In one of his Binding of Isaac: Rebirth streams, he tries to pull off a run with The Lost. After an hour of rerolling the first floor and repeatedly dying, he finally comes up with a build that works. What follows is ninety minutes of Slowbeef beating Binding of Isaac by standing still.
He beat Lt. Surge's Raichu with a Gyarados.
His Twitch subscription and donation notifications are voiced by David Hayter himself, with the lines done specifically for Slowbeef.
In the same vein, taking down the Spider Guardian on the first try, without even breaking a sweat.
The battle against the Caretaker Class Drone in Echoes has Slowbeef just barely eke out a win on his first try, despite starting the battle with more than half his health missing; even better, it is one of the few times in the Let's Play when he shows genuine excitement instead of just aggravation.
Creating one of the funniest running gags by simply asking, "If this game had voice acting, what would Ridley sound like?" The rest is history.