A student at Leafmore High, Shannon Matthews stays after school after her brother Kenny goes missing, as it is the first place to look for clues and she suspects (correctly) that that is where he went missing. Canonically, she survives the experience.
In the second game, Shannon has become a student at Fallcreek University, and has taken on a much darker personality. Of the first game's survivors, she is the only one who's been able to adapt to the mortifilia infection, which has driven a wedge between her and Kenny, who needs pills to suppress the infection. She survives the game, helping her boyfriend Stan kill her brother Kenny at the end.
- Action Girl: In ObsCure II.
- Broken Bird: In the second game.
- The Chick: In the first game. By the second, she's taken several levels of badass.
- Final Girl: In the first game, her personality and appearance are heavily inspired by the "final girl classic" model of Laurie Strode or Sidney Prescott, being the more modest and less abrasive of the two female characters. (Not so much in the second game, though.) She's the only female character to survive the events of both games.
- Girl Next Door: In the first game.
- Goth: Becomes one after the traumatic events of the first game.
- Hotter and Sexier: In the second game. To a lesser extent, this is also true of her New Game+ outfit in the first game, which is a much biggest change from her normal outfit than the other four characters get.
- Kill the Ones You Love: Kills her brother, Kenny, at the end of the second game.
- The Medic: One of her skills in the first game is using first aid kits more effectively.
- The Smart Girl: She was an ace student in high school, and her skills in the first game were offering puzzle tips and knowing first aid.
- Team Mom
- Took a Level in Badass: Is the only one to successfully adapt to the Mortifilia, and is actually capable of inhaling the spores without harm.
- Took a Level in Jerkass: Shannon in the first game: a kind, sweet, caring Girl Next Door. Shannon in the sequel: a goth chick who berates her brother's "weakness" in being unable to suppress his infection.
A student at Leafmore High, Stan Jones is a layabout slacker who is failing his classes. While he puts on a Pretty Fly for a White Guy
attitude, he's otherwise fairly mellow, and is friends with Kenny. He gets dragged into the events of the game when the main gang stumble upon him hacking into his school records and offering to do the same for them. Canonically, he survives the experience.
After the first game, Stan dropped out of school and spent some time in jail, and by the second game he's a pizza delivery boy. He needs to take medication to suppress the mortifilia infection. He survives the game, helping his girlfriend Shannon kill Kenny at the end.
A student at Leafmore High, Kenny Matthews is a player on the school's basketball team. One day after practice, he is kidnapped by Principal Herbert Friedman to use as a test subject for experiments with the mortifilia plant, later to be rescued by his sister Shannon, his girlfriend Ashley, and his friends Stan and Josh. Canonically, he survives the experience.
In the second game, Kenny has become a student at Fallcreek University. He needs medication to suppress the mortifilia infection, which drives a wedge between him and his sister Shannon, who has learned to suppress the infection without medication and frequently urges him to do the same. After running out of medicine, Kenny mutates into a giant monster, and proceeds to kill Mei and Corey, as well as kidnap, rape, and impregnate Amy. He is put down by Shannon and Stan in the finale.
A student at Leafmore High, Josh Carter is a school newspaper reporter who offers to help Shannon and Ashley search the school for evidence of Kenny's location after hours. Canonically, he survives the experience. Afterwards, he and Ashley returned to the ruins of Leafmore High, where they were attacked and presumably killed by Jedidiah.
A student at Leafmore High, Ashley Thompson is a cheerleader who is dating Kenny Matthews. After Kenny goes missing, Ashley is initially annoyed, but begins to worry for his safety after Shannon tells her that she hasn't seen him either, and so she helps to search for him at school after hours. Canonically, she survives the experience. Afterwards, she and Josh returned to the ruins of Leafmore High, where they were attacked and presumably killed by Jedediah.
A student at Leafmore High, Dan was kidnapped by Principal Friedman before the events of the game. He offers to help Kenny escape from Friedman's clutches, but is killed in the process.
The principal of Leafmore High, Herbert Friedman is also kidnapping and carrying out grotesque experiments on his students. He and his brother Leonard went on an expedition to Africa to discover the secret to immortality, and discovered the mortifilia plant, which seemed to have such properties. While the plant worked on Herbert and his wife, Elisabeth Lucy Wickson, it had disastrous effects on Leonard, turning him into a monster. Distraught, Herbert founded Leafmore High as a cover for his experiments and to have a steady stream of test subjects, hoping to find a way to save Leonard. At the end of the game, he is killed by Mr. Walden, who had gone crazy due to his mortifilia infection.
- Big Bad
- Dean Bitterman
- Mad Scientist: He's been kidnapping and experimenting on students in his lab beneath the school.
- Obviously Evil: No bones are made about the fact that he's up to his nose in what's going on at the school, even if the game takes some time to spell out exactly what that is.
- Really 700 Years Old: He's well over a hundred years old, but due to his experiments, he hasn't aged since the early 1900s.
Herbert Friedman's brother. He and Herbert discovered the mortifilia plant while on an expedition to Africa to find the secret to immortality, and while it worked on Herbert and his wife, it turned Leonard into a monster. He now lives in the school's basement, having grown into a giant Plant Person
whose roots stretch across the campus. He is killed at the end of the game by the protagonists, serving as the Final Boss
. The second game reveals that he was Not Quite Dead, using his son Jedidiah to take care of him and spread the mortifilia plant around Fallcreek University. Both of them are killed at the end.
- Big Bad: Of ObsCure II, having survived the final battle at Leafmore and uses his son Jedidiah to spread the Mortifilia into the Fallcreek campus.
- Final Boss: Of the first game.
- Not Quite Dead: Survives the final battle and goes on to become one of the Big Bads of the second game.
- Plant Person
A biology teacher at Leafmore High, Denny Walden learned about Friedman's experiments, and attempted to investigate for himself. He escaped, but got himself infected and
accidentally released the mutated test subjects onto the campus. He tries to help the main characters, but slowly goes insane from the infection, eventually killing Friedman in an attempt to get the cure. He is then killed by Leonard.
- Badass Teacher
- Sacrificial Lion: He gets killed by Leonard just after shooting Herbert Friedman.
- The Smart Guy: In between teaching biology classes, he also figures out how the Mortifilia plant works.
- Zombie Infectee: He was infected early on, causing him to behave more erratically as the game progresses. By the end, he is too far gone to safely use the antidote — not like it would've saved him from getting killed by Leonard anyway.
The nurse at Leafmore High, Elisabeth Lucy Wickson is also Herbert Friedman's wife. Like Herbert, she was granted immortality by the mortifilia plant. She is killed by monsters offscreen.
A student at Fallcreek University, Corey Wilde is a daredevil skater whose first and second love are his girlfriend Mei Wang and his muscle car. Corey and Mei try to sneak into a Delta Theta Gamma party just as it was being overrun by mortifilia monsters, and they must fight their way out and try to survive and stop the outbreak. At the end of the game, with his car trashed, Mei dead, and infection coursing through him, Corey is Driven to Suicide by Kenny.
A student at Fallcreek University, Mei Wang is a computer whiz and gamer who is dating Corey Wilde and whose roommate is her beloved sister Jun. While Mei and Corey are sneaking into a Delta Theta Gamma party, it is overrun by mortifilia monsters, and they must fight their way out and try to survive and stop the outbreak. She is killed by Kenny, who crushes her head beneath his foot in front of Corey.
A student at Fallcreek University, Sven Hansen is a Norwegian exchange student who plays on the school hockey team and dates Amy Brookes. He and Amy were at the Delta Theta Gamma party when people started mutating, and had to fight their way out. He is killed by Jedidiah and hanged on a meat hook.
A student at Fallcreek University, Amy Brookes is a bubbly, yet intelligent, girl who is dating Sven Hansen. The two of them were at the Delta Theta Gamma party when people started mutating, and had to fight their way out. She is kidnapped, raped, and impregnated by Kenny, and is later captured by Delta Theta Gamma, who seek to study her mutant offspring. She gives birth to a monster, which destroys the helicopter she was in and presumably kills everyone on board.
A student at Fallcreek University, Jun Wang is Mei's sister and roommate. She helps get Sven and Amy into the Delta Theta Gamma party, and is later trapped in her dorm when monsters attack. Despite Corey and Mei's best efforts, the monsters succeed in getting to Jun.
Professor Richard James
A professor of biology at Fallcreek University, Richard James assists the students in their quest to end the outbreak, supplying them with upgrades to their batteries and healing items. He also works for Delta Theta Gamma, and helps them kidnap the survivors after Leonard and Jedidiah are defeated. He is presumably killed when Amy gives birth, her mutant offspring destroying the helicopter they were in.
Jedidiah is a mad, mentally damaged man who lives in an empty, decaying mansion in the woods, occasionally venturing out to kidnap and murder people. He is Leonard Friedman's son, and serves to care for his father and spread the mortifilia plant around the Fallcreek campus. The two of them are killed at the end of the game.