These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
The whole Sub vs. Dub debate is more pronounced than usual here, since the show is being aired in Japan AFTER America.
Cowboy Bebop and Outlaw Star fans who were expecting another serious sci-fi anime (with occasional comedy) in the same vein as those two were at least somewhat disappointed to learn that Space Dandy is more of an out and out comedy. Granted the show can have occasional serious moments (like the Pops scene in Episode 2) and some nice action scenes, but the overall tone is still outright comedic.
The above now seems to be slightly less broken as of post-Episode 5, with the show doing more of a balancing act between comedy and seriousness (see Growing the Beard below).
"Does Space Dandy have continuity or not?? If it does, they're not writing it clearly enough, and if it doesn't, that's not what anime should be like!" Fortunately, it turns out it does, and the writers intended to fool us all along.
Ensemble Darkhorse: During the initial launch of the show, Almost all of the fanart found on Pixiv was of Meow exclusively. Even though other characters are getting their own pics, Meow still has the most in general.
Meow's family from Episode 10. Only his mother and father get more extensive speaking lines, while at least three of his siblings (two younger brothers and a teenage sister) get small lines, but all of them are quite well liked by fans thanks to their cute appearances (of note, his teenage sisters are wearing Sailor Fukus, and one of the non-speaking siblings looks like a total Bookworm) and general likability.
While Space Dandy has a lot of one-shot characters, Adelie, Prince, Pine-Pine, and Johnny stand out the most. A lot of fans really want to see them return in future episodes.
Many of the alternate cast members from Episode 1 of Season 2, especially Emo Dandy.
The ending to Ground Hog Day Loop Episode 10, if taken literally rather than metaphorically, hints at a possible explanation to all of this: the crew might and have been stuck in a never ending time loop since the beginning of the show, due to the actions of the Gogol Empire's space warfare.
" Whether or not they're caught in a loop, they're still pretty much caught in a loop."
Evil Is Cool: Subverted to hell and back with Admiral Perry who has an insanely badass and sinister look but is actually just as incompetent as his mooks. It says something about your competence as a villain when you have the technology to casually blow up entire planets because you were being pestered over a used library book and yet you're losing the war your embroiled in.
Genius Bonus: Someone viewing "An Other-Dimensional Tale, Baby!" familiar with tesseracts will recognize Catherine as a 4th-dimensional being immediately. Her strange movements are of her turning around as would be perceived by 3-dimensional beings.
The phenomenon gestaltzerfall that happens to Dr. Gel is a result of staring at too many kanji characters for prolonged periods of time and forgetting their meanings altogether.
Growing the Beard: Episode 5, which was the first consistently serious episode in the series and showed Dandy having a Hidden Heart of Gold. Some see it as a step in the right direction since it shows the series isn't entirely a Gag Series.
Episode 4 showed how within the constraints of being said Gag Series, the anime still manages to pull one of the best laughs and storylines with its unique Slice of Life take on the Zombie Apocalypse trope.
Played for Laughs with the aliens in Episode 6, who insist that Dandy and Meow share a bed with them. One of the beds is even red and heart-shaped.
In-universe example after Prince falls for Dandy.
Slightly between Bea and Dr. Gel. Bea worries a lot when Dr. Gel appears to be buried in work, and Gel's final words upon being sucked into a black hole is "Hold me close, Bea!"
Hype Backlash: The show got a huge amount of hype, between its high production values and the fact that they went to the effort to have it air simultaneously in America (actually, the English version comes out a few hours earlier). As is always the case with this sort of thing, there are more than a few people who think it's not worth the excitement. Given that the hype heavily played up the fact that it was coming from the creator ofCowboy Bebop, a lot of people weren't expecting a Gag Series either.
Done again in Episode 3 where the end of the episode implies that Dandy forgot to save Meow. The scenes of the next episode show Meow is just fine.
Although there are hints throughout the show and the ending sequence that alternate universes are to blame.
Happens again in Episode 4, when everybody is zombified. Literally everybody, including the narrator.
Season 2 Episode 1 ending with All future episodes will be starring this (emo) Dandy. Complete with a redone title sequence.
Jerkass Woobie: Yeah Dr. Gel is a bad guy, but the sheer amount of times he gets blown up or otherwise horribly killed/abused makes it pretty hard not to feel for the guy. Not to mention he has probably the worst boss in existence in the form of Admiral Perry.
Nightmare Fuel: For a show that's often hilarious, the scene in Episode 3 where Mamitas sneaks up behind Meow who is distracted by the hologram Boobies card with the intent to eat him is rather creepy.
The first half of Episode 4. The second goes out of its way to undo this but manages to keep Meow looking downright horrifying.
Ugly Cute: The Plant Scientist's daughter, 0-33H, is ridiculously moe-worthy despite being a sentient plant. Her reactions with Dandy are just plain adorable.
The Woobie: Laika the lonely dog waiting for someone to love and play with her.
Adélie qualifies too. She was born without a father, her mother also died later in her life. She also spent the majority of the episode finding her grandfather, only to find out someone else has moved into his apartment. Just watching her break down sobbing after she accused Dandy of abandoning her makes you just wanna hug her.
Although he can be seen as a Butt Monkey, Meow is encroaching into the territory, if not borderline Jerkass Woobie. He was killed several times, lost a bowl of the best ramen in the universe, sobbed his eyes out over Laika's death, had insecurities about his home planet and had his heart broken by his childhood crush. The space cat could really use a hug.