Western Animation / The Powerpuff Girls
aka: Powerpuff Girls

From left to right: Bubbles, Blossom, and Buttercup.

"Sugar... spice... and everything nice. These were the ingredients chosen to create the perfect little girls. But Professor Utonium accidentally added an extra ingredient to the concoction: Chemical X! Thus, the Powerpuff Girls were born! Using their ultra-superpowers, Blossom, Bubbles, and Buttercup have dedicated their lives to fighting crime and the forces of evil!"

Note: This is the page for the original series. If you're looking for the 2016 revival, Go here.

One of Cartoon Network's most popular original series, originally called "The Whoopass Girls" by creator Craig McCracken (they were created with "sugar, spice, everything nice," and a can of Whoopass) before it got picked up by the network during The Renaissance Age of Animation. The Powerpuff Girls revolves around a Power Trio of Little Miss Badasses who fight crime in the fictional city of Townsville. These Artificial Human girls, who have no fingers, toes, flat feet, ears, or noses, were created when Professor Utonium accidentally added Chemical X to his mixture of sugar, spice, and everything nice.

The series' heroes are Blossom, "commander and the leader," who often acts the Drill Sergeant Nasty; Bubbles, "the joy and the laughter," whose personality is very similar to that of her namesake from Jabberjaw (but not quite a Dumb Blonde), and Buttercup, "the toughest fighter," and a tomboy with a bad attitude. Their simian Arch-Enemy Mojo Jojo wears a helmet to cover his enlarged brain and speaks in a manner reminiscent of bad anime dubbing. Aside from the obvious Anime influences, most of the series' supporting characters are drawn in the style of 2 Stupid Dogs (not surprisingly, as the creator of the show worked on that cartoon).

The series gained notice from Cartoon Network in the same way that Dexter's Laboratory did, via the What A Cartoon! Show contest for nonprofessional animators. It's possible that the two series have a Shared Universe; the animation is very similar, the creators for both series collaborated on both series, and "TV Puppet Pals" and superheroes like Major Glory and Val Hallen appear in both series.note  In addition, both cartoons (as well as Johnny Bravo) were introduced via the Space Ghost Coast to Coast special, World Premier Toon-In, and the Powerpuff Girls pilot aired after the special.

Warner Bros. released an animated feature, The Powerpuff Girls Movie, in 2002 (which bombed at the theaters, likely due to a severe decline in popularity that began in early 2001). A comic book series (from DC Comics no less). An anime version, Demashita! Powerpuff Girls Z, hit the airwaves in Japan on July 1st, 2006.

Eight years after the show ended (and five after Powerpuff Girls Rule special). The series came back in the form of a CGI special in January of 2014. Most likely as a test pilot for a reboot (though oddly this was after Craig had left Cartoon Network to work with Disney on Wander over Yonder, and even before then he had left the show after season 4). Supporting this is the that the girls returned to comic book format in September 2013, this time under the IDW brand as part of a deal to allow classic Cartoon Network cartoons to be told in new adventures. Sure enough, a reboot of the series was announced for a 2016 release. It eventually premiered in April 2016, for tropes on that show, check its trope page.

The original series was the final production to be created under Hanna-Barbera's name. The studio's assets were absorbed into Cartoon Network Studios following Bill Hanna's death at the end of season 4.

Now has a character sheet.

There is also a recap page that would appreciate some assistance.

Now with its own comics page.

The Girls have appeared in two IDW Crisis Crossover comic book events: Cartoon Network Super Secret Crisis War (with Mojo Jojo; 6 issues, June-November 2014), and Super Smash-Up (5 issues, January-May 2015).

So, once again, your life is ruined, thanks to TV Tropes!