The O.C. is mentioned a few other times earlier in season 3, which always prompts the same response from Michael (and once by Bob Loblaw when Michael isn't present).
After Arrested lost it's Monday night prime time slot, they had an episode called Prison Break-in
Fake American: Michael Cera is Canadian, and it often shows from his accent (particularly his pronunciation of "sorry").
Will Arnett is also Canadian but has no discernible accent.
His use of the word "guy", however, is more telling.
Portia de Rossi is Australian, and it rarely if ever shows. (Although once you've noticed her distinctive way of saying "anything", "Mama" and "stupid", you'll never miss it again.)
In the reverse of this, Rita says ironically "You can always tell when they choose an American to play a Brit".
Fake Brit: Rita is a British character played by white South African actress Charlize Theron.
Her uncle Trevor is played by Canadian Dave Thomas.
The Nondescript Ann Veal was played (after her first appearance) by Mae Whitman, AKA Katara.
Mae Whitman plays Roxy Richter in Scott Pilgrim vs. The World, who is about as different from Ann as is possible. Michael Cera (George Michael Bluth) plays Scott.
Jessica Walter (Lucille Bluth) and Judy Grier (Kitty) both voice main characters on Archer.
