Channel Hop: In the Netherlands, the show was syndicated for the dubbed version, and was moved to Nicktoons for the subbed version.
Cross-Dressing Voices: The main kids in The Offbeats segments were voiced by young children, most notably Mischa Barton as Betty-Anne Bongo. The later episodes had several of the kids' voices sounding a bit lower, including the females (who were voiced by girls). The only adult voice actor was series creator Mo Willems, who voiced September the dog, and Grubby Groo. Not to mention that Henry and June were done by kids, along with Loopy and Larry.
Noah Segan, who did Henry, was also in the 1995 season finale of Married... with Children as a kid blackmailing Kelly into going with him to his elementary school prom, and made occasional appearances on early 1990s episodes of Saturday Night Live as a recurring extra in sketches that called for actual children to appear and not 20 to 30-something-year-olds who can pass as children (albeit overgrown ones).
June's voice actress (Julia McIlvaine) is now on Cartoon Network's Mad voicing various characters.
Some episodes are available on YouTube. Catch them while they're still there.
Production Posse: Rick Gomez plays Sniz, and also was in another show from the creators, The Adventures of Pete & Pete, as bully "Endless" Mike Helstrom. However, Will McRobb and Chris Viscardi (the creators) didn't know that he was going to be on the show (all the shorts had their own casting), and Gomez didn't know that McRobb and Viscardi were working on the show.
Talking To Herself: Dawn and June are both voiced by Julia McIlvaine, if Wikipedia is to be believed.
What Could Have Been: The show was originally going to take place in a live action comic book, with the shorts being Henry and June, Action League Now!, and some old Nicktoons shorts.
Sniz and Fondue's pilot, "Psyched for Snuppa", was one of the two contenders for the fourth Nicktoon in 1992. The show it lost to? Rocko's Modern Life (all things considered, it's not that bad, but still, it would have been nice for Sniz and Fondue to have their own show).
There was going to be a spinoff show called "The Henry and June Show" and focused on Henry and June and premiered in 1999. It had only two segments: the first segment, "A Show of Their Own", featured Henry and June with a studio audience and musical guests. The next segment was "Be True to Your School", where Henry and June attend school, and try their best to tackle hard subjects like "How to Look Your Best". It was never again shown after it premiered. One must wonder what happened to have Nickelodeon cancel it after two segments, and where the clips are now.