One of Jill's extra costumes mimics Regina's appearance from Dino Crisis, which was developed concurrently.
The STAGLA gas station that is visited during gameplay has a DeLorean DMC-12 crashed out front, in a reference to Back to the Future.
The ending sequence involves a missile strike on the city in a sequence that greatly resembles the end of the first Return of the Living Dead.
When you reach the power station, you may get a Live Choice as to how to deal with an incoming zombie swarm. One option is to turn on the power to the exterior fence, which results in a sequence a lot like the ending of Return of the Living Dead Part II.
Speaking of Return of the Living Dead, we see zombies rising out of graves in this one, something the first film did to great effect (and while raining, to boot).
The game is a nigh on zombie take of The Terminator, with Nemesis as a near-indestructible monster who pursues an Action Girl through various urban environments, where Jill uses the series' signature weapons (minigun, handheld grenade launcher, Winchester 1887, AMT Hardballer) complete with a shotgun that she cocks one-handed.