In Shuusou Gyoku's Extra Stage, when VIVIT encounters Marisa, Marisa's first line is "Shoot and I'll move!"
Marisa reprises the line when encountered in Reimu's storyline of Imperishable Night.
Marisa: Move and I'll shoot!
Marisa: I messed up. I mean, "shoot and I'll move". In a flash.
And at the end, after VIVIT defeats Reimu:
Reimu: Wow, you're strong... VIVIT: Well, will you listen to my request now? Reimu: Guess I've got no choice. ... what are you looking for? VIVIT: I have to find the "Holy Grail"! And I have to find it today. Reimu: ... what's that. VIVIT: You know, that special artifact that's said to have held the blood of the Christ after his crucifixion. Reimu: ... who's that? VIVIT: *sob sob sob*
Cirno in her first appearance:
Cirno: I'll cryo-freeze you along with some english beef!
Reimu vs. Chen in Perfect Cherry Blossom:
Chen: You can't leave once you wander in. Reimu: Is that so? By the way, I hear that Mayohiga's items bring you good fortune if you take them home. Chen: Yeah, that's true... Reimu:Then let the plundering begin! Chen: Uh... what!?
If the dialogue doesn't get you, Chen's face when she says the last line most likely will.
Same game, Sakuya vs. Alice:
Alice: So, for what reason do you worry? About yourself. Sakuya: Because I'm carrying only three changes of clothes. For myself. Alice: Ah, good reason. Sakuya: That, and a spare set of knives too. Alice: Ah, I— KNIVES?!
Quite a few bits of dialogue from the Touhou series in general are really amusing. Like this one from Imperishable Night against Reimu:
Alice: Why the stuttering? Just yell at her like you always do. Bitch, get out of the way! Like that. Marisa: No, don't! We'll be in for it if she gets mad!
From the same game, there's the choice between each branch, which really encapsulate Marisa's ("Go kick Eirin's ass! (Final A) / Blow up everything you can! (Final B)") and Youmu's ("Go where lady Yuyuko says (Final A) / Go where lady Yuyuko says (Final B)") personalities.
And again, Alice and Marisa, in Subterranean Animism:
Marisa: Whew... This is so hot. So hot I could die! Alice: (Are the dolls okay?) Marisa: Yeah, but it's so hot I wouldn't be surprised if they burned up. Alice: (I think the dolls themselves will be fine, but it would be bad if the gunpowder inside caught fire.) Marisa: Why the hell did you stuff gunpowder in 'em?!
The entire MAlice scenario in SA was just one hilarious line after another.
Satori: "Before that, let's search the house...." you think. I won't allow that. Please head to the courtyard immediately. Marisa: Damn!
Great Fairy Wars. Just about any conversation among the fairies:
Cirno: Huh, all of you really are here. Luna: The three of us are as one! Sunny: Though a single arrow is broken easily, if you bundle three together... Star: You'll run out of arrows three times as fast! :D
The fourth chapter of Strange and Bright Nature Deity. Two words: Stomach Cleaning.
This little show of, ehm, teamwork with Reimu and Yukari after beating Keine in Imperishable Night:
Keine: Tell me, where are you trying to go anyway? Reimu: That way. Yukari: This way. Keine: ... If you're after the ones behind the abnormal moon, it's that way. Reimu: Hah, I was right. Yukari: Reimu, your finger is off from hers by 70 degrees. Reimu: But you're off by 110...
There's also the dialogue in the Youmu and Yuyuko scenario:
Keine: There is nothing around here. Just move along already. Youmu: But honestly, we have no clue where we're headed. Keine: Are you wandering around without purpose? Yuyuko: No, no, Youmu. We're certainly heading in the right direction. All you need to do is follow me. Keine: What is your purpose? Youmu: To restore the corrupted moon. Yuyuko: No, no, Youmu. Youmu: Eh!? Yuyuko: It's a wonderful midnight snack tour across the land. Keine: You two are really suspicious. Even more suspicious than typical ghosts. Youmu: Wait, I can't just let you get away with saying that. Ghosts in general aren't suspicious. Yuyuko: No, no- Youmu: Shut up.
That's just her flying animation. Earth gods aren't very comfortable in the air.
Also the fact that up to this point, Sanae believed that she would end up fighting a Humongous Mecha, only to be disappointed when Suwako shows up, stating that the giant is just a useless doll made by the kappas to advertise her temple causing Sanae to demand they fight out of sheer annoyance.
Most spellcards are named after historical events or items, or supernatural phenomena. Then you get some that are blatantly a Take That against a character the user doesn't like, such as Reimu's "Exorcism of the Newspaper Subscription Solicitors", which consists of a GIANT seal saying "No News Solicitations! (Thank You)"note That means you, Aya. Bad girl., or Mamizou's "Pseudo-Exorcism of the Stupid Shrine Maiden", where she transforms into Reimu and spams her trademark homing bullets... while still having her Tanuki tail!
Marisa after fighting and insulting Futatsuiwa:
Mamizou: You... I shall have my revenge upon you! What is your name? Marisa: I'm Reimu Hakurei. Mamizou: Marisa Kirisame? I'll remember that. Marisa: Hey, go after the Miko, not me!
Even better, it's a Call Back to Marisa's EX stage run in Embodiment of Scarlet Devil. Flandre asks Marisa her name, and then later reveals that she heard everything that happened upstairs earlier in the game when Marisa tries to lie.
Flandre: Here I am. Marisa: And you are? Flandre: Before you ask someone else's name... Marisa: Oh, me? I'm Reimu Hakurei. A shrine maiden. Flandre: I am Flandre, miss Marisa. (There's no way you could be a shrine maiden.) Marisa: And who are you? (Maybe I should have said nurse?)
For that matter, the entire Ten Desires extra stage fight is this: Mamizou uses some of the most... interesting danmaku you'll ever see. See for yourself.
Miko's third card, where she summons Futo and Tojiko over and over to attack you while not doing a single thing herself. The best part is that Futo and Tojiko will eventually start complaining about it (instead of boasting or threatening you).
In Symposium of Post-mysticism, Miko talks about how Futo used to be scared of Buddhist statues, and responded by lighting them on fire.
Miko: And then before we knew it, the fire spread to the temple. We definitely went overboard that time... Marisa: Uh, that isn't really what you'd call cowardice. (sweatdrop) Byakuren: Maybe I should turn everything to stone for fireproofing. And make the statues stone, too...
Mamizou's last word in Hopeless Masquerade, since it has a lot of cartoony sound effects.
Her new spellcard in version 1.30 has her turning whoever she is facing into various animals with hilarious results.
In Miko's ending in Hopeless Masquerade, she manages to create a perfect Mask of Hope for Kokoro...which is a crude rendering of Miko's own face.
In the Wild and Horned Hermit manga, there's quite a number of funny moments:
ANYTHING involving the nameless Kitsune who transforms into Marisa.
"I don't think psychological attacks are weak against them" *Cue to an image bubble of Kanako, Suwako & Suika*
Never EVER PISS OFF Reimu. One of the Yamawaro tells Reimu to get lost since they're not bothering anyone. Sure this is considered a Crowning Moment Of Awesome but another Yamawaro looks at her with a shocked reaction thinking "Did you really say that to the shrine maiden?" At the end of the chapter, Reimu is still pissed and decides to go to war with them.
The hobgoblin learns the meaning of fear after staying at Gensokyo for a few days.
Anyone who drank the sake using Kasen's special drinking box.
Marisa: *carries Reimu* Look I can pick you up without breaking a sweat! *Cue to Reimu doing a Dive Kick at her*
Let's not forget what happens the next day where everyone who drinks using Kasen's special drinking box behaves like an oni.
Kasen happening upon Reimu and Byakuren about to have a duel. She starts loudly cheering for Reimu... before revealing that she bet against her.
"Reimu always screws up when she gets cocky. There's no safer bet."
The discussion of Gensokyo's energy policy in the second chapter. Made even funnier when you remember how ZUN usually draws inspiration.
Sanae: True nuclear fusion isn't meant to power hot springs. It's meant to be used to establish a self-sustaining energy source. Do you know where Gensokyo's energy comes from? Reimu: From getting your three square meals a day. Marisa: And booze. Sanae: =.=
How Kasen solves the problem when Reimu neglected her duties by doing fortune telling (Which is actually a huge success for her)? Enter Miko Kasen.