glass.
- Roseanne and Jackie chasing down a sexist trucker.
- Roseanne letting loose on Arnold after he returns from abandoning Nancy and claiming he was abducted by aliens.
Roseanne: HOW could you tell Nancy that you were abducted by space aliens?! There's NOT EVEN A TWELVE-STEP PROGRAM FOR THAT!!!
- "Sherwood Schwartz: A Loving Tribute" features an extended fantasy sequence parodying Gilligan's Island. Jackie is Gilligan, Dan is the Skipper, Mark is the Professor, Darlene is Mary Ann, Leon and Bev are the Howells, and Roseanne is Ginger. And for some reason, David is there... and can't seem to find the basement. The end credits feature the surviving Gilligan cast playing the Roseanne characters in response... and David still wondering what's going on.
- In "What a Day for a Daydream":
Darlene: [David] thinks he's having pregnancy pains. Tell him that that's not possible.
Roseanne: Well, I don't know, Darlene. When my water broke, your father wet his pants.
- In "Couch Potatoes," Dan intends to fix the couch:
Dan: When I get done, it'll be as good as new.
Bev: This couch is pretty old and ratty. Why don't you just throw it out?
Dan: Well, around here we don't throw things out just cause they're old and ratty. I mean, hell, they could be old, ratty and annoying, and we'd still keep them around.
- Roseanne has two great lines in the same episode: first, when Dan accidentally breaks the couch. "Well, there goes that family of kittens." And later, when Bev gives her old couch to them. "It smells like Mom; it feels like Mom. It's like sitting on MOM!"
- In "Aliens", D.J. is participating in a spelling bee and his family is in attendance. When it comes down to just D.J., Dan prays that he gets a word that he knows. The teacher than says the word is "foreclosure". Cut to Roseanne and Dan smiling.
- In "April Fools Day", every time Jackie mentions the word "audit" dramatic background music plays, which Dan and Roseanne are able to hear but Jackie isn't. Every time the music plays the two look around to find out where it's coming from as if they're going crazy since Jackie doesn't hear anything, until a fearful Roseanne decides they need to get out of the house.
- This becomes a Brick Joke at the end when the word "audit" is mentioned, and Roseanne and Dan both expect the music to play. When they walk out the front door... DUN DUN DUUUUN!!!
- At the very end of "Bird is the Word", Roseanne leaves the principal's office at Becky's school and notices the secretary is gone. She picks up the intercom microphone and announces, "Attention, all students taking Latin: you're wasting your lives!" before runs off. Currently, this can only be seen on DVD as all syndicated edits of the episode end just before this part.
- Roseanne got to plan Leon's wedding in "December Bride" and turned into what Leon thought of as "every gay stereotype merged into one" including drag queens, pictures of Cher and Liza Minnelli everywhere, male strippers, and because they couldn't get a plastic figurine of two grooms for the cake, they settled for one of a groom and an action figure from Pocahontas.
- When Jackie is looking through a selection of male strippers to hire, D.J. looks at one of the catalogs and says "Cool!" Dan worriedly asks why D.J. would say that while looking at those pictures, and D.J. responded "because that one's my math teacher!"
- Leon gets cold feet and tries to leave through the bathroom window, when he gets stopped by Roseanne and the two get into an argument about Leon's pathetic reasons.
Leon: Scott says he is not himself in the morning until he has a Pop Tart. Well, what if they stop making Pop Tarts?!
Roseanne (over Leon's arguing): Leon, LEON, LISTEN TO ME. THEY WILL NEVER STOP MAKING POP TARTS!!!
- And then Leon says what if he isn't really gay at all.
- And the one thing that snaps Leon out of it? Kissing Roseanne.
Leon: I'm gay. Let's go.
- "The Fifties Show" was a potshot at 1950s sitcoms done in black-and-white and presented as the "lost pilot" to Roseanne. The episode opened with Roseanne in a recliner, drinking a glass of brandy and smoking a cigarette in a fancy holder, addressing the audience in a fancy speaking voice.
Roseanne: Good evening. My name is Roseanne Barr-Pentland-Arnold-Thomas, or as I like to call me, Roseanne. What you are about to see is the original Roseanne show pilot. It has been lost for some forty years, along with my mind. The difference is that this episode has been found. Love to all my fans. Enjoy.
- The scene then ends with Roseanne slowly pucking up her lips in an exaggerated way as she brings the cigarette holder to her mouth.
- The scene at the beginning of "PMS I Love You":
- Dan's explanation for why he didn't throw away Roseanne's old weed in "A Stash from the Past".
Dan: But as I watched it float helplessly, I thought to myself, "Am I really ready for this part of my life to be over?" The next thing I knew, I was down on my knees with your hair dryer and the aquarium net.
- And the end, after Dan and Roseannae have decided to go sober up:
Jackie: Hey, guys? I don't think this stuff's workin'...
- In the last Halloween episode, "Satan, Darling," Roseanne realizes that the names of Darlene's creepy neighbors are an anagram for "Evil Demon Satan."
: And look they also spell "Save Damien, Not L." And Damien was that horrible devil child from The Omen
: Who's L? Roseanne
: I dunno.
- And of course this just becomes hilarious when Death Note is added to the equation.
- The guest appearances of Edina and Patsy from Absolutely Fabulous.
- Patsy and Jackie both think the other's a guy, and then Patsy mentions she actually was for a year before "It dropped off."
- Edina tries to convince Roseanne to make her her publicist. When Roseanne says she has four kids, Edina says they have to get rid of at least two and will try to get Mia Farrow to adopt them.
- Edina saying they can clone Jackie O. ala Jurassic Park from blood on a used razor.
- Everybody proceeding to get drunker and drunker, leading up to Edina crawling into Roseanne's bathroom stall to negotiate with her before finally passing out during the credits. And no one notices or gives a shit. What makes it better is that the rest of the credits are just her on the floor before she finally wakes up.
- Roseanne's drunken rant defending Kathie Lee Gifford using child labor.
- The girls trying to wake up Roseanne after she passes out. When informed she had ten martinis and "that thing" Patsy gave her, Patsy immediately pulls out a funnel and suggests pumping her stomach. Edina tries slapping Roseanne awake before Jackie tells her to step aside... and punches her.
- While looking for Darlene in her satanist neighbors' apartment, Roseanne briefly stops to check out a framed painting of the design from the infamous chicken sweater, and looks very disturbed and unnerved by it.
- When first meeting the group of witches, they try to get her to drink a suspicious potion, but Roseanne says she'll only take it from "That witch!" Cue Marlo Thomas about to go through the opening credits of That Girl before she has to tell the background music to "Stop it!"
- Jackie tells their Auntie Barbara that their father has passed away.
- Much of the Season 3 episode "Like a Virgin," including the birth control talk, the entire scene when Roseanne catches Darlene and Brian making out on the couch, and the "sex talk" with both girls that follows.
- Roseanne and Jackie both trying to squeeze into the sleeper cab in Jackie's truck, which appears to be about two-thirds the width of a twin bed.
- The ending jokes are sometimes the funniest parts of the whole episode. Some memorable moments include Laurie Metcalf polishing her Emmy and Roseanne and John Goodman chasing her to try and steal it; Bruce Willis' surprise appearance; the Two Beckys parody of the Patti Duke credits, and Fabio.
- Meg Wellman is prone to Accidental Misnaming, such as calling Roseanne "Roxanne" and calling Jackie "Janet." One day, Roseanne introduces her to Dan by saying, "You know my husband, Don," then whispers to Dan, "Trust me." Sure enough, Meg replies with, "Of course! It's nice to see you, Dan!"
- Jackie spraying her mattress with disinfectant after she sleeps with Arnie. The look of disgust and resolution on her face is so strong, you can practically read the "I should just throw this out" thought bubble above her head.
- In one episode, David has a sex dream about Roseanne. Dan's reaction when he finds out?
Dan: (completely deadpan) Well I see no choice dear, you must give yourself to him.
- In "The Parenting Trap" DJ is having spontaneous erections at school and is embarrassed to go up to the board. Dan talks to him, but Roseanne doesn't like his solution ("Put a book in front of it"), so she sits DJ down for a heart to heart and tells him about when she got her first period. Cue DJ running screaming from the room!
Dan: "Whoa, whoa! What are you doing?"
DJ: "Mom just told me a story and I don't wanna hear it!"
Dan: "Well that's no reason to run screaming from the room!"
DJ: "It was about her period!"
Dan: "...As you were."
DJ: (running up the stairs)"AHHHH!!!!"