Dr. Eggman: So let me get this straight... We team up to wreak havoc on our respective enemies. Dr. Wily: Yep. Dr. Eggman: We combine our intelligences to create powerful robots and unnecessarily complex schemes. Dr. Wily: That's right. Dr. Eggman: And in the end, everything will blow up in our faces. Dr. Wily: Probably. Dr. Eggman: So why are we doing this? Dr. Wily: You have anything better to do?
— Two Evil Scientist Villains Victorious, Pt 1
Two Evil Scientists is a long-running sprite comic that has been updated since 2004 and has enjoyed a somewhat more than modest fanfare. Initially starting out on keenspace (now comicgenesis) the comic was moved to smackjeeves where it became one of the longest running comics on the site. The comic takes a somewhat lighthearted idea and makes it work; pitting together the characters from both the Mega Man series and the Sonic the Hedgehog series. Rather than solely focusing on the exploits of the heroes of these series however, the comic, as its title implies, has a heavier focus on the two main villains (Dr. Albert Wily and Dr. Ivo Robotnik) from these series. The author makes use of the many similarities between these series to make for an interesting comic.The series is currently on an extended hiatus.
Or the fact that he built a fully functioning artificial penis for Mega Man X before he even finished the designs for his other systems. Did I mention that he keeps it in his pocket? Yeah, there's a reason he's a mad scientist.
Break the Cutie: Bass does this to Cream when she finds out he is, in fact, evil.
B Side Comics: The author, MC Ryan's Mega Girl (on hiatus, or dead) and Chrono Crossover (now ended) feature characters that have at one point appeared in the main comic but use storylines far different from the main comic.
Lolcats: Tango falls in love with Blaze. He wants to be able to communicate with her, so he has Auto reprogram him, leading to this.
Love Triangle: For a while, there was one with Amy, Mega Man, and Sonic. Quint's first role in the story was an attempt to remove Sonic from the equation, leaving nothing in between Amy and Mega Man.
Mad Scientist: In the current time alone, there's 5: Dr. Light, Dr. Wily, Dr. Eggman, Dr. Cossack, and Tails. Out of all of them, Dr. Light is the most disturbing.
Massive Multiplayer Crossover: Mostly done for kicks, but several of the comics imply that not only have Sonic and Mega Man been inhabiting the same world/universe, but Pokemon, Samus, and even other heroes inhabit the same world... the main focus, though, is always on the Sonic and Mega Man characters. Yeah...
Mauve Shirt: Hauser and Fairborne, the two G.U.N. Agents who went with Shadow, Rouge, and Vanilla to "rescue" Cream from Bass.
Meanwhile, in the Future: While Sonic and Mega Man are trapped in the future and past respectively, it keeps jumping back between them.
Mundane Utility: The titular scientists used two of their shapeshifting robots to pose as Amy and Roll and babysit for Wily's daughter Cream. This bites them in the ass later on when the two robots decide to betray them partly because of being used mundanely.
Nice Job Breaking It, Hero: Mega Hedgehog destroys the Master Emerald, the only thing powering Doppelganger's massive army. Too bad it was also the only thing preventing the Death Egg from crashing into the populated city below it.
The Not Secret: It's difficult for Mega Man to hide his identity from the rest of the cast.