Shout Out: The Powerpuff Girls

  • In "Super Zeroes", The Mayor has a Jigglepuff Watch.
  • "Three Girls and a Monster" features the girls trying, and failing, to stop a giant dinosaur-like monster who is impervious to all of their physical and strategic attacks. In the end, Bubbles simply asks nicely for him not to destroy the city, and he promptly leaves. The monster itself is a nod to Geof Darrow's "Yellow Taoking" from The Big Guy and Rusty the Boy Robot.
  • "Meet the Beat-Alls" is one long string of Beatles references.
  • Speaking of The Beatles, the episode entitled "Get Back Jojo".
  • Additionally, Him has a very similar voice to the Chief Blue Meanie from Yellow Submarine, and according to McCracken, he was a major inspiration on the character.
  • "The Powerpuff Girls Rule" makes as many pop culture references as it possibly can in its 30-minute timeslot. Everything from George Orwellnote  to Mario Kartnote  gets its fair share of homage.
  • "Child Fearing" had the Mayor playing a video game with a character and a HUD that looked suspiciously like those from 3D Zelda titles. The Mayor even killed Navi, accomplishing something OoT fans could only dream of.
  • In "Members Only", you can see Harvey Birdman, Space Ghost, and expys of Captain America and many other comic book superheroes.
  • The girls' big eyes were inspired by the art of Margaret Keane; Ms. Keane is named after her.
  • There's one to 2001: A Space Odyssey in "Coupe D'etat".
    Blossom: This isn't very funny. Open the door, KARR!
    KARR: (close-up on just one of KARR's headlights) I'm sorry, Blossom. I'm afraid I can't do that.
    • This is also a reference to Knight Rider, which featured a villainous prototype of supercar KITT named KARR.
    • Said KARR also transforms into a sentient robot.
    • The idea of an evil car with an unhealthy obsession with its owner also seems to be a reference to the Stephen King story "Christine".
  • "Nuthin' Special"
    • When Buttercup shows off all of her powers in an attempt to find one her sisters don't have, she finally yells out "The Matrix!" and begins to "dodge" backwards in slow-motion.
    • One of the people who can't curl his or her tongue is Gene Simmons.
  • From "Mojo Jonesin'": "Together, you will be a wonderfully diverse and multi-ethnic super hero team, perhaps saving the environment or, whatever."
  • "Dream Scheme" has this reference to The Princess Bride.
    Professor: No buts! I mean it!
    Bubbles: Anybody want a peanut?
  • "See Me, Feel Me, Gnomey"
    • The title is a reference to the recurring "See me, feel me" lyrics (and the eponymous song) from The Who's Tommy. Of course, there must have been more inspiration taken from it as well, with one specific example being a Suspiciously Similar Song to the opening of "Pinball Wizard" playing when the gnome is granting the girls' wish.
    • During the final song, the faces of several villains appear in nine boxes around the screen. "The baddie bunch! The baddie bunch!"
  • "Imaginary Fiend" has Blossom thrown into a pile of coats, emerging dressed as Cartman.
  • In the movie, the spices used to create the Powerpuff Girls are revealed to be parsley, sage, rosemary, and thyme.
  • The title of the episode "A Very Special Blossom" alludes to the NBC sitcom Blossom (starring Mayim Bialik) in which every other episode was a Very Special Episode.
  • In "Knock It Off", there were giant robots in a shot. One had the head of the Mazinger Z. Another had the head of the getter-1, the arms of Grendizer, and the Mazinger's breast fire thing. The last one was blatantly Ultraman. Pretty impressive considering their obscurity outside their home country.
  • There's a certain scene in the movie with Mojo Jojo holding a newspaper headlining the girl's destruction of Townsville. The back page of the paper has a small poster for a certain ape-based virtual band complete with a heading stating that they're headlining Townsville's Music Fest. Cue Troper's head exploding after a second viewing of the film 9 years after watching it in theaters.
  • In the comic book "Trick or Beatings", the following exchange occurs as the Powerpuff Girls (and Mojo Jojo) are out trick or treating:
    Buttercup: I got a gooey bear!
    Blossom: I got a lollipop!
    Bubbles: I got a candy bar!
    Mojo Jojo: Mojo got a rock.
  • In "'Twas the Fight Before Christmas", there's a scene near the beginning where Buttercup worries that waiting until the last minute to send her wish list to Santa might mean she won't get her "official Red Ryder carbine-action 200 shot range model air rifle".
  • In "Jewel of the Aisle", the girls watch a cartoon called Mech-Animals.
  • Then there's Lucky Captain Rabbit King Nuggets, a combination of Lucky Charms, Capn Crunch and Trix.
  • In "Los Dos Mojos", after knocking out Bubbles, who was convinced she was Mojo Jojo, the real Mojo says "One shall be the number of Mojo Jojos in the world, and the number of Mojo Jojos in the world shall be one. Two Mojo Jojos is too many, and three is right out."
  • In the first Rowdy Ruff Boys episode in Season 1, Bubbles crashes through a window and apologizes to the clerk, "sorry about your window, Mr. Looper." with which the clerk states "It's Hooper!! Hooper!!!".
  • In "Collect Her", when the Mayor is trying to determine who the culprit is, one of the names he comes up with is Genndy McCracken. This is an amalgam of two of the show's main writers, Genndy Tartakovsky and Craig McCracken.
  • McCracken received another shout-out in a subsequent episode in the form of a pirate named Crack McCraigan.
  • "Silent Treatment"
  • "Get your paws off me you damn dirty ape!"
  • In "Boogie Frights", when the Boogie Man eclipses the sun with a giant disco ball, the Powerpuff Girls' final assault on the ball is an almost shot-by-shot remake of the Death Star trench run in Star Wars Episode IV.
  • An episode called "Mr. Mojo's Rising".
  • An episode makes a reference to Mega Man, as two police officers ask each other who would win in a fight, Mega Man or Mondo Dude?
  • In "Pee Pee G's", the TV news flash graphic is similar to Kermit the Frog's live on the scene skits on "Sesame Street".
  • In "Octi-Gone", the professor receives a call from Mojo Jojo, who claims that he's holding Octi ransom for 1000 barrels of Chemical X. The professor asks the operator to trace the call... who reveals that the call is coming from inside the house.
  • In "Bubblevicious," Bubbles faces a torture device that goes Up to Eleven.
    • In the same episode, one of the monsters she faces in the danger room bears a striking resemblance to Malebolgia.
  • In "Seed No Evil" a museum tour guide tells the Pokey Oaks class about a caveman frozen in ice. He then says he is going to show them how primitive man used wooly mammoths for dishwashers and pterodactyls for record players.
  • In "Something's a Ms.", the Mayor reenacts The Big Lebowski's epically hammy "Strong men also cry" scene when Ms. Bellum is kidnapped. Later in the episode, the girls use a bag full of the Mayor's underwear as a ringer for the demanded ransom money, as Walter did in the movie.
  • In "The Mane Event", the villain-of-the-week is a giant sphere with one eye, resembling the Eye of Volger from Giant Robo.
  • The episode "I See a Funny Cartoon in Your Future" pays homage to Rocky and Bullwinkle.
  • In "Shut the Pup Up", a TV screen displays a black and white pixilated image of a woman, comparable to an in-game TV commercial in Animal Crossing.
  • "Powerpuff Girls: Dance Pants" features a Rhythm Game within the show called "Dance Pants Revolution"
  • In "All Chalked Up" HIM convinces Bubbles to draw chalk monsters to "express her anger" and brings them to life. One of them is a giant turtle a la Gamera. it doesn't have the tusks though..
  • In "Roughing It Up", the Professor and the girls are at one point panting nature paintings together, and while they do, the Professor sounds and acts like famous TV painter Bob Ross and is even painting a similar mountains-and-trees landscape. To drive the point home further, his head is partly obscured behind a leaf-covered branch making it look like he has an afro.
  • A roundabout one: the show's original title was "The Whoop-Ass Girls," inspired by a friend of Craig's who always used the phrase "open a can of whoop-ass," but he only officially decided to use it when he misheard the lyric "My roof has walls" in The Pixies song "Nimrod's Son" as "My whoop-ass balls."