Actor Allusion: When Femme Fatale challenges the Powerpuff Girls to name some memorable female superheroes, Bubbles mentions Supergirl and Batgirl. Bubbles's voice actor, Tara Strong, voiced Batgirl in The New Batman Adventures some time earlier.
Banned Episode: The Powerpuff Girls series finale "See Me, Feel Me, Gnomey" was banned, allegedly due to being about Communism, but the real reason was the heavy use of strobe effects (which would have triggered epileptic seizures in more sensitive viewers, much like the notorious Pokemon episode "Electric Soldier Porygon"). The episode can now be seen on the complete series DVD set for the show.
Box Office Bomb: The movie, as stated in the main page. Warner Bros marketing for it was quite lousy, but CN did their part and promoted it to heck and back (even [adult swim] got involved). Outside the channel, however, there was barely any mention of it. Not helped at all was that it was pitted against Men In Black 2 on the opening weekend, Like Mike, and the Scooby-Doo live-action movie. Only diehard fans saw the movie, leading to bad box office numbers. It's because of this failure that the series finale movies for Ed, Edd n Eddy and Codename: Kids Next Door were scaled back to made-for-TV fare rather than feature film.
Cristina Hernandez (Blossom) and Rossy Aguirre (Buttercup) voiced Lime and Cherry respectively, two girls from another trio of super-powered girls living with a guy, except their personalities are different between the two series.
Also, Cristina Hernandez, along with Enrique Cervantes (Mojo Jojo) and Sergio Gutierrez Coto (The Narrator) voiced Catwoman, Bane and Batman respectively. That's right, The Narrator is the The Dark Knight and he's fighting against Blossom and Mojo Jojo!
As said on the main page, Craig wanted Jack Black to voice the Gnome in "See Me, Feel Me, Gnomey", but they couldn't due to him being too busy and expensive.
The original tone of the cartoon was meant to be much more adult (it was called "The Whoopass Girls" after all). One can only imagine what that series would've been like if Craig hadn't made it more kid-friendly.
One planned episode, Deja View, about the girls visiting an alternate universe ruled by their evil versions, ended up being cancelled due to the visuals requiring the budget to go overboard (which they were already stretching). It wound up being given to the comic book writers and turned into the 50th issue.