These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Demonic Spiders: Hunter Betas. They aren't quite as hardy as their Alpha cousins, but they're twice as decap-happy and they don't always wait until you've hit "caution" before they swat off your noggin. They also have an infuriating habit of appearing in groups nearly EVERY TIME they're encountered and are damn near impossible to sneak up on, as you could often do with the RE 1 Hunters.
Ensemble Darkhorse: Nemesis is one of the series' longest standing popular monsters. He is highly regarded as the best thing about the game and for contributing a Paranoia Fuel feel to the game that was unlike the series ever had before.
Nicholai is surprisingly popular with a great deal of the fanbase as well. Sure he's a huge jerkass, but he's also deliciously Large Ham and extremely Russian. He also has the distinct honor of being like HUNK as the only surviving Umbrella operative.
Hilarious in Hindsight: A bit of an obscure one. In the Versus Books Perfect Guide for Resident Evil 3, the author as a joke, pointed out various similarities between Nemesis and Sagat from Street Fighter. At the end he hopes that "Street Fighter Vs Resident Evil happens someday soon!" Fast forward to 2011, Nemesis is one of the playable characters in Ultimate Marvel vs. Capcom 3.
Tear Jerker: The ending. Seeing Raccoon City being decimated with all those helpless people turned Zombies as Jill, Carlos and Barry Burton watch from their helicopter is absolutely heart-wrenching. Not to worry, it gets much worse. We are then treated to a still of a large mushroom cloud following the nuclear explosion as we are fed a news story informing us that other than Jill, Carlos, Leon, Claire, Sherry, Ada Wong, Barry Burton, HUNK, and Nicholai there were no survivors. Yep, all 100,000 people vanished. All while this heart crushing track is played in the background.
The diary entry of the mercenary found in the Clock Tower with the girl he was trying to protect. At the end, he says he wanted to do the right thing. He did.
After the fight at the Clock Tower with Nemesis, Carlos (if he didn't destroy Nemesis's rocket launcher) will appear and prove that He Really Can Act by begging Jill to wake up.
That One Boss: The fight with Nemesis at the Clock Tower is one of the toughest boss battles in the game. You have a very limited space in which to fight him in, and he will often knock you down, then pick you up and do a One-Hit Kill move. Plus, you can't see your health indicator anymore.
While there are tricks and tips available to beat him, Nemesis in general can be really nasty if one is going to slay him for the weapons. If only because he'll pick fights with you in hallways where you're at a disadvantage in fighting him.