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Video Game: Dr. Mario
"The pills Dr. Mario throws to destroy the viruses are in fact the major threat. The viruses in the bottle can never actually do any harm. In fact, it is the pills that can do harm, causing the player to lose the game if they obstruct the neck of the bottle. Thus Dr. Mario is, as a game, one about bad medicine."

Around the time of Tetris, Dr. Mario cashed in on both that puzzle game's fame and the fame of Mario, while providing an intelligent twist on both.

Mario in this game has changed from a plucky plumber to a determined doctor who has to destroy all of the viruses (red, yellow and blue ones). He uses a series of capsules to eliminate them (when four capsule pieces/viruses of the same color line up in a row).

Dr. Mario proved just as addictive as its puzzle game parent. "Fever" and "Chill", the game's two main themes, are almost as iconic as "Korobeiniki". Two other tunes, "Cough" and "Sneeze", have also been present since the N64 iteration.

The game made an appearance as a minigame in both WarioWare Inc.: Mega Microgame$ ("Dr. Wario", which is pretty much a sprite swap of the NES version) and Brain Age ("Virus Buster", which introduced touch controls to the series). Dr. Mario himself has showed up in Super Smash Bros. Melee, Super Smash Bros For WiiU/3DS, and the viruses appear as enemies in Mario & Luigi: Superstar Saga and Mario & Luigi: Dream Team.

This game has been on the following systems:


This series provides examples of:

  • An Ice Person: Chill, the Blue virus.
  • Ascended Extra: In most media outside the game, the Viruses are given their own powers and personalities relating to the sickness they instill. Two of them are also named after the tunes in the game, the other one being "Weird", the Yellow Virus. In the games, they're simply obstacles.
  • Canon Discontinuity: Not that Super Mario Bros. has much of a canon, but according to a 2012 interview with Shigeru Miyamoto, Mario's time as a doctor was "not necessarily legitimate".
  • Color-Coded for Your Convenience: It's a color-match puzzler, so...
  • Comic Book Adaptation: "The Doctor Is In... Over His Head" from the Nintendo Comics System explains to us how Mario got to be a doctor.
  • Continuity Nod: Not necessarily in this game, but all three viruses have been featured as enemies in the Mario and Luigi series.
    • In Superstar Saga they change into different viruses, an are taken out all at once when matched up. In addition they also power up another enemy called an Eeker.
    • In Bowser's Inside Story a Blue Virus is spat up by Toothies as an attack. They stab Bowser with a spear if they reach him in time.
    • Dream Team has them as enemies again, with the same matching color gimmick.
  • Dressed to Heal: The lab coat makes sense but there's not reason other than this trope for Dr Mario, who appears to work in pharmaceuticals, to wear a mirror and stethoscope.
  • Easy-Mode Mockery: In Dr. Mario 64, when playing Round 7 in Easy Mode, it's just you and the Hammer-Bot from Wario Land 3. But in higher difficulties, it's a free-for-all between the aforementioned, your rival, and Mad Scientists. You also can't face the Perfect Run Final Bosses in Easy Mode. Interestingly, Easy Mode also creates a case of What Happened to the Mouse? when playing as Wario in the opening for the final round, Dr. Mario is seen entering the castle after Wario, but doesn't show up again after that. In the higher difficulties, however, Dr. Mario just sits there dazed from the free-for-all battle as Wario enters the castle without him.
  • Falling Blocks: Well, falling pills.
  • Hospital Hottie: As seen in the manual for the game, Princess Peach is a nurse at whatever clinic Mario oversees.
  • Nintendo Hard: Good luck.
  • No Ending: The "Fever Clear," "Chill Clear," and "Game Over" songs go on for several seconds before abruptly cutting off.
  • Perfect Run Final Boss: Dr. Mario 64 has two. If you beat the game as either character, you face his rival, who has just ingested the megavitamins, resulting in either Metal (Dr.) Mario or Vampire Wario.
  • Shrunken Head: A commercial had a guy telling how he beat a witch doctor at the game, and got his head shrunk as a result.
  • With Lyrics: Of the background music.

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alternative title(s): Doctor Mario; Dr Mario; Doctor Mario
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