Tien and Piccolo, after they stop beingtoken evil teammates, fill this role, respectively. Both are Goku's strongest non-evil ally at the time, coming the closest to matching The Hero 's battle prowess. Tien is a Type 3, then a Type 2, while Piccolo is a solid Type 3.
AKIRA has a rare female example in Chiyoko—she's well over six feet tall and carries a heavy machine gun everywhere. When she runs out of bullets, she'll happily bludgeon her enemies to death with a bazooka rocket. No bazooka, mind—just the rocket, used as a club.
Sanji from One Piece is the big guy for the Strawhat Pirates.
Black☆Star from Soul Eater, while not exactly big in size,DOES rely on force and his ego IS big,so . . .
Millie Thompson from Trigun is an example of the "Giantess" version of the Big Girl.
Rune Soldier Louie has Jeanie, who towers over her teammates and has a muscular physique that'd put most men to shame. She also has the type of strength you'd expect and could even trade punches with Louie when the two of them fought near the end of episode 12 (seen at 13:23-16:57, here).
From Beet the Vandel Buster: Bluezam, the wielder of the Boltic Axe in the hunting group 'The Zenon Warriors'. His status as 'the big guy' is emphasized when Beet is seen wielding the Boltic Axe for the first time. The weapon is so large and unwieldy (for the small Beet) that misses in combat tend to destroy walls, rocks and any teammates who might be nearby.
Milfa was shaping up to be this on Beet's team. She fights Vandels barehanded, throws powerful lightening attacks and is the highest level out of the Five-Man Band.
Satella in Chrono Crusade serves this role in the team (although Chrono probably would if his powers weren't normally sealed). Combining Class 1 with the Amazonian Beauty, Satella is the most powerful of the team because she's the most experienced, and a "jewel witch" that uses gems to summon servants to fight for her—including a large, knight-shaped crystal golem.
G-5 - Ryu "the Owl" Nakanishi from Gatchaman. Of the Class 2 variety. Though he actually isn't very tall, he is quite bulky and very strong (but not inhumanly so). He regularly employs sumo-like techniques in his fighting style.
Darker Than Black has several, generally one in each of its various organizations. On Hei's team, Huang is a quite good Class 3 example, being a gruff ex-cop who is a skilled sniper. On the Japanese police, Kirihara's second-in-command Saitou, who is a friendly, kind of bumbling guy who occasionally shows an impressive skills with firearms. Amagiri, Amber's Dragon has a Class 3 personality, being a generally pretty quiet guy who doesn't hurt people when he doesn't have to. When he does though, he can crush a person like an egg with his concussive force powers. Genma in the second season seems like a Class 4 at first, but he's really The Brute and a psycho.
The bad guys have a Big Guy of their own in Sloth, who even dwarfs Major Armstrong.
With the arrival of Saito in the Kyoto Arc, Sanosuke from Rurouni Kenshin becomes this. He's still considered Kenshin's partner in battle, but is a lot more power based than either Kenshin or Saito.
Mobile Fighter G Gundam has Argo Gulskii, a Class 5. He pilots the Bolt Gundam, a heavily armored machine employing brute strength, but uses that strength creatively and in one episode immediately sees through the enemy's diversion.