The first Anthology starts off with something called My Little Jackass. The hilarious part is that they had to edit almost nothing to get the exact flavor of idiotic shenanigans from the show. Also, "sexy saxophone Spike" and Fluttershy's song to animals.
The Long List for making Doritos.list Staff of Anubis, Seth's stupid hat, The TARDIS, Starswirl the Bearded's beard, Zecora's rhymes, pre-existing Doritos, glue, more glue, even more glue, lucky Angel's foot, Kybdis vectors, fandom insanity, manticore claw, Mike's dignity, tears, dragon's fire breath, cake frosting, Heart's Desire, pegasus feathers, Applejack's cutie mark, salt, quills and sofas, chapstick, cherries, kumquats, griffin beak, Twizzle's beard, Bon Bon's voice actors, bananas, poison joke, oxen, Ursa toenail, big crown thingy, BVid's Q and A video, Burnt Twist x 1000, earth, fire, wind, water, heart, Go Planet, Fire Ruby, industrial lard, love, uranium, tuft of cloud, color of rainbow
During the "Equestria Girls" sequence, one scene has Sunset Shimmer being arrested for the chaos she caused at Canterlot High. We are then treated to a brief shot of a newspaper article about the event, with the rest of the page being taken up by an article about moose-farming.
One clip is styled as an installment of Hinterland Who's Who, a series of short Canadian nature documentary films that aired on TV in the 1960s and 1970s.
Spike and Discord as Rick and Morty, pointing out various Off-Model animation goofs seen in the show itself.
Rarity is dragged beneath the earth... and ends up in the Ruins. Flowey's appearance (read: with M.A. Larson's face photoshopped on) is only icing on the cake.
Even a bit that got hit by copyright managed to be funny. A sketch that involved the Kirin got the audio muted on it because of copyright. The audio in question, that you can hear a brief second of before it's muted? Depeche Mode's "Enjoy the Silence". Talk about Irony.