First Injury Reaction

Gaara: What is this?... it's so warm and...wet...
[A single drop of blood falls]
Gaara: [screams] BLOOD!! IT'S MY BLOOOOOD!!!!!

— Naruto

Oftentimes, when a character has spent much of their story unbothered and unharmed by any challenge or believes themselves to be beyond harm, lasting harm will bring great pause, accompanied by a lingering shot of their reaction. Even if they're not particularly tough, if they haven't been wounded before that moment and they stop what they're doing to react to this new, painful experience, that is also this trope.

Sub-trope of both Not So Invincible After All and First Time Feeling, where the act that proves the "invincible" person isn't draws blood or inflicts similarly visible injury, causing them to stop and react to its result; or the first thing the person feels is pain. A Cornered Rattlesnake finally lashing out against a seemingly Implacable Man can tend to be the cause.

Expect reactions to vary depending on the subject's personality, commonly This Cannot Be!, Oh, Crap!, Freak Out, or Tears of Fear for a Smug Super, Thin-Skinned Bully, Miles Gloriosus, or Paper Tiger; and Worthy Opponent for a Blood Knight or Spirited Competitor. A Drama Queen, a naive child, or someone very sheltered may think they're dying. This incident may lead to someone being Afraid of Blood.

Can overlap with Untouchable Until Tagged, if the hit that draws blood is the first successful attack and the "attacker" capitalizes on the time the "defender" wastes reacting to land another hit. May also lead to a Blood Upgrade in the inverse scenario where the "defender's" shock turns to rage. Compare First Blood, Minor Injury Overreaction, and Major Injury Underreaction.

Compare First Period Panic, when someone freaks out about a different kind of blood.

What Is This Feeling?, Is This What Anger Feels Like?, and My Eyes Are Leaking are the emotional variants of this trope. Sub-trope of Baffled by Own Biology.

While not always, this can be a Death Trope, so beware of unmarked spoilers.

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Examples:

Anime & Manga

• Cowboy Bebop: While fighting with Mad Pierrot at the abandoned amusement park, Spike throws a knife that hits Pierrot in the leg, wounding him. Up until that point, Pierrot had been completely invincible thanks to his psychic powers(?) protecting him from bullets and explosions, and the sudden shock of feeling pain for the first time in years reduced him to being unable to do anything beside roll on the ground screaming that it hurt. Unfortunately for him, he rolled right into the path of the park's animatronic mascot parade and was trampled to death by them.
• Dragon Ball Z:
  • During Goku and Vegeta's first battle in the Saiyan Saga, Goku manages to draw blood from Vegeta, who reacts with indignant fury at being wounded by a "low-class warrior", unleashing the Galick Gun in retaliation.
  • During the Namek Saga, Freeza is presented as an Invincible Villain, barely putting any effort into the fights with Krillin, Gohan, Piccolo, and Vegeta. Even when Krillin cuts off Freeza's tail with his Kienzan, the latter is more mildly inconvenienced than injured, with the tail growing back when he enters his final form. Goku himself can barely hang on during his own bout with Freeza, the latter only fighting him with half of his full power, the former barely keeping up by using the Kaioken technique. Goku tries using the Kaioken to power himself up even further, firing a giant Kamehameha at the galactic tyrant, though Freeza manages to block it with one hand. Unlike previous attacks Freeza had shaken off throughout the Saga, he is actually shocked, wondering how Goku got enough power to even singe his hand. At which point, Freeza stops playing around and takes the fight more seriously.
    Freeza: That...hurt. It hurt!!!
• Asagami Fujino of The Garden of Sinners has no sense of pain thanks to being medicated since she was a small child to seal her psychic powers. She first gets it back in fits after she's hit with a baseball bat by a group of thugs who had just raped her, and proceeds to kill all but one of them because the pain makes her feel both more alive and murderous.
• JoJo's Bizarre Adventure: Stardust Crusaders: During Jotaro and DIO's Pummel Duel early on in their fight, Star Platinum lands a glancing blow on The World's face, causing DIO to glance at the result of the Synchronization.
• In Naruto, when Gaara battles Sasuke in the Chunin exams, Sasuke manages to get through a barrier of Gaara's sands with his Chidori and draw blood. This makes Gaara freak out and he cancels his attempt to transform behind the barrier.
• One Piece:
  • Dellinger of Donquixote Pirates was rather smug and feeling untouchable, right before being cut by Hakuba (alternate personality of Cavendish which awakes when he's unconscious) without realising how it happens. He stopped dead in his tracks. Then it turns into a big Oh, Crap! moment then into a Villainous Breakdown before Dellinger was defeated by repeating cutting seconds later.
  • Pearl of the Krieg Pirates claims he's never lost a drop of blood in battle. When Luffy accidentally gives him a nosebleed, he unleashes his Fire Pearl technique.
• Overlord (2012): When the Sunlight Scripture summon a Dominion Authority to fight Ainz, it unleashes a holy attack that deals noticeable damage to him. He stands in the pillar of light and remarks on how he's feeling for himself the damage his in-game character always experienced, before dismissing it as a threat and obliterating it with Black Hole moments later. Albedo takes it a lot worse than him.
• In the Stars arc of Sailor Moon after fighting a hopeless battle against Galaxia, the Sailor Starlights all pool their energy together to launch a brutal Combination Attack that not only breaks Galaxia's until-then iron defense but gives her a bloody wound. Unfortunately for them, making Galaxia actually bleed pisses her off so badly that she revokes any semblance of mercy she had been showing and swiftly pulverizes the three of them with the full intent of completely destroying them in body and spirit.

Asian Animation

• Pororo the Little Penguin: In "Rody's Wish", Rody has a dream in which he's an organic being rather than a robot. When he and Eddy accidentally bump into each other, Rody takes a moment to realize that he feels pain for the first time and that this means he's no longer a robot.

Comic Books

• In Supreme Power, a Marvel take on the DC Universe, Hyperion (the local Superman Substitute) feels pain for the first time while fighting Doc Spectrum (their version of Green Lantern). Hyperion, whose senses and biology render him immune or unable to be stimulated by almost anything on Earth, appears thrilled by this and immediately demands that Spectrum do it again. Spectrum is understandably weirded out by this and promptly runs away from the fight.

Fan Works

• The Boys: Real Justice:
  • The beast brought to New York by Felix Faust manages to injure Homelander, who's never been injured in his life. He then sees Superman and the Justice League take out the monster with no serious effort. The injury plus his own unstable mental state lead to him having a barely-concealed vendetta against the Justice League, especially Superman.
  • A downplayed example with the Boys in Gotham. They all get beaten and have their lives threatened a few times by Gotham's rogues before the Boys are captured by Batman (more for their own safety than anything) and sent to Arkham. This is the first time the Boys feel like they're in over their heads, as they aren't Anti Heroes here, just a bunch of thugs who don't know what they're doing.
• Hysterical: Aizawa erasing Izuku's Quirk causes him to become capable of feeling pain for the first time in a decade. As Izuku currently has four broken limbs, he immediately collapses in agony, screaming at the top of his lungs. Once Aizawa reflexively turns off his Quirk, Izuku describes the sensation as a major rush before deciding he doesn't like it.
• In a trollpasta called It's Your First Kiss, Charlie Brown (based on the Peanuts special of the same name), this is inverted. Charlie Brown's head bleeds due to being hit with a rock, and Linus is the one to react in horror, screaming, "What is that?!" The narrator is rather bemused about the fact that these kids don't know what blood is by now.
• Never Say Never: Mukuro Ikusaba was well-known as the Ultimate Soldier because she never received an injury from battle, but this also gives her very low pain tolerance. So when Makoto saves her life and only Mukuro's hand gets impaled, Mukuro reacts to the injury screaming in agony.
• In The Weaver Option, Necrons lost all sense of pain millions of years ago as a result of their bio-transference. When Taylor strikes Phaeron Djosakhat with an Anathema-powered blow, the resulting psychic wound causes him to feel pain again. This proves debilitating as the Phaeron cannot focus on anything except the pain he is feeling until it is far too late to save the battle.

Films — Animation

• Bolt: Bolt's paw bleeds a bit after he and Mittens jump out of a moving truck. Since he's been living in a recording studio all his life and has never been in any real danger, he's confused by this leakage of "red liquid". Mittens is incredulous that he doesn't know what blood is by now, but Bolt mistakenly believes that Styrofoam was what weakened him in the first place.
• Ed, Edd n Eddy's Big Picture Show: Eddy's older brother is quickly knocked out after being hit in the face with a steel door. Word of God has said that this is because he's been torturing people all his life, but never felt any real physical pain himself, so he hadn't gained much of a resistance to it then.
• Jinxy Jenkins & Lucky Lou: Lucky Lou always has good luck, which keeps her from harm but makes her life boring. When she bumps into Jinxy Jenkins, who has bad luck, she falls down and gets a scrape on her palm. She examines it and gets an expression of wonder.
• Puss in Boots: The Last Wish: In his Bravado Song at the start of the film, Puss boasts that he's never been touched by an opponent's blade. This changes soon after when he meets the Wolf, who manages to outclass him in combat and get a nick on his forehead, complete with blood. This experience, combined with the knowledge that he is down to the last of his nine lives, traumatizes Puss and sends him scurrying for his life and leaves him terrified of the Wolf, to the point that one encounter sends him into a full-blown panic attack.

Films — Live-Action

• In the climax of 300, Leonidas hurls a spear at Xerxes, giving him a slash on his cheek this way. Xerxes' reaction is one of shocked incredulity, as very apparently, he bought into his God-King shtick so deeply he didn't even see getting hurt as possible at all, let alone likely.
• Avengers: Infinity War: Downplayed. Big Bad Thanos has been hurt and defeated before in his past, but during the climactic battle where all the heroes attempt to fight him, he is left uninjured during the entire bout until Iron Man lands a powerful slam on his face, cutting him. Thanos pauses to feel his minor wound, remarking "All that for a drop of blood."
• The Cell: As one of Stargher's demonic personalities tortures and mocks Peter, Catherine breaks free from Stargher's control, sneaks up behind, and stabs him in the arm with one of his surgical implements. Stargher pauses, looks at his wound with disbelief (since nothing in his dreamworld has ever fought back before), then lets loose a hellish high-pitched scream of pain and surprise.
• After the climax of Constantine, Humanity Ensues for the angel Gabriel as divine punishment for trying to orchestrate the apocalypse. Constantine, on learning this, promptly punches them in the jaw, leaving them doubled over in anguish. John quips: "That's called pain. Get used to it."
• Legolas has this reaction in The Hobbit: The Desolation of Smaug when he meets his Worthy Opponent in the form of Bolg, who manages to actually give Legolas a nosebleed. Legolas is clearly confused by the experience, and briefly looks at his own blood with surprise before going after Bolg again.
• King Kong (2005): During the Empire State Building showdown, Kong is clearly shocked to find out airplane bullets left a gaping hole in his chest, a clear sign he won't get out of there alive.
• Kamawas, the main villain of The Malay Chronicles: Bloodlines, is invulnerable to all damage thanks to his magic voodoo amulet, which he has been wearing for several decades while committing raids and widespread massacres, to the point he forgot what pain feels like. Prior to the final confrontation, his amulet is pickpocketed by Princess Li-Hua (when Kamawas pulls an Attempted Rape on her), which slowly deprives him of his invincibility, leading to Kamawas actually bleeding when Prince Marcus manages to land a lucky hit on him. And for the first time in ages, fear forms on the villain's face.
• Superman II: When a Brought Down to Normal Clark Kent gets sucker-punched, he's outright addled by the injury, and doesn't fare any better in the ensuing Diner Brawl.
  Clark: Blood. It's my blood. I think... maybe we ought to hire a bodyguard from now on.

Literature

• Dinotopia: Bix the Protoceratops is the first dinosaur whom Arthur and Will Denison meet after washing ashore. In a panic at the sight of a live dinosaur, Arthur throws a rock and hits Bix in the leg. Bix starts howling in pain despite the minor injury, because as a diplomat on an island where violence is vanishingly rare, being physically attacked is something that basically never happens to her.
• In The Hope of the Redoran, one of The Elder Scrolls In-Universe Books, Andas is impervious to disease, poison, and magic, and "his blood shall never drop on the ground." When he is injured for the first time in his life by an opponent armed with a simple club, he's so stunned that he drops his sword.
• In the climax of the He-Man and the Masters of the Universe book "He-Man Meets The Beast", the titular Beast is briefly stunned when Orko, hoping to buy Prince Adam time to transform into He-Man, flies up and punches it on the nose as hard as he can. The blow itself wasn't particularly strong, but it was hard enough for the Beast to realise that Orko had actually attacked it, and was so surprised that Orko wasn't intimidated by its size and terrifying appearance that it actually stops in its tracks while it tries to process this. Then Adam completes his transformation into He-Man, and the Beast flees in terror as it realises He-Man is a lot more powerful than it is.
• In "The Immortal" by Jorge Luis Borges, Rufus accidentally scratches his hand on a thorny tree, his first injury in almost two thousand years. He's overjoyed by the evidence he's finally found an end to his immortality.
  The unaccustomed pain seemed exceedingly sharp. Incredulous, speechless, and in joy, I contemplated the precious formation of a slow drop of blood. I am once more mortal, I told myself over and over, again I am like all other men.
• In The Orville novella "Sympathy for the Devil", Mercer convinces Adam that he's been living in a simulation for his entire life by punching him in the face, the sim's safety protocols having prevented him from feeling pain up to that point.
• The Reckoners Trilogy: In the prologue of Steelheart, the titular Epic is grazed by a bullet shot by David's father, after a hail of bullets failed to affect him moments earlier. He wipes the wound and is visibly astounded to see blood on his hand. It's enough for Steelheart to deem David's father important enough to kill with his own gun, and he sets to destroy the bank they're in within the span of a few seconds to ensure that no witnesses to his weakness will be left alive.
• Red Dwarf: In Last Human, Kryten uses a DNA modifier to transform him from a mechanoid to a human. Soon after, an accident caused by the Cat's clumsiness causes Kryten to fall down a flight of stairs, sustaining many injuries one after the other (in what the narration calls his "introduction to pain"). Kryten is not just in agony but outraged that his pristine new body is already a "write-off" due to a nasty scar on his leg.
• In the first Ringworld book, Teela has never experienced serious injury or pain thanks to her inborn natural luck. When their spaceship crashes, she blithely attempts to climb out of the burning hot crater without protection and is shocked when it burns her feet.
• In Orson Scott Card's The Tales of Alvin Maker series, a large violent man named Mike Fink was tattooed shortly after his birth with a hex that made him invincible. After the hex is broken, he is completely incapacitated by the pain from a single blow, as he has never felt pain before.

Live-Action TV

• Barry: Downplayed, as Barry isn't unfamiliar with injury (getting beaten up hand to hand and stabbed with a kitchen knife among other things). But despite pouring boxes of bullets into various enemies over the series, Barry doesn't get shot himself until he takes one to the shoulder in the last episode; he flops into a chair, looks bemusedly at his own blood, and simply says "Oh, wow." Also his last words, as Gene delivers the coup de grace.
• Doctor Who: In "Evolution of the Daleks", Dalek Sec becomes a human-Dalek hybrid and gets to experience life outside his travel machine. He specifically notes that he's the first of his kind in millennia to feel physical pain.
• Lois & Clark had the titular characters travel into the bodies of their earlier reincarnations. Clark is surprised when his current body is injured by an arrow.
• Power Rangers RPM: After Dillon reveals to Tenaya 7 that she is his sister, meaning that she is actually human-bot hybrid rather than a full bot, she lashes out and attacks him. In the ensuing fight, she sustains an injury on her arm that bleeds human blood for the first time she can remember, proving Dillon was telling the truth and causing her to stare at it in shock before running off. Downplayed, since Tenaya has been injured before, but only on parts of her body that were clearly robotic.
• This occurs multiple times in Smallville. Oftentimes, the first indication that a villain is an actual threat to Clark is when they hurt him enough to draw blood. Clark will almost always touch the wound and look at his blood with shock.
• Star Trek: The Next Generation:
  • In "The Child", a noncorporeal alien takes the form of a fetus that rapidly grows into a little boy. When he reaches into some boiling hot soup, he's surprised that it hurts since he's never felt pain before.
  • When Q is temporarily Brought Down to Normal in the episode "Déjà Q", he gets stabbed, stubs his toe, and at one point hurts his back and calls it "incredible".
• Star Trek: Voyager: In "Revulsion", Seven of Nine gets her first injury (an abrasion on her hand) after having no longer been Borg. Being "damaged" concerns her.
• Supergirl (2015): Occurs multiple times when nigh-invulnerable Kara gets depowered or realizes she's met her match. "Red Faced" ends on the cliffhanger of Kara cutting herself on glass and bleeding, something that hasn't happened since she came to earth. She stares at her finger, uttering a quiet, shocked, "I'm bleeding". In the next episode, "Human for a Day", she discovers she temporarily burned out her powers from excessive use of heat vision.

Music

• The song "Tonight is the Night I Fell Asleep at the Wheel" by Barenaked Ladies is from the perspective of someone who Fell Asleep Driving and got in a car accident. The narrator takes note of the serious injuries this caused him, such as commenting on the Sickening "Crunch!" he heard as he hit the ground, as well as mentioning that he's never seen so much blood before.

Toys

• BIONICLE: A secondary power of Toa is immunity to their own channeled element. As such, when the Bohrok-Kal depower the Toa, the challenge of fighting back without powers is further complicated by the Toa's increased vulnerability. Kopaka the Toa of Ice now feels cold in a blizzard, Tahu Toa of Fire now can't just tank a plasma attack from an opponent, etc.

Video Games

• Final Fantasy VI: When Kefka gives Celes a sword as one last offer to betray the heroes and return to the Empire, Celes instead turns the sword on him. He immaturely cries about his wounds before he takes the Warring Triad's powers for himself to destroy the world.
• God of War:
  • In God of War (PS4), when Baldur is stabbed by the mistletoe arrowhead and feels the pain, he stops fighting to laugh in glee at the return of his senses. Also overlaps with Not His Blood, when Kratos sees blood on Atreus after the exchange, who clarifies whose blood it is.
  • In God of War Ragnarök, Heimdall is gifted with Combat Clairvoyance and is fast enough to casually dodge most attacks he can see, making him quite smug about it. When someone does manage to hurt him, it gets a reaction out of him:
    • At the end of a Curb-Stomp Battle Heimdall serves out to Atreus the first time he visits Asgard (in which Atreus can't hit him once), Atreus decides to fire an arrow at his head from behind. Heimdall manages to catch the arrow, but he doesn't do it quite right, which means the arrow gives his hand a small nick and sprays a little blood onto his face. Judging by Heimdall's expression, he clearly wants to hurt the boy even more, and the only reason he doesn't is that Thor shows up and intimidates him into standing down.
    • Heimdall has a decidedly less positive reaction to Kratos being the first to land a direct hit on him in a long time. While he starts the fight taunting and provoking Kratos, confident that the Ghost of Sparta will die before he can even scratch him, he briefly loses it when Kratos eventually punches him hard enough to draw blood.
      Heimdall: You... actually HIT ME!
• While no blood is shown onscreen, one of Odie O'Bright's potential voice lines when defeated in the remake of Live A Live is "Is this... my... blood?"
• Mega Man 8-Bit Deathmatch: Sunstar in V6's story spends his first phase throwing out "low-effort" attacks such as meandering toward Maestro to throw him into a wall, and doesn't even have a health bar. But once you hit him enough, he takes a scratch, pauses to observe it, and promptly goes from 0 to 100, where the real fight begins.
• Downplayed in Metal Gear Rising: Revengeance. After being fatally stabbed by Raiden, one of Jetstream Sam's last motions before he collapses is to stare at his own blood-soaked hand. Though this is not his first severe injury ever, it is the first he's sustained since gaining his robotic arm. The shot is more meant for the player's reaction, as they discover he was still mostly human.
• Phoenix Wright: Ace Attorney: Part of the backstory is that von Karma took his first, and only, vacation to recuperate after being given his first penalty. And a stray gunshot to his shoulder.
• In Act 2 of ULTRAKILL, Gabriel revels in his own blood being drawn for the first time, accepting V1's strength as a match for his own. This incites him to rebel against and massacre the Council.

Web Animation

• DEATH BATTLE!:
  • In the episode "Beerus vs. Sailor Galaxia", both combatants start out dismissing each other as a threat, even stooping so low as to engage in a Finger Poke of Doom Pummel Duel, until they poke each other's fingertips so hard it hurts both their arms. Much like in the example from her series of origin, Galaxia shouts "Ridiculous!" and tries to instantly destroy Beerus, with him responding in kind with his Hakai.
  • In the episode "Omni-Man VS Homelander", Omni-Man breaks Homelander's nose and the latter covers his face, reacting in shock as he sees blood in his hands afterwards. And then Omni-man punches him again.

Webcomics

• One super from Grrl Power claims, "My skin is impenetrable and my claws can cut through anything." When Sydney demonstrates that his claws are capable of cutting through his skin, he faints after seeing his own blood for the first time.
• In Kid Radd, after Sheena (an invulnerable NPC character) is combined with her Promoted to Playable sequel iteration (and thus gains a lifebar and damage animation) and is hurt for the first time, she screams her head off about it. This prompts her boyfriend to comment "What, did you never get hurt before-oh right..." Luckily, she learns she can swap between her Magical Girl Warrior player-character version and invincible NPC version at will.
• R.A.M. the Robot: After being temporarily transformed into an organic being, R.A.M. gets scratched up by her pet-alien-that-looks-like-a-cat and feels pain for the first time. She finds it hilarious.
• S.S.D.D.: Lee is a clone soldier who was designed not to feel pain, but fell into enemy hands who took him in as their own. After receiving Super-Soldier implants that fixed that feature, he spent the day inflicting pain on himself and testing his new Healing Factor.
• Strong Female Protagonist: Alison, formerly the Flying Brick superhero known as Mega-Girl, battles the villain Cleaver whose hands are blades sharper than any material in the world. She defeats him but gets a slash to her head, and becomes woozy as her near-impenetrable skin means she's never felt pain before. Her first reaction to seeing her own blood on herself is thinking someone else put it there.

Web Original

• Dice Funk: In Season 5 we meet Vinnie Caravella, a gangster whose Conduit is Invincibility. During the final battle he confronts his adoptive brother Dregg, unfortunately for Vinnie the Tuff Bastards have found a way to remove people's Conduits and after taking his away Dregg lands one huge punch on Vinnie which leaves him uncontrollably sobbing on the floor from the first pain he's ever felt in his life.
• Dr. Horrible's Sing-Along Blog: After Dr. Horrible's gun explodes in his face, Captain Hammer's reaction suggests he's never been injured before.
  Captain Hammer: Ohh, I'm in pain! I THINK THIS IS WHAT PAIN FEELS LIKE! Oh, Mama! Someone maternal! GET OUT OF MY WAY! [Runs away]

Western Animation

• Big Guy and Rusty the Boy Robot: In "World of Pain," Rusty is upgraded with alien technology that allows him to actually feel human senses instead of just detecting things. The next time he enters battle and takes damage, he starts to say, "No pain receptor—" then cries out in agony. He becomes terrified of getting hurt until he finds a way to rid himself of the alien tech.
• Doc McStuffins: In "Oooey Gablooey Springs a Leak", Oooey Gablooey gets a cut on him. He's a Living Toy, so he leaks blue goo instead of blood, but he's still frightened and confused as to why he's leaking.
• Family Guy: In the episode "One If By Clam, Two If By Sea", Peter and his friends get what amounts to a Last-Minute Reprieve from their Frame-Up minutes before Steve Bellows (the Serial Killer put away years ago by the force Joe was on) gets to make good on his threat to kill them in retribution. Left to his own devices, he cuts his arm to see how it feels. Realizing the pain, he happens on the revelation that he really does deserve to be locked up.
• Futurama: In "Insane in the Mainframe", Fry is mentally broken into thinking that he's a robot. At the end, this allows him to fend up Robotic Psychopath Roberto, but the robot manages to cut his arm. As a result, it is seeing the blood coming out of it which convinces Fry that he's human all along since robots aren't able to bleed that way.
• My Life as a Teenage Robot: When XJ9, annoyed at her inability to physically feel, reinstalls some old nerve receptors, their pain setting makes her unable to fight Himcules, a Villain of the Week who literally draws strength from hurting people. The problem gets solved when the setting gets changed from "pain" to "tickle," and Jenny laughs at him until his strength drains.
• Pibby: After sustaining a serious, unspecified eye injury offscreen, Pibby is seen hunched over, voicing her confusion about the "red water" pouring out of her, having never seen blood before.
  "What's that red water? I've never seen that before..."
• Rugrats: In "The First Cut", Tommy Pickles cuts his finger. Seeing as he's just a baby and it's the first time he's ever bled, this confuses and frightens him.
• The Simpsons: In the episode "Bart the General," Bart manages to land a hit on Nelson during their first encounter in the episode. Nelson's nose bleeds; at first, he thinks that it's Bart's, but he soon realizes that it's his own blood and gets angry.
  Weasel: Nelson, you're bleeding!
  Nelson: Nah, happens all the time. Somebody else's blood splatters on me. (sniffs) Hey, wait a minute. You're right! (to Bart, scowling) You made me bleed my own blood!
• South Park: In "Grounded Vindaloop", Cartman tricks Butters into thinking he's in a VR simulation, leading him to go on a reckless rampage through town, thinking there won't be any consequences. When Butters gets stabbed by a prostitute, he comments on how real the pain feels before realizing that the blood coming out of him is not virtual.
• Teen Titans Go!: In "Real Boy Adventures", Cyborg loses his robotic parts and becomes fully human. At one point, he gets a papercut on his finger (which confuses him until Starfire clarifies that it often happens to those without metallic hands) and then stubs his toe. He's quite distraught and annoyed that human skin is so sensitive.

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