These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Fake Difficulty: Square tried to make II more like the Resident Evil games, but with worse camera angles and an absolute lack of a quick, 180-degree turn. Many cheap shots and deaths will ensue. The original game generally favored more isometric viewpoints that, shock of shocks, showed most of a room without any awkward and abrupt angle transitions.
Narm: A lot of the ANMCs have really goofy looking faces for such hideous monsters, possibly because they look somewhat human from the transformation.
The fat ANMCs and the aquatic ones make a silly "Ohh" noise when they are attacked or attack, respectively.
Many people also seem to agree that the horse-like sound the creature the young woman at the Akropolis café transforms into effectively ruins the scariness of the scene.
Paranoia Fuel: The Stalkers are chameleon-like monsters with an Invisibility Cloak. Unlike other monsters in the game, they can't be seen if they are in a room. You will only know if they are there if you suddenly enter the battle screen to a very loud, unnatural screeching noise.
Knight and Bishop Golems are even worse. You don't detect them until they attack you, and they always land the first hit.
Uncanny Valley: Most of the ANMCs in the game are animals with vaguely human-like characteristics. 'Strangers' are Ostrich/Dinosaur-like things that can mimic corpses and 'Chasers' are basically camels with horrifying, polygonal human faces. Their subspecies 'Mad Chasers' fall on their backs and start laughing when Aya attacks them.