Mister Miracle gets a good one when he, as a child, escapes from the X-Pit in Justice League Unlimited.
Granny Goodness: You think you're so special, Scott. That you're different from Granny's other children. But you're not. If anything, you're just a little.. slower. You see, they learned years ago that their lives are meaningless, that hope is a lie. And you just figured it out. Scott: No. You're the liar. There's always hope. Granny Goodness: You'll never escape. Scott:Yes. I. Will!
"The use of words expressing something other than their literal intention! Now that! IS! Ironyyy!"
"NO! STOP! Take my hands! You evil! METAL! DOOOOORK!"
Garfield and Friends had the second opening, "We're Ready to Party", which was first enunciated as "We're! (We're!) Ready! (Ready!) To! (To!) PARTY!". Also, in the episode "Good Mousekeeping", Garfield is trying to nap while Jon keeps nagging him to get rid of the mice that have invaded. An exasperated Garfield eventually shouts "Let! Me! Sleep!" He still eventually has to catch the mice, though.
Bluestone from Gargoyles has a moment like this when he's determined to learn about the title characters from Elisa:
Elisa: You okay? Our shift's almost up and you haven't said three words all night. Matt:(quite deliberately) Let. Me. Drive.
The climax of "Amending Fences" plays this deadly seriously:
Moondancer: I never wanted to let myself be hurt like that again! Those three finally convinced me that I had value! That other ponies might like me and want to be my friend! And YOU! DIDN'T! SHOW! UP! [breaks down sobbing]
Another one has him drinking coffee, spitting it out and shouting "This. Is. Decaf!".
In fact, one episode featured four sketches with him shouting like that, playing at random times. Another one showed him at a party, informing other guests, "This. Is. MARTHA!!" and another had him eating dinner and proclaiming, "This. Is. SCRUMPTIOUS!"
"Breath! Short! Left arm! Numb! Can't go on ... describing symptoms much longer!"
The nurse from the episode of The Simpsons with the Hellfish treasure (punctuated with shotgun blasts:) OUR RESIDENTS! ARE TRYING! TO NAP!!!
From the same episode. "You. Are. DISMISSED."
And Mr. Burns in a Treehouse of Horror: "Bad corpse! Stop — scaring — Smithers!"
When Abe goes on a death race after promising not to, Homer: "Abraham J. Simpson.... You are never! driving! again! EVER!!!"
In another episode, Homer wouldn't let Grampa make a pit stop because he wanted to catch a TV special on F. Murray Abraham. When Grampa protested, Homer emphasized, "F! MURRAY! ABRAHAM!"
Afer Bart tricked Homer into eating fire and drinking lighter fluid. "WHYYYYY!!! YOOOOOU!!! LIIIIIITLLLLE!!!"
In the episode "A Streetcar Named Marge", Marge auditions for the part of Blanche Du Bois in Oh, Streetcar!, a musical version of A Streetcar Named Desire. After she fails her audition, Llewellyn Sinclair, the director, tells her that Blanche is supposed to be "a delicate flower being trampled by an uncouth lout". When he then sees a depressed Marge talking to Homer on the phone and agreeing to bring back some food for him, he grabs the phone and yells "Stop! Bothering! My! BLANCHE!"
"I warned her. DON'T...FUCK...WITH...WENDY...TESTABURGER!" (Scare Chord)
III'M! NOOOT! YOOOUUURR! FRIEEENND! BUDDYYYY!
"I....AM....SO....PISSED...OFF....RIGHT...NOWW!" From when Cartman sees that Stan and Kyle submitted a video of him having a tea party with his plush toys to a 'Funniest Home Videos' show. Followed with "I...AM...GOING...TO...* BEEP* ING...KILL...YOU...GUYS....SERIOUSLY!" and "HATE YOU GUYS...HATE...YOU...GUYS!!!"
Dey! Tuk! Er! Jeorbs!
I. Can't. Die.
My name. Is not. Mee-em. (Que Oh, Crap! face from Cartman)
In an episode of Spongebob Squarepants revolving around Pearl's birthday, Pearl gives her father Mr. Krabs a list of what she wants, but as expected, Mr. Krabs is too cheap to get any of it. Pearl winds up humiliated and yells at her dad:
"Daddy, how could you?! I! GAVE! YOU! A LIST!!!"
"MY NAME'S! NOT! RIIIICK!!!"
"Is this the Krusty Krab?" "No. This is Patrick." Another call "Is this the Krusty Krab?" "No This is Patrick!" Another Call "Is this the Krusty Krab?" "NO! THIS IS PATRICK!!!"
"What I learned in Boating school IS... BLANKETY. BLANKETY. BLANK!"
"YOU ONLY NEED THREE! MORE! WOOOOOORDS!"
And probably the best one, in "A Life in a Day". Spongebob: "THIS! IS! LIIIFE!"
Beast Wars: After Rattrap spends most of the two-part opener complaining, snarking at Optimus Primal, and outright refusing to obey orders, Optimus finally loses patience when Rattrap tries to shoot Dinobot for "attacking" Rhinox:
Optimus: Ease off, Rattrap. It was an accident. Rattrap: Says you! Optimus: That's right, says me! You wanna question my orders (jabs his finger into Rattrap's chest with each word) ONE. MORE. TIME?!
Later on at the end of Season II:
Optimus: "TIME! ITSELF! IS ALL! BEING! DESTROYED!" Megatron: "YES! The Decepticons win! Evil triumphs! And you! YOU! NO LONGER! EXIST!!"
After Inferno sets some plants on fire, Tigatron freaks the heck out and screams "YOU. WILL. LEAVE. THE WILD. ALONE!" and punctuates each word with a gunshot.