- Dear Negative Reader: Happened twice when Jory and Jon catered to fan requests. When the same base complained, the creators told them it was their own fault each time.
- The first was Episode #62 where the guys responded to the constant "Microwave a microwave" demands by using Sandra to microwave Diane's remains. This experiment killed Sandra and to make matters worse, they didn't have a backup microwave at the time of the episodes filming.
- The second and more blatant was Episode #189, made in response to fans complaining that their videos were overly long and had too much buildup to the microwaving segment. In response to the negative feedback, the guys pointed out the obvious: viewers can just skip to the microwaving at any time.
- Descended Creator: Jon Paula, series creator and cameraman, hosted six episodes.
- Long Runner: Ten seasons over four years (2007-11), with 300 experiments and slightly more episodes. Specials were sporadically made until 2015.
- The Other Darrin: Before there was Riley, Ryan and Ezra were the sidekicks.
- Referenced by...: The airbag episode inspired a background story in the novel Vasquez Private Eye, where a character was accused of murdering their father by microwaving an airbag.
- Throw It In!: The Don't Try This at Home warnings had one such instance. After recording one, Jory, Riley and Jon broke into the Oompa Looma song from Willy Wonka & the Chocolate Factory. The three all decided to incorporate that into one of their warnings.
- What Could Have Been:
- Back in season one, an entire episode involving Styrofoam (a block first, and two handfills of packing peanuts second) was filmed... but never properly aired because it was a boring episode.
- Background info reveals that the Orange experiment was going to have a cameo from The Annoying Orange, but that fell through.
- A minor one, originally Jory was going to microwave 16 CDs instead of 15note , but Jory used one to see if Sandra still worked after microwaving Diane (she didn't).
- Similarly, the Bubble Gum experiment was originally done with Helga... but it was discovered during filming that Helga actually broke from the "Fireworks" experiment.note
- The first three videos where Jory and Jon open up the donations they got reveal several experiment options that never came to be.note
Trivia / Is It a Good Idea to Microwave This?