Films — Animation
- Brother Bear: Koda paints the painting in one of the vignettes during the credits.
Films — Live-Action
- Cameron stares at the painting during a Staggered Zoom shot in Ferris Bueller's Day Off.
- Looney Tunes: Back in Action (incorrectly) shows the painting in the Louvre.
Live-Action TV
- The cast of The Office (US) recreated the painting for a season seven promotional shot.
Theatre
- Sunday in the Park with George is in part about Georges Seurat painting this work after observing many people in the Parisian island.
Video Games
- It's a recurring painting (called the "Calm Painting") one can purchase in many Animal Crossing games.
Webcomics
- The September 20, 2021 strip of Square Root of Minus Garfield references the painting, since the second panel is done in a pointilist style and Garfield calls a mouse's grand jeté as a "Grande Jatte".
Western Animation
- Muppet Babies (2018): In "You Ought To Be In Pictures", Fozzie's lunchbox is stolen by the monkey in Grande Jatte, and he and the babies go into the painting to get it back.
- The Simpsons: In "Mom and Pop Art" Barney recreates the painting on a napkin.